- Gastrointestinal motility and disorders
- Digestive system and related health
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Helicobacter pylori-related gastroenterology studies
- Microscopic Colitis
- Eosinophilic Esophagitis
- Clinical Nutrition and Gastroenterology
- Diet, Metabolism, and Disease
- Colorectal Cancer Screening and Detection
- Reconstructive Surgery and Microvascular Techniques
- Bariatric Surgery and Outcomes
- Pancreatitis Pathology and Treatment
- Pathogenesis and Treatment of Hiccups
- Gastric Cancer Management and Outcomes
- Acupuncture Treatment Research Studies
- Dysphagia Assessment and Management
- Genetic factors in colorectal cancer
- Inflammatory Bowel Disease
- Diabetes and associated disorders
- Respiratory Support and Mechanisms
- Clostridium difficile and Clostridium perfringens research
- Respiratory and Cough-Related Research
- Celiac Disease Research and Management
- Bone fractures and treatments
Medical University of Graz
2012-2025
Graz University Hospital
2012-2023
University of Graz
1997-2012
University of Vienna
1998-2003
Mayo Clinic
1998
Baylor University Medical Center
1990
Baylor University
1989
Berufsgenossenschaftliche Unfallklinik Ludwigshafen
1984-1988
The purpose of these studies was to gain insight into the pathophysiology pure osmotic diarrhea and caused by carbohydrate malabsorption. Diarrhea induced in normal volunteers ingestion polyethylene glycol (PEG), which is nonabsorbable, not metabolized colonic bacteria, carries no electrical charge. In PEG-induced diarrhea, (a) stool weight directly correlated with total mass PEG ingested; (b) contributed 40-60% osmolality fecal fluid, remainder being other solutes either dietary,...
Increasing interest is focusing on the role of intestinal tone, distensibility, and mechanosensation in genesis abdominal symptoms. Experimental approaches usually feature balloon distension bowel with measurements perception, compliance and/or elastance; however, methodologies are standardized incompletely. We examined reproducibility repeated assessments sensory basal elastance rectum during distension. also evaluated response to inflations that varied regard control pressure or volume,...
The optimal management of patients with reflux-associated laryngitis is unclear. We performed a placebo-controlled crossover trial in proven reflux disease and associated to determine the effect pantoprazole gain information on natural course disease.Sixty-two consecutive non-smoking hoarseness were examined. Scores respect larynx for subjective complaints determined 24-h pH-metry assess acid lower oesophagus pharynx was performed. Patients pathologic given chance enter double-blinded...
The major purpose of this research was to gain insight into the effect carbohydrate malabsorption on fecal water output. To do we measured daily output total carbohydrate, reducing sugars, and organic acids (a product bacterial fermentation). Normal subjects were studied in their native state when diarrhea induced by mechanisms that did not involve malabsorption. Patients with syndrome also studied. We concluded that: (a) Excretion its breakdown products can be expressed as a single number...
Background and aims Recent publications have found that the CC genotype of DNA variant −13910 T/C upstream LCT gene is associated with lactase non-persistence. We therefore compared value testing for this (DNA test) lactose hydrogen breath test (H2 test), which clinical standard diagnosis Patients methods One hundred twenty-three consecutive patients suspected malabsorption were tested presence by polymerase chain reaction-restriction fragment length polymorphism analysis. These also...
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range gastrointestinal non‐gastrointestinal conditions. Diagnosis can be challenging requires systematic well‐structured approach. If the initial investigation for structural, toxic metabolic disorders is negative, digestive motility gut‐brain interaction should assessed. United European Gastroenterology (UEG) Society Neurogastroenterology Motility (ESNM) identified need an updated, evidence‐based clinical guideline...
Summary Background : The effects of lactulose and polyethylene glycol on colonic transit are poorly established. Aim: To assess the these laxatives in normal subjects. Methods Colonic (mean residence time, cumulative counts stool, remaining proximal or distal colon) was measured scintigraphically subjects second third day a 3‐day ingestion 67–134 g/day lactulose, 59 glycol. Results At similar stool weight (lactulose: 653 ± 120 g/day; glycol: 522 66 g/day), significantly slower during 99 when...
The aim of the study was to assess (quantitatively) colonic hydrogen absorption. Hydrogen volumes in flatus and breath were measured over periods six hours normal subjects during fasting after ingestion non-absorbable carbohydrate lactulose simulate effect fermentable dietary fibres. If less than 76 ml/6 h accumulated colon then all it absorbed, as suggested by intercept regression line correlation between lactulose. As total volume increased, efficiency absorption decreased from 90% 20%....
Summary Background Incomplete resorption of fructose results in increased colonic hydrogen production and is a frequent cause abdominal symptoms. The only treatment available diet. Aim To study whether orally administered xylose isomerase ( XI ), an enzyme that catalyses the reversible isomerisation glucose fructose, can decrease breath excretion patients with malabsorption. Methods Patients received 25 g 100 mL water together either placebo or capsules. Primary endpoint was reduction...
<b><i>Introduction:</i></b> There is no evidence that a positive breath test good predictor of the success carbohydrate-restricted diet. Our objective was to investigate whether patients in whom lactose intolerance (LIT) or fructose (FIT) diagnosed by validated symptom measurement respond <b><i>Methods:</i></b> Patients referred for evaluation LIT FIT underwent hydrogen/methane testing (malabsorption test) and with adult Carbohydrate Perception...
Background —Stimulation of sensory nerves with capsaicin regulates ion transport in the small intestine animal experiments. Aim —To investigate whether that are stimulated by administration influence fluid and electrolyte absorption human jejunum vivo. Method —Intestinal perfusion studies were performed 12 healthy subjects using a four lumen tube proximal occlusion balloon plasma-like solution. After an initial control period, 5 (n = 3), 10 8), or 50 1) μg/ml was added to perfusate, this...