A5014540824- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Osteoarthritis Treatment and Mechanisms
- Medical and Biological Sciences
- Healthcare Systems and Public Health
- Systemic Sclerosis and Related Diseases
- Inflammatory mediators and NSAID effects
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Systemic Lupus Erythematosus Research
- Psoriasis: Treatment and Pathogenesis
- Neurological Disorders and Treatments
- Gout, Hyperuricemia, Uric Acid
- Bone health and osteoporosis research
- Genetic and Kidney Cyst Diseases
- Autoimmune and Inflammatory Disorders Research
- Vascular Malformations and Hemangiomas
- Hip and Femur Fractures
- Parathyroid Disorders and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bone Metabolism and Diseases
- Gastroesophageal reflux and treatments
- Viral Infections and Immunology Research
- Helicobacter pylori-related gastroenterology studies
Institute of Public Health Zadar
2019-2025
Institute for Advanced Medical Research
2020-2024
Consultative and Diagnostic Center
2024
Ministry of Health of the Russian Federation
2015-2024
Lomonosov Moscow State University
2020
Ministry of Health
2019
Khabarovsk Scientific Research Institute of Epidemiology and Microbiology
2015
By the end of first decade 21st century, spondyloarthritis studies have accumulated a certain number of terms that are obsolete, but used by physicians in their everyday speech, on one hand, and great variety different definitions, other hand. In January 2014, organizational meeting Expert Group on Spondyloarthritis, Association Rheumatologists Russia, decided its primary task should be to order terminology used this area. The authors primarily collected terms, which had been already medical...
Gout is the most common inflammatory joint disease, related to microcrystalline arthritis. With improper or inadequate treatment, gout can lead disability. A patient with a misdiagnosis of tophaceous described in whom differential diagnosis neoplasm was performed. As result additional examination, giant cell tenosynovial tumor second finger right hand discovered.
Rheumatic pathology as a socially significant group of chronic immune-inflammatory diseases is pressing problem in modern rheumatology and orthopedics. Its etiopathogenesis has not been fully studied, late detection the disease leads to early loss ability work subsequent disability patients. The definition "rheumatic orthopedics" arose at intersection two disciplines – first rheumatic orthopedic department was established middle last century V. A. Nasonova Research Institute Moscow....
The paper gives the recommendations for assessment of disease activity and functional status in patients with ankylosing spondylitis clinical practice, which have been developed by experts, taking into account international Russian experience managing these patients.
A meeting of the Expert Council on September 9, 2023 considered last challenges in treatment osteoarthritis (OA) including OA comorbid patients. Leading experts rheumatology, traumatology and other relevant disciplines participated meeting. The key goal was discussion potential application a combination undenatured (native) type II collagen, methylsulfonylmethane, boswellic acids, vitamins C D (Artneo complex) as part complex therapy. concluded that Artneo for stage I–III knee patients is...
Aim to identify outdated terms and make changes the terminology of spondyloarthritis.At first stage work, divided into two categories: "outdated" definitions that need be improved or unified. Subsequently, each member Expert Group Spondyloarthritis at Association Rheumatologists Russia (ExSpA) presented by its own definition designated term agreed with previous term. At next stage, existing were put together. After discussion, experts left a scored least 2/3 votes. The special opinion was...
Rheumatoid arthritis (RA) is the most frequent immunoinflammatory (autoimmune) rheumatic disease characterized by chronic erosive and systemic damage to internal organs. The data obtained in course of basic research on deciphering mechanisms action methotrexate (MT) materials numerous randomized placebocontrolled trials, observational studies national registries have strengthened position MT as “gold standard” RA pharmacotherapy a key component “Treatment Target” strategy. This was basis for...
The paper gives recommendations for the drug therapy of axial spondyloarthritides, which have been developed by the Spondyloarthritis Study Group Experts. describe patient management tactic in most common clinical situations, is aimed at maximizing efficacy and safety treatment.
Giant cell arteritis (GCA) and polymyalgia rheumatica (RPM) are immune-mediated rheumatic disease (IMRDs), which typically develop in people over 50 years of age. Currently, GCA PMR considered within a single complex autoimmune-autoinflammatory pathology, defined as “GCA-PMR spectrum disease”. This was reflected the development general recommendations for pharmacotherapy framework “treat-to-tar get” strategy, although specific approaches to treatment patients with RPM differ depending on...
To analyze the state-of-the-art of consulting medical care to Russian patients with glucocorticoid-induced osteoporosis (GCOP) or its risk.This GLUCOST study was organized and conducted by Association Osteoporosis. A total 1129 chronic inflammatory diseases, who had been taking oral glucocorticosteroids (OGCSs) a long time (3 months more), were examined. The filled out an anonymous questionnaire on their own. Whether measures taken diagnose, prevent, treat GCOP complied main points clinical...
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The paper provides guidelines for the use of tumor necrosis factor- α (TNF- ) inhibitors in treatment patients with axial spondyloarthritis (axSpA), including ankylosing spondylitis. It gives data on efficacy TNF- non-radiographic axSpA. By using international and Russian guidelines, authors lay down indications this therapy criteria evaluation its efficiency safety.
Non-steroidal anti-inflammatory drugs (NSAIDs) are most popular medications for the treatment of pain in common musculoskeletal diseases such as osteoarthritis (OA) and non-specific low back (LBP). However, factors affecting effectiveness these have not been determined fully. Aim: to identify NSAIDs patients with OA LBP. Materials methods. An observational study was conducted evaluate a 2-week course LBP real clinical practice. The group consisted 3604 (60.6% women 39.4% men, mean age...
The literature virtually lacks the results of investigations aimed to study clinical picture ankylosing spondylitis (AS) in real practice rheumatologists Russia. At same time, these may give information on not only epidemiological aspects disease, but also a variety its presentation, social importance, allow evaluation efficiency therapy, and plan system further health care costs. Subjects methods. In early 2015, cross-sectional multicenter non-interventional trial EPICA2 was conducted...
The paper gives the draft guidelines elaborated by Expert Spondyloarthritis Diagnosis and Treatment Group order of Association Rheumatologists Russia. include essentials how to use nonsteroidal anti-inflammatory drugs in axial spondyloarthrititides, including ankylosing spondylitis, contain instructions for long they should be administered, describe possible patient management tactics most common clinical situations a preferential algorithm evaluating efficiency safety treatment.
The paper gives the definition of remission in axial spondyloarthritides (axSpA), which has been developed by Spondyloarthritis Study Group Experts. work used Delphi technique. At stage 1, based on analysis data available literature and their own clinical experiences, experts proposed some variants ways its evaluation patients with axSpA. Stage 2, definitions that had received at least 80% votes via anonymous voting were selected adopted without further discussion. Those an equal number...
The paper presents the results of Osteoarthritis (OA) Expert Council held on September 8, 2019, which was attended by Russian and foreign specialists. experts considered pharmacological treatment options for OA. expert meeting resolution states that patients with OA should be based an individual assessment patient a modern evidence base therapy efficacy. Treatment is principles evidence-based medicine requires integrated approach need SYSADOAs prescription. Combined drugs therapeutic dosages...
Objectives. This study is a part of GLUKOST hosted and organized by the Russian Association Osteoporosis. The aim was to estimate incidence risk factors fractures in patients with chronic inflammatory diseases. Materials Methods. A specially designed questionnaire introduced diseases different regions Russia. included 2342 aged 18 89 years (mean age 53.02 ± 14.03 years, 591 men 1181 women). were allocated into two groups: group 1 (n = 1402) - never prescribed oral long acting glucocorticoids...
in 3 mL on patients with knee osteoarthritis (OA) a multicenter prospective study. 79 outpatients (predominantly females 81.0%) from 5 RF constituent territories primary tibiofemoral KellgrenLawrence score grade II or III OA, 40 mm pain intensity during walking visual analogue scale (VAS), requiring NSAIDs intake (for at least 30 days months prior to enrollment) were included into the study after signing informed consent form. Mean age was 60.38.7 years, mean BMI 29.24.7 kg/m2, disease...
The paper provides a detailed description of the two cases one rarest diseases - Gorham-Stout syndrome. This syndrome is accompanied by massive osteolysis various sites bone tissue. literary review done. isolated separate parts non-malignant process, and it goes without abnormalities its functions. combination with chylothorax an unfavorable process. treatment this disease possible only calcitonin or bisphosphonates.
Objective. To estimate arterial rigidity parameters from noninvasive arteriographic readings in patients with gout and essential hypertension (EH). Subjects methods. One hundred twenty-eight EH were examined by arteriography (Tensio Clinic TL1 arteriograph, Tensio Med, Hungary). Results. In gout, central artery stiffness is higher than that healthy individuals characterized the increases pulse wave velocity augmentation index. Impaired suggests these changes play a prominent role...
Objective : to investigate in a multicenter study relationship between type 2 diabetes mellitus (DM) and clinical manifestations of osteoarthritis (OA). Material methods . The involved 767 patients aged 40–75 years with confirmed diagnosis stage I–III knee OA who had signed an informed consent form. mean age was 57.9±9.6 years, body mass index (BMI) 30.8±6.4 kg/m2 median duration disease 5 [2; 11] years. An individual record card filled out for each patient, it contained anthropometric...
BACKGROUND: Uric acid can affect many metabolic processes in the human body. In recent decades, great importance has been given to increased levels of uric — hyperuricemia. Hyperuricemia proven be an independent risk factor for development cardiovascular, renal and diseases, not just their marker, as had previously ben considered. AIM: To determine incidence hyperuricemia at primary outpatient stage, well assess prevalence comorbid pathology among patients with Khabarovsk Territory....