A5003212949- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Diverticular Disease and Complications
- Genetic factors in colorectal cancer
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Gastrointestinal Bleeding Diagnosis and Treatment
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Radiomics and Machine Learning in Medical Imaging
- Autoimmune and Inflammatory Disorders
- Global Healthcare and Medical Tourism
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Anesthesia and Sedative Agents
- Appendicitis Diagnosis and Management
- AI in cancer detection
- Soft tissue tumor case studies
- Eosinophilic Esophagitis
- Intestinal and Peritoneal Adhesions
State Scientific Center of Coloproctology
2016-2025
Russian Medical Academy of Continuous Professional Education
2021-2025
Ministry of Health of the Russian Federation
2020-2023
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AIM: to identify risk factors for perforation during colorectal ESD early colon cancer.PATIENTS AND METHODS: the study included 61 patients with cancer who underwent in 2018–2023. Perforation was defined as a deep muscular layer defect down serosa its preservation without connection free peritoneal cavity. Clinical ESD, including age, gender, tumor morphology, size, location, procedure time, were analyzed.RESULTS: mean specimen size 20.0 (1.50–2.80) mm. The overall en bloc resection rate...
AIM: to develop a unified algorithm of bowel cleansing for the colonoscopy, distinguish main criteria qualitative colonoscopy and rules protocol in patients after colorectal surgery.PATIENTS AND METHODS: we analyzed available literature data our own experience endoscopic examination with operated colon.RESULTS: patient preparation execution different types surgical interventions on colon were developed.CONCLUSION: it is necessary raise awareness surgeons oncologists about peculiarities...
AIM: the aim of this article was to demonstrate possibilities using TEM for large (more than 5.0 cm) and giant 8.0 rectal adenomas.PATIENTS AND METHODS: more 1000 transanal endoscopic microsurgery procedures were performed in 2011- 2023. Three groups distinguished according tumor size: Group I — tumors less cm; II 5.0–8.0 cm (large); III (giant).RESULTS: final analysis included 600 patients. with sizes 465 (77.5%) adenomas 120 (20%) The group tumors, larger cm, 15 (2.5%) In (less cm), R0...
Aim : to identify risk factors for neoplasms recurrence removed by endoscopic mucosal resection (EMR). Patients and methods the single-center retrospective observational study included 207 patients with 260 benign colon neoplasms. There were 95 (45.9%) males 112 (54.1%) females. The median age of was 67 (27-80) years. results obtained assessed using following criteria: morbidity rate, complication type, hospital stay, tumor site, number in colon, lateral growth, fragmentation technical...
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AIM: to estimate the effectiveness of a medical decision support system based on artificial intelligence in endoscopic diagnosis benign tumors during tandem study.PATIENTS AND METHODS: from October December 2023, single-center comparative study “ArtInCol” was done. The first stage traditional colonoscopy under sedation, second one — using AI. A pairwise comparison main indicators made.RESULTS: primary endpoint, polyp detection rate (PDR) group 40.6% vs 56.4% AI group, p = 0.0001 (RR 1.39;...
AIM: to assess results of endoscopic submucosal dissection (ESD) for colon neoplasms due lesion site. PATIENTS AND METHODS: One-hundred thirteen patients (66 females, aged 65,7±11,0 years) with which underwent ESD one year (January 2017 – January 2018) were included in the study. All divided two groups depending on The first group lesions caecum, ascending and proximal third tranverse colon, second other parts intraperitoneal part rectum. preoperative tests including colonoscopy, gastroscopy...
AIM: transanal endomicrosurgery (TEM) is the standard for organ-preserving treatment of patients with large adenomas and early rectal cancer. The advantage TEM in comparison other methods tumors low frequency R1 resections fragmentation, which procudes a level local recurrences. Endoscopic submucosal dissection (ESD) new technology superficial rectum tumors. This systematic review meta-analysis compared safety efficacy ESD vs adenoma colorectal PATIENTS AND METHODS: literature search data...
Aim: to identify the risk factors for conversion of endoscopic submucosal dissection abdominal surgery. Patients and methods : prospective cohort study included 405 patients: 166 (40.9%) males 239 (59.1%) females. The median age was 66 (59; 72) years old; patients underwent colorectal epithelial neoplasms. Results: size removed neoplasms 3.0 (2.4; 4) cm, tumor en bloc in 324/363 (89.2%) cases; R0 resection margins were detected 218/324 (67.3%) cases. Significant were: ≥ 3.2 cm (OR 2.9, 95%...
AIM: to estimate the implementation of original method that uses artificial intelligence (AI) detect colorectal neoplasms. MATERIALS AND METHODS: we selected 1070 colonoscopy videos from our archive with 5 types lesions: hyperplastic polyp, serrated adenoma, adenoma low-grade dysplasia, high-grade dysplasia and invasive cancer. Then 9838 informative frames were selected, including 6543 Lesions annotated obtain data set was finally used for training a convolution al neural network (YOLOv5)....
Colon capsule endoscopy is a minimally invasive method for diagnosis of inflammatory and neoplastic diseases the gastrointestinal tract. This study can be used as screening detecting colon cancer, in patients who either refused colonoscopy, or it contraindicatedfor one reason another. The diagnostic efficiency by using second-generation significantly increased.
OBJECTIVE: to compare the immediate and long-term results of endoscopic mucosal resection with a circular incision (C-EMR) submucosal dissection (ESD) in treatment patients large benign epithelial neoplasms colon. PATIENTS AND METHODS: prospective randomized comparative study was conducted from November 2020 July 2022, included 103 colon ranging size 20 30 mm. The C-EMR method used 52, ESD - 51 patients. RESULTS: removal tumor by required statistically significantly less time, compared – 60...
Juvenile polyposis syndrome (JPS), a rare disease with an autosomal dominant mode of inheritance, which is characterized the presence multiple polyps in various parts gastrointestinal tract, mainly colon. The detection adenomatous patients JPS, addition to juvenile ones, significantly complicates differential diagnosis familial polyposis, it necessary perform radical surgery — proctocolectomy. Only 40-60% cases, pathogenic variants SMAD4 and BMPR1A genes can be identified, each its own...
AIM: to compare the diagnostic informativeness of mucosal dye spraying (chromoendoscopy) (CE) and virtual chromoendoscopy (VCE) in detecting dysplasia patients with a long history ulcerative colitis (UC).MATERIALS AND METHODS: systematic review meta-analysis studies comparing results use CE VCE for diagnosis colitis-associated was performed. The following indicators were evaluated: frequency endoscopically detected endoscopic among total number identified lesions. statistical analysis...
AIM: to estimate the efficacy and safety of outpatient polypectomy epithelial benign tumors colon.PATIENTS AND METHODS: prospective cohort study included 809 patients with colon polyps removed by cold loop (CSP), hot (HSP) injection (HSP + injection). Intraand postoperative complications were assessed.RESULTS: a total 2115 2–20 mm (0.5 [0.4; 0,7] mm) removed. No intraoperative occurred. Prophylactic clipping was performed in 6,5% cases significant higher rate for larger neoplasms: 10–20 —...
Background. PeutzJeghers syndrome (PJS) is a rare hereditary characterized by the growth of hamartomatous polyps in gastrointestinal tract, perioral pigmentation and an increased risk malignant neoplasms. The caused pathogenic variant STK11 gene. Aim. To assess clinical picture treatment Russian patients with PJS. Materials methods. A retrospective analysis 30 from 25 families established diagnosis PJS who were Ryzikh State Scientific Center for Coloproctology 2011 to 2021 was carried out....
AIM: to evaluate the impact of dietary compliance in bowel cleansing for colonoscopy on quality procedure. PATIENTS AND METHODS: one thousand patients who scheduled diagnostic were included prospective observation study. The preparation was assessed using Boston scale. Neoplasms detected and endoscopically evaluated. optical verification tumors used calculate indicators identified adenomas polyps (ADR PDR). RESULTS: by Scale 6 (6; 8) points. One hundred eight (19.8%) did not follow...
Introduction . Granular cell tumor (GCT, synonym – Abrikossoff’s tumor) is a benign neoplasm of neuroectodermal differentiation from epithelioid cells originating Schwann’s cells, with characteristic sign the presence lysosomal granules in cytoplasm. 5–10% GCTs are found gastrointestinal tract, most frequent localization esophagus, large intestine (the right colon) and perianal zone. Most often, occurs at age 40–60 years, women. As rule, single, but it can be multiple associated various...
BACKGROUND: endoscopic submucosal dissection (ESD) is a modern effective method for patients with benign epithelial tumors and early colorectal cancer.The use of such technique ESD as tunnel (‘pocket’) – creation under tumor creates conditions improving the surgical specimen qualityand reducingfragmentationrate.Aim: to study effectiveness safety (TESD) in comparison classical (CESD) adenomas cancer.MATERIALS AND METHODS: literature search meta-analysis were performed accordance PRISMA...
AIM to show on the results of our study influence quality preparationfor videocapsule endoscopy (VCE) accuracy diagnosis diseases small and large intestine. MATERIALS AND METHOD. During period from September 2014 December 2016, a was performed 100 patients treatment at State Scientific Center Coloproctology. Final data processing carried out based survey 96 (52 men 44 women aged 18 78 years). To adequately prepare for study, we used specific scheme with use «splitdose» intestinal cleansers...
In the review data concerning modern methods of endoscopic treatment colonic strictures are presented. Relevance this problem, reasons for development, clinical picture and procedures presented in detail. The analysis Russian foreign literature with an assessment effectiveness feasibility various has been done. Despite variety ways existing stricture’s treatment, there still no evidence-based on efficiency safety approaches. Thus, a number unresolved topical issues that require further research.
Endoscopic submucosal dissection (ESD) is a perspective method of organ-sparing treatment benign colon tumors.The study included 1.000 patients with neoplasms who underwent ESD between October 2016 and 2021. All surgeries were performed under intravenous sedation.Mean dimension tumors was 3.4 cm, median surgery time - 51 (31; 101) minutes. Conversion endoscopic approach occurred in 7.6% cases. The main cause conversion unsatisfactory lifting injection process. Incidence en bloc R0 resections...