A5005046140- Pharmacogenetics and Drug Metabolism
- Eosinophilic Esophagitis
- Human Health and Disease
- Healthcare Systems and Public Health
- Long-Term Effects of COVID-19
- Eicosanoids and Hypertension Pharmacology
- Influenza Virus Research Studies
- Esophageal Cancer Research and Treatment
- COVID-19 Clinical Research Studies
- Inflammatory mediators and NSAID effects
Chita State Academy of Medicine
2020-2022
Aims . To study the CYP2C19(681A/G) polymorphism among population of Trans-Baikal Territory in comparison with data other regions Russia and world. Materials methods. The involved 132 people (81 women 53 men). median age was 47 (18; 72) years. Genotyping 681G/A polymorphic locus CYP2C19 gene performed by polymerase chain reaction. Results. prevalence CYP2C19(681G/G) 105 (79.6%), CYP2C19(681G/A) — 25 (18.9%) CYP2C19(681A/A) 2 participants (1.5%). Allele A position 681 found 14.2%. is less...
Aim. To assess inflammatory markers and organ dysfunction in patients with severe influenza A (H1N1) virus-associated pneumonia. Materials Methods. The study included 50 (median age 47 (38-62) years, 24 males 26 females) We analysed the clinicopathological data as well complete blood count biochemical profile. Organ was assessed using SOFA qSOFA scales. Results. prevalence of multiple syndrome pneumonia 46% (23/50 patients). Patients frequently suffered from insufficient oxygenation,...