A5050831801- Oral microbiology and periodontitis research
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Medical and Biological Sciences
- COVID-19 Clinical Research Studies
- Otolaryngology and Infectious Diseases
- Oral Health Pathology and Treatment
- Probiotics and Fermented Foods
- Respiratory and Cough-Related Research
- Phosphorus and nutrient management
- Antibiotic Resistance in Bacteria
- Intramuscular injections and effects
- Dental Health and Care Utilization
- Dental Erosion and Treatment
- Oral health in cancer treatment
- Long-Term Effects of COVID-19
- Dental Education, Practice, Research
- Periodontal Regeneration and Treatments
- Dysphagia Assessment and Management
- Salivary Gland Disorders and Functions
- Orthodontics and Dentofacial Orthopedics
- Antibiotic Use and Resistance
- Tryptophan and brain disorders
- Temporomandibular Joint Disorders
- Pneumonia and Respiratory Infections
Ministry of Health of the Russian Federation
2021-2025
Moscow State University of Medicine and Dentistry
2021-2024
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global healthcare, underscoring importance of exploring virus's effects on infected individuals beyond treatments and vaccines. Notably, recent findings suggest that can infect gut, thereby altering gut microbiota. This study aimed to analyze microbiota composition differences between patients experiencing mild severe symptoms. We conducted 16S rRNA metagenomic sequencing fecal samples from 49 43 cases upon...
The majority of metagenomic studies are based on the study bacterial biota. At same time, COVID-19 pandemic has prompted interest in both individual fungal pathogens and communities (i.e., mycobiome) as a whole. Here, this work, we investigated human gut mycobiome during COVID-19. Stool samples were collected from patients at two time points: admission to hospital (the first point) discharge second point). results revealed that Geotrichum sp. is more represented group with Therefore,...
Introduction The new coronavirus disease, COVID-19, poses complex challenges exacerbated by several factors, with respiratory tissue lesions being notably significant among them. Consequently, there is a pressing need to identify informative biological markers that can indicate the severity of disease. Several studies have highlighted involvement proteins such as APOA1, XPNPEP2, ORP150, CUBN, HCII, and CREB3L3 in these lesions. However, lack information regarding antibodies human body, which...
Antimicrobial resistance poses a serious threat to global public health. The COVID-19 pandemic underscored the need monitor dissemination of antimicrobial genes and understand mechanisms driving this process. In study, we analyzed changes oropharyngeal fecal resistomes patients with undergoing therapy in hospital setting. A targeted sequencing panel 4,937 was used comprehensively characterize resistomes. Our results demonstrated that resistome is homogeneous, showing low variability over...
Relevance. The COVID-19 pandemic caused by the SARS-CoV-2 virus has demonstrated critical importance of understanding mechanisms transmission and finding effective methods prevention. Particular attention been paid to role oral hygiene, as cavity serves a major route transmission. Studies show that composition microbiota can influence course outcome disease. Therefore, there is need study effects antiseptics on microbiome, which may offer new opportunities for prevention treatment this...
Gastroesophageal reflux disease (GERD) is a common chronic leading to spontaneous and regular retrograde flow of gastric and/or duodenal contents into the esophagus. Reflux oral cavity refers extraesophageal presentation disease, which, in absence timely treatment, can result erosion dental hard tissue (EDHT) through repeated exposure acidic contents. EDHT are non-carious lesions tissues (mainly enamel, some cases dentin), induced by chemical reaction involving acids, which results...
Magnesium alloys have emerged as a promising materials for temporary implants in medical applications due to their favorable biomechanical properties and biocompatibility. Their natural degradation within the body minimizes need surgical removal, making them particularly attractive use orthopedics, dentistry, veterinary medicine. However, formation of gas cavities during poses significant challenges, adversely affecting mechanical stability healing outcomes. This study aims develop...
Numerous attempts have been made in the periodical publications on history of «Moscow State University Medicine and Dentistry named after A.I. Evdokimov» to trace its roots back First Moscow School. founded by I.M. Kovarsky 1892, as Institute (which, a result various reorganizations had renamed MSMSU) was established school building. This reasoning does not seem entirely convincing, however, analyzing some facts from School biography founder Kovarsky, authors conclude that there is...
Relevance. The COVID-19 pandemic posed significant challenges not only to society and the healthcare system but also dental specialists. Hospitalization of patients with chronic generalized periodontitis associated course is known adversely affect overall condition create risk for disease severity aggravation. study inflammatory periodontal correlation relevant. Purpose . aimed determine features (IPD) in after moderate by determining oral fluid (OF) blood serum (BS) biochemical parameters....
Introduction . Currently, dentists are increasingly detecting changes in the temporomandibular joint patients with chronic inflammatory periodontal disease. Aim of study To carry out a comprehensive dynamic assessment (TMJ) condition and registration regional blood flow using two-dimensional ultrasound scanning to improve efficiency diagnostics diseases. Materials methods The included 2 groups patients: group 1 (control) consisted 20 volunteers aged 20–25; Group 52 people 25–45 years...
<title>Abstract</title> Background The global healthcare landscape has changed dramatically as a result of the COVID-19 pandemic caused by SARS-CoV-2. In addition to focusing on treatments and vaccines, it is crucial investigate effects virus infected individuals. Recent studies have discovered that SARS-CoV-2 can infect gut, affecting gut microbiota revealing new aspect virus. This study examined differences in composition between patients with severe mild conditions. Methods this study, we...
Aim. To study overall drug resistance genes (resistome) in the human gut microbiome and changes these during COVID-19 in-hospital therapy. Materials methods. A single-center retrospective cohort was conducted. Only cases with laboratory-confirmed SARS-CoV-2 RNA using polymerase chain reaction oro-/nasopharyngeal swab samples were subject to analysis. The patients a documented history of or current comorbidities hepatobiliary system, malignant neoplasms any localization, systemic autoimmune...
<h3></h3> Конец XIX века ознаменовался в России реформой зубоврачебного образования, частности, открытием частных зубоврачебных школ, сменивших систему подготовки дантистов кабинетах наставников. Как свидетельствуют отчеты заведующего Первой московской зубоврачебной школой И.М. Коварского, за первые 10 лет существования школы окончить ее смогли лишь около половины поступивших: одной из причин этого могла быть весьма высокая стоимость обучения. Для помощи малообеспеченным учащимся школе были...
Introduction. The use of remdesivir in patients with the new coronavirus infection COVID-19 is known to improve prognosis disease. But there not enough data on efficacy and safety from Russia. Aim. To evaluate COVID-19. Materials methods. A comparative prospective study was conducted two parallel groups. enrolled 300 diagnosed (grade 1–3 severe pneumonia according CT scan), who were divided into groups (n = 150 each) prescription remdesivir. Treatment assessed by recording cases disease...
Aim. To identify features of the taxonomic composition oropharyngeal microbiota COVID-19 patients with different disease severity. Materials and methods. The study group included 156 hospitalized confirmed diagnosis in clinical medical center Yevdokimov Moscow State University Medicine Dentistry between April June 2021. There were 77 mild pneumonia according to CT (CT1) 79 moderate severe (CT2 CT3). Oropharyngeal swabs taken when patient was admitted hospital. Total DNA isolated from...
Aim . To evaluate the results of surgical treatment patients with moderate chronic periodontitis different dental pulp status by determining sRANKL, OPG and FGF-2 in mixed saliva dynamic densitotomometry data. Materials methods Surgical 24 was performed. Three months before operation, according to indications, endodontic examined teeth performed some patients. Depending on pulp, were divided into two groups: I – vital teeth, II after treatment. Before surgery, all underwent clinical...