Esra Nur Tola

ORCID: 0000-0002-4606-9965
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About
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Research Areas
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Pregnancy and preeclampsia studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Sperm and Testicular Function
  • Birth, Development, and Health
  • Maternal and Perinatal Health Interventions
  • Prenatal Screening and Diagnostics
  • Endometriosis Research and Treatment
  • Reproductive System and Pregnancy
  • Maternal and fetal healthcare
  • Sexual function and dysfunction studies
  • Pelvic floor disorders treatments
  • Ovarian cancer diagnosis and treatment
  • Gestational Diabetes Research and Management
  • Reproductive Health and Technologies
  • Toxoplasma gondii Research Studies
  • Reproductive Health and Contraception
  • Gynecological conditions and treatments
  • Cytomegalovirus and herpesvirus research
  • Anorectal Disease Treatments and Outcomes
  • Kruppel-like factors research
  • Uterine Myomas and Treatments
  • Preterm Birth and Chorioamnionitis
  • Pelvic and Acetabular Injuries

Istanbul Medipol University
2020-2025

Süleyman Demirel University
2013-2019

Isparta University of Applied Sciences
2015-2018

İstanbul Eğitim ve Araştırma Hastanesi
2018

Sağlık Bilimleri Üniversitesi
2018

Suleyman Demirel University
2014

Objective: To investigate relationships between spontaneous abortion and complete blood count inflammation markers their role in predicting abortion.Methods: This study was conducted at Department of Obstetrics Gynecology January 2012 2017. A total 570 participants, 325 diagnosed with 245 control patients who underwent timely births were included into our study. The white cell (WBC), neutrophil (N), lymphocyte (L), neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV)...

10.12669/pjms.346.15939 article EN Pakistan Journal of Medical Sciences 2018-10-25

Objective: To evalute the association between Type-D personality and in vitro fertilization (IVF) success unexplained infertile women. Methods: This was a cross-sectional study conducted at IVF unit of tertiary center September 2017 - December 2019. The 21 items Beck Depression Inventory (BDI-21) 14 Scale (DS14) were noted from 256 women undergoing an cycle. Results: Paternal educational level clinical pregnancy lower depression more prevalent Type-Ds than non-Type-Ds. There positive...

10.12669/pjms.41.3.9966 article EN cc-by Pakistan Journal of Medical Sciences 2025-02-21

Spontaneous uterine rupture is a life-threatening obstetrical emergency carrying high risk for the mother and fetus. in early pregnancy very rare complication it occurs usually scarred uterus. Uterine anomalies are one of reasons spontaneous unscarred pregnancy. Obstetricians must consider this diagnosis when pregnant patient presented with acute abdomen We present case at 12 weeks gestation 24-year-old multigravida who had anomaly presenting as an abdomen. Our preoperative was ectopic...

10.1155/2014/967386 article EN cc-by Case Reports in Obstetrics and Gynecology 2014-01-01

Abstract Aim To compare the outcomes of intracytoplasmic sperm injection (ICSI) fresh and cryopreserved obtained via microdissection testicular extraction (micro‐TESE) in cases non‐obstructive azoospermia (NOA). Methods A total 147 patients with NOA who underwent micro‐TESE viable at Istanbul Medipol In Vitro Fertilization unit were recruited retrospectively. The divided into two groups depending on used (fresh or frozen–thawed) for ICSI: group ( n = 93) ICSI cycles spermatozoa...

10.1111/jog.16298 article EN Journal of Obstetrics and Gynaecology Research 2025-04-24

The purpose of our study was to evaluate whether the inflammatory parameters complete blood count (CBC), including white cell (WBC), neutrophil-to-lymphocyte-ratio (NLR), platelet-to-lymphocyte-ratio (PLR), and mean platelet volume (MPV), had potential roles in etiopathogenesis unexplained infertility (UI) among nonobese women. We also aimed investigate there could be an association between these markers vitro fertilization (IVF) success women with UI. This a retrospective clinical trial,...

10.1016/j.tjog.2018.02.019 article EN cc-by-nc-nd Taiwanese Journal of Obstetrics and Gynecology 2018-04-01

Purpose: Type D personality—defined as the presence of two personality characters, namely negative affectivity (NA) and social inhibition (SI)—is associated with various disorders. The 14-item Scale (DS14), which consists NA SI subscales, can be used for detection personality. aim our study was to investigate association depression infertility in women.Method: A total 324 women, 168 primary unexplained infertile women (92 patients undergoing vitro fertilization (IVF) treatment 76...

10.1080/0167482x.2019.1573224 article EN Journal of Psychosomatic Obstetrics & Gynecology 2019-02-20

General anesthesia is used in most vitro fertilization (IVF) clinics for oocyte pick-up (OPU), however, there no consensus on type of anesthetic agent use among clinicians performing OPU. Therefore, we aimed to evaluate the effects propofol, ketamine, or combination propofol and ketamine (P + K) OPU IVF outcome. Three hundred thirty three women (n = 333) undergoing treatment were retrospectively included evaluated groups depending whether they received 217), 60), P K 56) during Baseline...

10.1016/j.tjog.2019.07.016 article EN cc-by-nc-nd Taiwanese Journal of Obstetrics and Gynecology 2019-09-01

Oxidative stress has been proposed as a potential trigger in the etiopathogenesis of polycystic ovary syndrome-related infertility. Thiol/disulphide homeostasis, recently identified oxidative marker, is one antioxidant mechanism humans with critical roles folliculogenesis and ovulation.To investigate follicular fluid thiol/disulphide homeostasis syndrome to determine its association vitro fertilization outcome. The study procedures were approved by local ethics committee.Cross-sectional...

10.4274/balkanmedj.2017.1140 article EN cc-by-nc-nd Balkan Medical Journal 2018-04-03

Oxidative stress is important for promoting oocyte maturation and ovulation within the follicle through calcium ion (Ca2+) influx. The relationship between antioxidant cytosolic Ca2+ levels quality fertilisation rate in granulosa cells of patients undergoing vitro was investigated. Granulosa were collected from 33 patients. Cytosolic free ([Ca2+]i) concentration, lipid peroxidation, reduced glutathione, glutathione peroxidase measured cells. two drug protocols also examined...

10.1071/rd12144 article EN Reproduction Fertility and Development 2013-01-01

To investigate Phosphorylated adenosine monophosphate activated protein kinase (AMPK) levels in healthy pregnant women and with preeclampsia (PE).Twenty-eight mild-PE, 22 severe-PE, 30 normotensive controls were included this cross-sectional study. The serum AMPK of these patients analyzed. followed up to delivery.No statistically significant difference was found between the groups for age, gravida, parity, gestational age at time blood samples obtained (p > .05). No group mild-PE control...

10.1080/14767058.2018.1448774 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2018-03-05

Objective: Gremlin 1 and 2 regulate oocyte primordial follicle transition in animal models. The main objective of this study is to measure the blood levels women with Polycystic Ovary Syndrome (PCOS). We also aimed evaluate association these markers hormonal biochemical parameters PCOS as interrupted folliculogenesis those related metabolic dysfunction. Material methods: Fifty were diagnosed according Rotterdam criteria, thirty age-matched female controls included prospective study. along...

10.1080/09513590.2019.1566452 article EN Gynecological Endocrinology 2019-02-04

Chorioamnionitis is one of the most important maternal complications in expectant management patients with preterm premature rupture membranes (PPROM). Procalcitonin (proCT), precursor hormone calcitonin, used to differentiate bacterial infections from non-bacterial ones. The objective study was determine efficacy serum procalcitonin levels early prediction chorioamnionitis women PPROM.The conducted 76 pregnant hospitalized due PPROM at maternal-fetal medicine unit a tertiary center...

10.5114/aoms.2019.86191 article EN cc-by-nc-sa Archives of Medical Science 2019-08-20

The present study aims to evaluate the role of follicular fluid (FF) and serum (s) total oxidant status (TOS), antioxidant (TAS) oxidative stress index (OSI) on etiopathogenesis unexplained infertility (UI) intracytoplasmic sperm injection-embryo transfer (ICSI-ET) success. Twenty UI patients 20 controls with male factor undergoing an ICSI-ET cycle were recruited. FF samples aspirated from mature follicles blood collected just before oocyte retrieval stored until analysis. Embriyo quality...

10.1080/01443615.2021.1960294 article EN Journal of Obstetrics and Gynaecology 2021-11-29

To investigate liver-derived plasma protein fetuin B levels in healthy pregnant women and with intrahepatic cholestasis of pregnancy (ICP).Forty ICP 40 were included this cross-sectional study. The serum these patients analyzed. followed up to delivery.Maternal age, gravida, parity, BMI at assessment, gestational age blood sampling similar between the control groups (p > .05). However, delivery birth weight significantly lower group < Total bile acid (TBA) liver function tests higher than...

10.1080/14767058.2017.1413546 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2017-12-12

Cigarette smoking (CS) has some detrimental effects that occur via oxidative stress (OS). The aim of this work was to demonstrate the pathological and immunohistochemical CS protective a strong antioxidant alpha lipoic acid (ALA) on CS-induced genital system changes in rat model. Twenty-eight female rats were randomly allocated three groups as control, CS-exposed, CS-exposed ALA-treated. Reproductive tract organs collected for biochemical examinations. In group, OS markers increased tissues...

10.1177/0748233718755160 article EN Toxicology and Industrial Health 2018-03-28

The aim of the study was to investigate pancreatic-derived factor (PANDER) levels in healthy pregnant women and with gestational diabetes mellitus (GDM). A total 50 consecutively diagnosed GDM 30 randomly selected age-matched gestational-age-matched were included this cross-sectional study. Serum PANDER other variables analyzed. age, age at time, blood sample obtained hemoglobin A1c (HbA1c) control groups similar. body mass index (BMI), fasting glucose, insulin, homeostasis model assessment...

10.1080/09513590.2019.1599856 article EN Gynecological Endocrinology 2019-04-15

Impairment in placental angiogenesis is blamed for the etiopathogenesis of intrauterine growth restriction (IUGR).To assess genes related to biopsies pregnancies complicated by IUGR that could be aberrantly methylated and adversely affect angiogenesis.The methylation profiles soluble fms-like tyrosine kinase-1 (sFLT-1), vascular endothelial factor (VEGF), (PIGF) were evaluated using Illumina MiSeq™ System from term without preeclampsia (n = 18) healthy controls 17). DNA was isolated samples...

10.1080/14767058.2019.1671344 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2019-10-03

Günümüzde erken tanı ve tedaviden dolayı büyük overyan adenomlar nadir görülmektedir.Müsinöz kistadenomlar, overi en çok büyüten tümörlerdir

10.4274/tjod.93206 article TR Journal of Turkish Society of Obstetric and Gynecology 2016-03-20
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