- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Diet and metabolism studies
- Blood Pressure and Hypertension Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Mechanical Circulatory Support Devices
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Retinal Imaging and Analysis
- Obstructive Sleep Apnea Research
- Chronic Kidney Disease and Diabetes
- Innovations in Medical Education
- Pharmacology and Obesity Treatment
- Acute Ischemic Stroke Management
- Primary Care and Health Outcomes
- Neuroscience of respiration and sleep
- Acute Myocardial Infarction Research
- Diabetes Treatment and Management
- Healthcare Systems and Practices
- Tuberculosis Research and Epidemiology
- Retinal and Optic Conditions
- Tracheal and airway disorders
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
University of Michigan–Ann Arbor
2019-2021
Wake Forest University
2021
University of Iowa Hospitals and Clinics
2015-2020
University of Iowa
2016-2018
Mayo Clinic in Arizona
2018
Iowa City VA Health Care System
2017
Iowa City VA Medical Center
2017
Johns Hopkins University
2012-2016
Iowa Policy Project
2016
The Wright Center for Graduate Medical Education
2013-2015
Abstract Background Catheter ablation is widely accepted intervention for atrial fibrillation (AF) refractory to antiarrhythmic drugs, but limited data are available regarding contemporary trends in major complications and in‐hospital mortality due the procedure. This study was aimed at exploring temporal of mortality, complications, impact hospital volume on frequency AF ablation–related outcomes. Methods The Nationwide Inpatient Sample database utilized identify patients treated with...
Background There are limited data on the role of temporary mechanical circulatory support ( MCS ) devices for cardiogenic shock before left ventricular assist device LVAD surgery. This study sought to evaluate trends use and outcomes in Methods Results was a retrospective cohort from 2005 2014 using National Inpatient Sample (20% stratified sample US hospitals). identified admissions undergoing surgery with preoperative shock. Admissions other cardiac heart transplant were excluded....
BackgroundA large-scale prevalence survey of blindness and visual impairment (The Andhra Pradesh Eye Diseases Study [APEDS1]) was conducted between 1996-2000 on 10,293 individuals all ages in three rural one urban clusters Pradesh, Southern India. More than a decade later (June 2009-March 2010), APEDS1 participants were traced (termed APEDS2) to determine ocular risk factors for mortality this longitudinal cohort. Methods FindingsMortality hazard ratio (HR) analysis performed those aged >30...
Background Oxidative capacity is decreased in type 2 diabetes. Whether oxidative a cause or consequence of diabetes unknown. Our purpose to evaluate whether lactate, marker capacity, associated with incident Methods and Findings We conducted case-cohort study the Atherosclerosis Risk Communities (ARIC) at year 9 follow-up. evaluated lactate’s association risk factors baseline estimated hazard ratio for by quartiles plasma lactate 544 diabetic cases 533 non-cases. Plasma showed graded...
Reducing readmission after catheter ablation (CA) in atrial fibrillation (AF) is important.
Recent evidence suggests that insufficient oxidative capacity or mitochondrial dysfunction may play a causal role in the development of high blood pressure. However, this hypothesis has not been tested general population. We hypothesized lactate, measure capacity, would be positively associated with incident hypertension even after accounting for traditional risk factors. Plasma lactate was measured 5,554 participants from Atherosclerosis Risk Communities (ARIC) Study no subclinical...
Rhabdomyolysis is often associated with sepsis and gram positive bacterial pathogens are reported to be the most frequent cause of induced rhabdomyolysis. We report pattern infecting causal factors in a South-Indian cohort. DESIGN, SETTING, PARTICIPANTS #ENTITYSTARTX00026;Retrospective cohort study adult patients community acquired complicated by rhabdomyolysis from March 2003--August 2008. was defined as serum creatine kinase >2000 IU/L. The population divided into group-I (sepsis...
Purpose The purpose of this study is to assess the relationship between magnitude weight loss and improvement in percentage A1C (A1C%) among overweight obese patients with type 2 diabetes mellitus (DM) undergoing reduction. Methods Case records enrolled university-based management programs were reviewed. Patients sampled if they had a diagnosis DM at least 1 documented A1C% reduction from their baseline value. Weight treatment was individualized consisted calorie-restricted diet, behavior...
We present a 30-year-old South Indian man who presented with complaints of left sided headache and facial pain for past 3 months, severe 10 days. On physical examination, right side the face appeared normal. Left showed signs hemi atrophy minimal drooping eyelid. All Systems were found to be Routine blood urine investigations results within normal limits. X-ray chest revealed no abnormalities x-ray skull both sides equal. Computerized tomogram brain sub dural hygroma midline shift, evidence...
<i>Background/Aim:</i> Subclinical hypothyroidism (SCH) and end-stage renal disease (ESRD) are independent risk factors for cardiovascular mortality. We aimed to study the prevalence of SCH in ESRD patients assessed its associated factors. <i>Methods:</i> This cross-sectional was conducted at 2 tertiary-care centers Chennai, India, over a 3-year period. The group comprised 137 with on thrice weekly regular maintenance hemodialysis. Free thyroxine...
Background— Sex-specific comparative effectiveness of direct oral anticoagulants among patients with nonvalvular atrial fibrillation is not known. Via this retrospective cohort study, we assessed the sex-specific, (rivaroxaban and dabigatran), compared to each other warfarin fibrillation. Methods Results— Elderly (aged ≥66 years) Medicare beneficiaries enrolled in Part D benefit plan from November 2011 October 2013 newly diagnosed formed study (65 734 [44.8%] men 81 137 [55.2%] women)....
Intentional weight loss, primarily by improving insulin resistance, is known to decrease the need for anti-diabetic medications. In this study, we assess magnitude of loss that resulted in dose reductions or discontinuation medications overweight obese patients with type 2 diabetes (DM) undergoing treatment.Case records 50 DM who successfully decreased dosage discontinued after losing via attendance at two University-based, outpatient management centers were analyzed. Follow-up visits,...
Atrial fibrillation (AF) weekend hospitalizations were reported to have poor outcomes compared weekday hospitalizations. The relatively on the weekends are usually referred as ‘weekend effect’. We aim understand trends and among AF primary purpose of this study is evaluate for using Nationwide Inpatient Sample 2005–2014. Hospitalizations with diagnosis, in-hospital mortality, length stay, co-morbidities cardioversion procedures been identified international classification diseases 9 codes....
Studies have shown that hypertensive retinal changes (HRC) a moderate accuracy in predicting microalbuminuria (MA) elderly patients (age >65 years). This study is an effort to identify similar relationship aged <65 years.Eight hundred and seventy consecutive (males, 460; females, 410) 18-65 years were assessed for their demographic characteristics other laboratory variables. Patients with diabetes mellitus, metabolic syndrome overt nephropathy excluded. Optic fundi HRC after pupillary...
Intentional weight loss, by reducing insulin resistance, results in both better glycemic control and decreased need for anti-diabetic medications. However, not everyone who is successful with loss able to reduce medication use. In this retrospective cohort study, we assessed the predictive accuracy of baseline triglyceride (TGL)/HDL ratio, a marker screen patients success use loss.Case records 121 overweight obese attendees at two outpatient management centers were analyzed. The intervention...