A5100396629- RNA Research and Splicing
- Cancer, Lipids, and Metabolism
- Cancer Genomics and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metabolomics and Mass Spectrometry Studies
- Bone health and treatments
- Lung Cancer Treatments and Mutations
- MicroRNA in disease regulation
- RNA modifications and cancer
- Genomics and Phylogenetic Studies
Zoucheng People's Hospital
2019
Sun Yat-sen University
2010
zMicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs that regulate approximately one-third of human genes at post-transcription level. Previous studies have shown miRNAs were implicated in many cellular processes and participated the progress various tumors including hepatocellular carcinoma (HCC). Among all miRNAs, let-7 family is well recognized to play pivotal roles tumorigenesis by functioning as potential growth suppressor. In present study, we aimed investigate role...
The knowledge of genetic variation in Chinese patients with non–small-cell lung cancer (NSCLC) is still limited. We aimed to profile this 206 NSCLC using next-generation sequencing. Tumor tissues or whole-blood samples were collected and subjected whole-exome targeted sequencing, which included 565 tumor-associated genes, for somatic gene mutation screening copy number (CNV) detection. Potential functions most commonly mutated genes CNV predicted by Gene Ontology (GO) Kyoto Encyclopedia...
Objective: To evaluate the value of serum sialic acid (SA) in diagnosis benign prostatic hyperplasia (BPH), prostate cancer (PCa), and bone metastases PCa patients.Materials Methods: Data from 540 patients who were newly diagnosed with or BPH between November 2014 March 2018 retrospectively collected analyzed.Pretreatment SA levels compared across various groups, then, associations clinic parameters analyzed as well.Univariate multivariate logistic regression analyses further used to...