A5063866821- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Dental Health and Care Utilization
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Musculoskeletal pain and rehabilitation
- Endodontics and Root Canal Treatments
- Salivary Gland Disorders and Functions
- HIV/AIDS oral health manifestations
- Occupational health in dentistry
- Dental Research and COVID-19
- Dental Anxiety and Anesthesia Techniques
- Oral and Maxillofacial Pathology
- Musicians’ Health and Performance
- Gut microbiota and health
- dental development and anomalies
- Spaceflight effects on biology
- Streptococcal Infections and Treatments
- Orthodontics and Dentofacial Orthopedics
- Lipoproteins and Cardiovascular Health
- Bone Metabolism and Diseases
- Orthopaedic implants and arthroplasty
- Dental Education, Practice, Research
The University of Texas Health Science Center at San Antonio
2019-2024
The University of Texas Health Science Center at Houston
2022-2023
New York University
2015-2019
University of California, San Francisco
2004-2018
Peking University
2009
The Ohio State University
2004
University of Toronto
1994-1998
Medical Research Council
1998
Lunenfeld-Tanenbaum Research Institute
1998
Spatial and temporal patterns in microbial communities provide insights into the forces that shape them, their functions roles health disease. Here, we used spatial ecological statistics to analyze role saliva plays structuring bacterial of human mouth using >9000 dental mucosal samples. We show regardless tissue type (teeth, alveolar mucosa, keratinized gingiva, or buccal mucosa), surface-associated vary along an gradient from front back mouth, on exposed tooth surfaces, is pronounced...
Background: Bone loss in periodontitis results from inflammatory reactions that stimulate osteoclastic bone resorption. Bisphosphonates inhibit resorption and increase mass. This study evaluated the effect of bisphosphonate therapy as an adjunct to non‐surgical periodontal treatment patients with moderate severe chronic periodontitis. Methods: Patients were randomized (2:1) one two therapies or placebo for 1 year. All received (scaling, root planing) maintenance every 3 months. Clinical...
Viruses may play an important role in the evolution of human microbial communities. Clustered regularly interspaced short palindromic repeats (CRISPRs) provide bacteria and archaea with adaptive immunity to previously encountered viruses. Little is known about CRISPR composition members communities, relative rate locus change, or how loci differ between microbiota different individuals. We collected saliva from four periodontally healthy subjects over 11- 17-mo time period analyzed sequences...
The Lancet Commission on Education of Health Professionals for the 21 st Century calls enhancing health education needs and challenges 21st century to improve status globally. To complement report, this article makes recommendations including core global competencies in care professionals specific groups public who are relevant oral a context order tackle burden diseases. Experts from various professional backgrounds developed four target groups: Group 1 was defined as dental students,...
Objectives The purpose of this study was to evaluate the COVID-19 vaccination experience among United States-based dental professionals and students: understand their beliefs, concerns, safety confidence levels, side effects experienced after vaccination; striving boost acceptability curtail pandemic. Methods An observational survey approved by University Texas Health San Antonio Institutional Review Board distributed members School Dentistry community using Qualtrics XM software. completed...
Abstract This study resulted in enhanced collagen type 1 and osteocalcin expression human periodontal ligament fibroblasts (hPDLF) when exposed to bioactive glass conditioned media that subsequently may promote early mineralized tissue development. Commercial Bioglass™ (45S5) experimental coating (6P53‐b), were used make a (GCM) for comparison control medium. ICP‐MS analysis showed increased concentrations of Ca 2+ , PO 4 3− Si 4+ Na + 45S5 GCM Mg K 6P53‐b (relative medium). Differentiating...
This study tests the hypothesis that silicon and calcium ions combinatorially target gene expression during osteoblast differentiation. MC3T3-E1 subclone 4 progenitors (transformed mouse calvarial osteoblasts) were exposed to Si4+ (from Na2SiO3) Ca2+ CaCl2:H2O) ion treatments both individually (0.4 mM each + control treatment) 0.4 compared treated (α-minimum essential medium, 10% fetal bovine serum, 1% penicillin-streptomycin) cells. Cell proliferation studies showed no significant increase...
Abstract Objective To investigate the association between severity of periodontitis (exposure) and dyslipidemia (outcome). Methods This was a cross‐sectional study users public health services. Periodontitis defined using Center for Disease Prevention Control American Academy Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis based Guidelines total cardiovascular risk World Health Organization. Weight, height, waist circumference, blood...
Alterations of the host response by tobacco smoke adversely affect periodontium. In this study, we examined effects in vitro acute exposure on changes m‐RNA expression primary peripheral mononuclear blood cells through microarray analysis. Mononuclear were isolated from four healthy non‐smokers and plated culture wells. Half then exposed to 5 min smoke. Fluorescent c‐DNA probes prepared linearly amplified m‐RNAs for each sample hybridized cDNA microarrays representing ∼30,000 human genes....