ABSTRACT The saePQRS system of Staphylococcus aureus controls the expression major virulence factors and encodes a histidine kinase (SaeS), response regulator (SaeR), membrane protein (SaeQ), lipoprotein (SaeP). widely used strain Newman is characterized by single amino acid change in sensory domain SaeS (Pro18 [SaeS P ], compared with Leu18 other strains L ]). determines activation class I sae target genes ( coa , fnbA eap sib efb fib ), which are highly expressed Newman. In contrast, II...

Periprosthetic fractures after total knee arthroplasty (TKA) are an increasing problem and challenging to treat. The tibial side is commonly less affected than the femoral wherefore few studies case reports available. aim of this study was analyze outcome periprosthetic compare our data with current literature. All TKA that were treated at Level 1 Trauma Center between 2011 2015 included analyzed consecutively. Felix classification used assess fracture type evaluation radiological clinical...

In paediatric rosacea, ocular symptoms are often predominant. Literature about systemic therapy of rosacea is sparse, though.Analysis children with treated systemically, particularly addressing remission and recurrence rates.Retrospective study reviewing the medical records antibiotic therapy. Nine 19 patients were chosen for detailed analysis. To our knowledge, this first in requiring a larger patient group longer follow-up (mean = 30.2 months).17 (89.5%) suffered from blepharitis, 15...

Abstract Introduction There is a tremendous scope of hardware and software development going on in augmented reality (AR), also trauma orthopaedic surgery. However, there are only few systems available for intra-operative 3D imaging guidance, most them rely peri- X-ray imaging. Especially complex situations such as pelvic surgery or multifragmentary multilevel fractures, implant tracking have proven to be great advantage the outcome can help reduce exposure, at least surgical team (Ochs et...

Delayed bone healing is an eminent problem in the operative treatment of distal tibia fractures. To address this from a biomechanical perspective, DLS 3.7 (Dynamic Locking Screw mm) as new generation locking screws has been developed. This screw enables surgeon to control rigidity plate osteosynthesis and thereby expand clinical options cases where bridge plating chosen for fracture treatment.The purpose present prospective study was evaluate safety use fractures recommended.In...

The Oswestry-Bristol Classification (OBC) was recently described as an MRI-based classification tool for the femoral trochlear. authors demonstrated better inter- and intraobserver agreement compared to Dejour classification. As OBC could potentially provide a very useful grading system trochlear dysplasia, it aim determine reliability of from perspective non-founder.Two orthopaedic surgeons independently assessed 50 MRI scans dysplasia classified each according OBC. Both observers repeated...

Abstract Background This study presents patient-reported outcome measures after combined matrix-associated autologous chondrocyte implantation and bone grafting in high-stage osteochondral lesions of the talus adolescents. Methods A total 12 adolescent patients (13 ankles) received for a solitary lesion at single centre. The Foot Ankle Outcome Score Ability Measure were defined as (median follow-up 80 months [range 22–107 months]). Pre- postoperative ankle radiographs evaluated according to...

The incidence of periprosthetic fractures associated with total knee arthroplasty (PpFxK) has been reported to be 0.3 - 5.5%. 40% all cases are related revision TKA. most common localisation is the distal femur. Classification performed according Rorabeck (RB). RB I II usually treated locked plating and retrograde intramedullary nailing, whereas III an indication for using a hinged endoprosthesis. PpFxK patella can classified Goldberg proximal tibia grouped as in Felix. Interprosthetic...

Abstract Background The aim of this study is to analyse the re-operation rate after surgical treatment osteochondral lesions talus (OCLTs) in children and adolescents. Methods Between 2009 2019, 27 consecutive patients with a solitary OCLT (10 male, 17 female; mean age 16.9 ± 2.2 years; 8 idiopathic vs. 19 traumatic) received primary operative (arthroscopy + bone marrow stimulation [BMS], n = 8; arthroscopy retrograde drilling, autologous chondrocyte implantation [ACI]/autologous grafting,...

Due to complex pelvic geometry, percutaneous screw placement in the posterior acetabular column can pose a major challenge even for experienced surgeons. The present study examined preformed bone stock of 260 hemipelvises. Retrograde screws were virtually implanted using iPlan® CMF (BrainLAB AG, Feldkirchen, Germany); maximal implant length, diameter and angles between trajectories reference planes anterior plane as well midsagittal assessed gender-specific differences. virtual analysis...

Abstract Background Patient-reported outcome measures (PROMs) are gaining increasing importance in the context of quality management. Different PROMs and scoring tools available to assess shoulder function after proximal humeral fracture (PHFx). In Europe, these include Constant-Murley Score (CS), Neer (NS), Oxford Shoulder (OSS), University California at Los Angeles (UCLA) Disabilities Arm, Hands (DASH). addition, health-related life can be assessed by Short Form 36 (SF-36) EuroQol (EQ-5D)....

<b>Hintergrund:</b> In der Unfallchirurgie besteht ein gravierender Nachwuchsmangel, welcher sich in den letzten Jahren verschärft hat. Die Ursachen hierfür sind vielschichtig. Studien haben gezeigt, dass das Interesse am Fach Chirurgie im Verlauf des Medizinstudiums deutlich abnimmt. Um dem Nachwuchsmangel Klinik entgegenzuwirken, sollte schon Studium Interesse, insbesondere auch durch gute Lehrveranstaltungen, für geweckt werden. Ziel dieser Untersuchung war es, die aktuelle Form...

The aim of the study was to identify influencing factors on complication rate in pediatric supracondylar humerus fractures (PSHF). 22 male and 19 female patients with an extension type PSHF underwent conservative operative treatment at a single trauma department were reviewed retrospectively. complications assessed groups without compared according patient- therapy-related factors. overall 19.5%. Two had primary 4 postoperative neurological deficit. One patient developed pin infection after...

Abstract Background There are no recent studies on the frequency of paediatric lower extremity fractures in Germany. The aims this study were to report fracture rates treated German hospitals 2002 and 2017 detect changes over time as well evaluate gender age distribution for each location. Methods Data from National Hospital Discharge Registry, which covers 99% all hospitals, used study. absolute frequencies incidence at included data. population was subdivided into four groups: 0–4, 5–9,...