A5102759536- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Nerve Injury and Rehabilitation
- Spine and Intervertebral Disc Pathology
- Knee injuries and reconstruction techniques
- Foot and Ankle Surgery
- Elbow and Forearm Trauma Treatment
- Chronic Myeloid Leukemia Treatments
- Bone health and osteoporosis research
- Hip and Femur Fractures
- Lower Extremity Biomechanics and Pathologies
- Chemical Synthesis and Analysis
- Mesenchymal stem cell research
- Electromagnetic Fields and Biological Effects
- Polyamine Metabolism and Applications
- Pelvic and Acetabular Injuries
- Abdominal Trauma and Injuries
- Bone Tissue Engineering Materials
- Medical Practices and Rehabilitation
- Acute Myeloid Leukemia Research
- Mast cells and histamine
- Pregnancy-related medical research
- Tendon Structure and Treatment
University of Tübingen
2007-2024
BG Klinik Tübingen
2016-2024
Center For Reconstructive Urethral Surgery
2021
Kreiskliniken Reutlingen
2019
Gates Foundation
2009
Abstract Recently, we identified a specific extremely low-frequency pulsed electromagnetic field (ELF-PEMF) that supports human osteoblast (hOBs) function in an ERK1/2-dependent manner, suggesting reactive oxygen species (ROS) being key regulators this process. Thus, study aimed at investigating how ELF-PEMF exposure can modulate hOBs via ROS. Our results show single to induced ROS production hOBs, without reducing intracellular glutathione. Repetitive (>3) however reduced ROS-levels,...
For many years electromagnetic fields (EMFs) have been used clinically with various settings as an exogenous stimulation method to promote fracture healing. However, underlying mechanisms of action and EMF parameters responsible for certain effects remain unclear. Our aim was investigate the influence defined EMFs on human osteoblasts' osteoclasts' viability function. Primary osteoblasts osteoclasts were treated 3 times weekly 21 days during their maturation process using Somagen® device...
The Constant score (CS) is one of the most frequently applied tools for assessment shoulder joint. However, evaluation strength not standardized leading to potential bias when comparing different studies.Seventy-six patients with fractures proximal humerus undergoing open reduction and internal fixation (ORIF) were assessed using CS measurements at deltoid muscle insertion wrist in three arm positions. Variation coefficients evaluated each patient position.Forty women (57%) 36 men (43%)...
The current study describes several surgical techniques for the treatment of reverse Hill - Sachs lesion after posterior shoulder dislocation; we also aimed to present long term results followed a minimum five years.This is prospective case series 17 patients who were treated in our clinic between 2008 and 2011. Patients with defect size smaller than 25% articular surface conservatively. An endoprosthesis glenohumeral joint was implanted bigger 40%. All remaining by variety operative...
Implants made of various types material can be used for the internal fixation fractures. Carbon fiber reinforced polyetheretherketone (CFR-PEEK) is a radiolucent that may have advantageous handling properties compared with titanium implants.Seventy-six patients proximal humerus fractures requiring surgery were randomized to receive fixed-angle plate out either or CFR- PEEK. To measure functional outcome, DASH score (Disabilities Arm, Shoulder, and Hand; primary endpoint), Simple Shoulder...
Abstract Background Recent studies investigating fracture development in Germany are not available especially with regard to demographic change. The primary aim of this study was report trends the upper extremity between 2002 and 2017 evaluate changes over time. Methods Evaluating inpatient data from German National Hospital Discharge Registry (International Classification Diseases, ICD-10) 2017. Total count, incidences percentage following localizations were analysed: proximal humerus,...
Abstract Background Pelvic fractures are rare but serious injuries. The influence of a concomitant abdominal trauma on the time point surgery and quality care regarding reduction or clinical course in pelvic injuries has not been investigated yet. Methods We retrospectively analyzed prospective consecutive cohort from multicenter German Registry Trauma Society years 2003–2017. Demographic, clinical, operative parameters were recorded compared for two groups (isolated fracture vs. combined...
Extremely low-frequency pulsed electromagnetic field (ELF-PEMF) therapy is proposed to support bone healing after injuries and surgical procedures, being of special interest for elderly patients. This study aimed at investigating the effect a specific ELF-PEMF, recently identified osteoblast function in vitro, on high tibial osteotomy (HTO). Patients who underwent HTO were randomized ELF-PEMF or placebo treatment, both applied by optically identical external devices 7 min per day 30 days...
Abstract Introduction Posterior shoulder dislocation in association with reverse Hill–Sachs lesion is a rather rare injury. Few studies reporting results after joint-preserving surgery these cases are available. This current study presents the clinical outcomes 10 years postoperatively. Materials and methods In prospective case series, we operatively treated 12 consecutive patients (all males) posterior associated using techniques. Patients received single center between January 2008...
Heterotopic ossification (HO) after elbow trauma can be responsible for significant motion restrictions. The study’s primary aim was to develop a new X-ray-based classification HO of the elbow. This retrospective study analyzed injury radiographs from 138 patients aged 6–85 years (mean 45.9 ± 18) who underwent operative treatment. applied at 6 weeks, 12 and months postoperatively. severity graded 0 4 localization defined as r (radial), p (posterior), u (ulnar) or (anterior) by two observers....
<b>Hintergrund:</b> Die Rate mangelernährter, stationär behandelter Patienten liegt zwischen 16 und 55 %, die Durchführung eines Screenings auf das Vorliegen einer Ernährungsstörung wird von den Fachgesellschaften fächerübergreifend gefordert. Eine allgemeingültige Empfehlung, welche Erhebungsmethode im Bereich der Orthopädie Unfallchirurgie Verwendung finden sollte, steht bislang aus. Im Rahmen vorliegenden Studie werden anhand zweier etablierter Scores 1.) Prävalenz mangelernährter...
Proximal humerus fractures are seen frequently, particularly in older patients. The development of new osteosynthesis materials is being driven by the high complication rates following surgical treatment proximal fractures. Plate osteosyntheses made steel, titanium and, for several years now, carbon fiber-reinforced polyetheretherketone (CFR-PEEK) used most frequently.A prospective, randomized study was conducted order to evaluate whether there differences functional postoperative outcome...
Ankle fractures are frequently occurring injuries. Despite the relatively simple operative technique, patients often suffer from postoperative complications. Little is known about treatment of implant-associated infections ankle. Therefore, this study shows and evaluates a algorithm in long- short-term outcomes compared to infection-free patients.Data over 20 years level 1 trauma center university hospital was retrospectively analyzed including age, gender, comorbidities, smoking status,...
Abstract Background Patient-reported outcome measures (PROMs) are gaining increasing importance in the context of quality management. Different PROMs and scoring tools available to assess shoulder function after proximal humeral fracture (PHFx). In Europe, these include Constant-Murley Score (CS), Neer (NS), Oxford Shoulder (OSS), University California at Los Angeles (UCLA) Disabilities Arm, Hands (DASH). addition, health-related life can be assessed by Short Form 36 (SF-36) EuroQol (EQ-5D)....
Intervertebral disc degeneration and herniation is one of the major causes lower back pain. Depletion extracellular matrix, culminating in nucleus pulposus (NP) extrusion leads to intervertebral destruction. Currently available surgical treatments reduce pain but do not restore mechanical functionality spine. In order preserve features spine, total or replacement thus became a wide interest. However, this arthroplasty era still an immature state, since none existing products have been...
Background: The increasing incidence of diabetes mellitus is also reflected in the patient population a trauma and orthopaedic centre. Diabetics exhibit more comorbidities than non-diabetics. In addition to surgical problems these patients, hospitalisation often accompanied by complications, which can prolong treatment increase costs. aim this retrospective study analyse diabetics compared non-diabetics, as well differences costs, depending on associated age comorbidities. Patients/Material...