A5101923884- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Advanced Drug Delivery Systems
- Extracellular vesicles in disease
- Carbon and Quantum Dots Applications
- Photodynamic Therapy Research Studies
- Photochromic and Fluorescence Chemistry
- Immunotherapy and Immune Responses
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- Lipid Membrane Structure and Behavior
- Dendrimers and Hyperbranched Polymers
- RNA Interference and Gene Delivery
- Luminescence and Fluorescent Materials
- Pancreatic function and diabetes
- Advancements in Transdermal Drug Delivery
- Angiogenesis and VEGF in Cancer
- Hydrogels: synthesis, properties, applications
- Phagocytosis and Immune Regulation
- Glycogen Storage Diseases and Myoclonus
- Cancer, Hypoxia, and Metabolism
- HIV Research and Treatment
- Natural Compounds in Disease Treatment
Shenyang Pharmaceutical University
2014-2024
Mudanjiang Normal University
2023
A biomimetic nanocomposite made of a ginger-derived exosome and an inorganic framework enables high-performance delivery infliximab via the oral route for inflammatory bowel disease therapy.
Particle size and surface properties are crucial for lymphatic drainage (LN), dendritic cell (DC) uptake, DC maturation, antigen cross-presentation induced by nanovaccine injection, which lead to an effective cell-mediated immune response. However, the manner in particle of vaccine carriers such as mesoporous silica nanoparticles (MSNs) affect this response is unknown. We prepared 50, 100, 200 nm MSNs that adsorbed ovalbumin (OVA) while modifying β-glucan enhance immunogenicity. The results...
Reactive oxygen species (ROS) generated from photosensitizers exhibit great potential for repolarizing immunosuppressive tumor-associated macrophages (TAMs) toward the anti-tumor M1 phenotype, representing a promising cancer immunotherapy strategy. Nevertheless, their effectiveness in eliminating solid tumors is generally limited by instability and inadequate TAMs-specific targeting of photosensitizers. Here, novel core-shell integrated nano platform proposed to achieve coordinated strategy...