A5101776337- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Thyroid Cancer Diagnosis and Treatment
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Stroke Rehabilitation and Recovery
- Ophthalmology and Eye Disorders
- Anesthesia and Sedative Agents
- Advanced Neuroimaging Techniques and Applications
- Acupuncture Treatment Research Studies
- Botulinum Toxin and Related Neurological Disorders
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Retinal and Macular Surgery
- Streptococcal Infections and Treatments
- Infectious Encephalopathies and Encephalitis
- Intracerebral and Subarachnoid Hemorrhage Research
- Ocular Diseases and Behçet’s Syndrome
- Bird parasitology and diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Traumatic Brain Injury Research
- Cerebral Venous Sinus Thrombosis
- Orthopedic Surgery and Rehabilitation
- Sepsis Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
Fudan University
2013-2024
Huashan Hospital
2013-2024
Sun Yat-sen University
2024
Renji Hospital
2022-2023
Shanghai Jiao Tong University
2022-2023
Shanghai University of Traditional Chinese Medicine
2023
Guangdong Provincial People's Hospital
2011-2021
First Affiliated Hospital of Kunming Medical University
2021
Kunming Medical University
2021
Children's Hospital of Chongqing Medical University
2018-2020
The rostral ventromedial medulla (RVM) exerts bidirectional descending modulation of pain attributable to the activity electrophysiologically identified pronociceptive ON and antinociceptive OFF neurons. Here, we report that GABAergic neurons specifically express G protein–coupled estrogen receptor (GPER). GPER+ exhibited characteristic ON-like responses upon peripheral nociceptive stimulation. Optogenetic activation facilitated, but their ablation abrogated, pain. Furthermore, GPER caused...
Abstract Studies demonstrated that pneumonia can decrease vitamin A productions and reduction/deficiency may promote asthma development. Our previous study showed neonatal Streptococcus pneumoniae ( S. ) infection promoted Whether induced was associated with levels remains unclear. The aim of this to investigate the effects on expressions, explore supplement after adulthood Non-lethal established by intranasal inoculation (1-week-old) female BALB/c mice D39. were supplemented or without...
Exploring the brain reorganization patterns associated with language recovery would promote treatment of global aphasia. While functional near-infrared spectroscopy (fNIRS) has been widely used in study speech and impairment, its application field aphasia is still limited.We aimed to identify cortical activation patients during naming repetition tasks.We recruited post-stroke from Department Rehabilitation Medicine at Huashan Hospital. These individuals were diagnosed without cognitive...
To assess the value of acupuncture for promoting recovery patients with ischemic stroke and to determine whether outcomes combined physiotherapy are superior those alone.Prospective randomized controlled trial.Department Rehabilitation Medicine, Huashan Hospital, Fudan University, P. R. China.120 inpatients outpatients (84 men 36 women).Acupuncture, physiotherapy, acupuncture.Motor function in limbs was measured Fugl-Meyer assessment (FMA). The modified Barthel index (MBI) used rate...
Objectives: Effective management of adverse events (AEs) following vandetanib treatment is important to maximize clinical benefits. We examined whether more frequent contact with vandetanib-treated patients reduced AEs CTCAE grade 2 or higher. Study Design: In this open-label, multicentre, phase III study, locally advanced metastatic medullary thyroid cancer were randomized a patient outreach programme (outreach) standard AE monitoring schedule (vandetanib control) for 52 weeks. addition...
Postoperative cognitive dysfunction (POCD) is a medically induced, rapidly occurring postoperative disease, which hard to recover and seriously threatens the quality of life, especially for elderly patients, so it important identify risk factors POCD apply early intervention prevent POCD. As we have known, pain can impair cognition, many surgery patients experience different preoperative pain, but still unknown whether these are vulnerable Here found that chronic (7 days, not 1 day acute...
Background and objectivesThis case report investigates the application of intermittent Theta-Burst Stimulation (iTBS) in aphasia rehabilitation following a right hemisphere stroke.Case presentationA 52-year-old Chinese male with Broca's post-stroke was treated iTBS. His progress evaluated using Functional Near-Infrared Spectroscopy (fNIRS) behavioral assessments. Significant language function improvement noted, fNIRS showing increased activation language-related cortical areas altered...
Our previous study showed that neonatal S. pneumoniae infection aggravated airway inflammation and hyperresponsiveness (AHR) in an OVA-induced allergic asthma model. As smooth muscle (ASM) plays a pivotal role AHR development, we aim to investigate the effects of pneumonia on ASM structure development. Non-lethal was established by intranasally infecting 1-week-old BALB/C mice with strain D39. Five weeks after infection, lungs were collected assess levels α-SMA contractile proteins ASM....
Delayed antimicrobial therapy is associated with poor outcomes in sepsis, but the optimal antibiotic administration time remains unclear. We aimed to investigate effects of on and evaluate an empirical window for children Streptococcus pneumoniae sepsis. This retrospective study enrolled S. sepsis who presented Children's Hospital Chongqing Medical University from May 2011 December 2018. Classification regression tree (CART) analysis was used determine time-to-appropriate-therapy (TTAT)...
Purpose: To present a relatively uncommon case with secondary iris cyst in the anterior chamber and its successful management an mass excision surgery. Case report: A 46-year-old Chinese woman presented dark shadow her left eye for 6 months without any other discomfort. She had history of blunt ocular trauma by badminton strike 3 years ago. Slit-lamp examination showed small, nearly circular, sharply demarcated, movable OS, which could change position head tilt. The segment optical coherence...
This paper offers an interactive scenario of Cool Guy's Adventure for children with Attention Deficit Hyperactivity Disorder (ADHD) based on sensory integration (SIT). We present a design framework that allows occupational therapists to arrange and combine game units difficulty levels. ADHD is one the most common neurodevelopmental disorders childhood. Many studies have utilized HCI technology assist treat patients various mental conditions, helping them lead healthier lives. However, there...
Background: Postoperative parathyroid dysfunction is a prevalent complication of thyroid surgery, however, there no consensus on the trend postoperative function and standardized clinical intervention. This study systematically describes dynamic changes hormone (PTH) after surgery proposes corresponding classifications interventions. Methods: was retrospectively performed in 12,664 patients diagnosed with cancer who underwent surgical treatment from 2012 to 2022. LOWESS regression used...
Objective To assess any differences in brain activation during active, passive and imaginary movement of the hands using blood oxygen level-dependent functional magnetic resonance imaging (fMRI), to provide references for cortical reorganization patients with injuries. Methods Twenty healthy, right-handed, adult volunteers were studied. fMRI was performed fist clutching. Whole analysis group applied get voxels, volume activation, peak t-score its coordinates. Results Active both...
Objective To observe the effects and morphological changes of angle treating angle-closure glaucoma complicated with senile cataract phacoemulsification combined goniosynei-hialysis. Methods Eighty-two patients (86 eyes) suffered from acute or chronic varying degrees were selected. The eyesight, intraocular pressure, vision, depth central anterior chamber morphology all eyes compared preoperative postoperative. Results All followed up for 6 months. pressure 86 was obviously...
Objective To evaluate the therapeutic effect of interlaced small incision cataract extraction and intraocular lens implantation with traheculectomy(triple procedure)upon patients glaucoma cataract.Methods Use triple procedure on 86 eyes 76 cataract.Postoperative changes vision,intraocular pressure(IOP)and filtering bleb were observed.Follow up period ranged from 6 to 24 months,averaged 15 months.Results Average preoperative IOP was 25.43±3.43 mmHg.and postoperative one 14.37±3.31 mmHg.The...
Abstract Background Previously, we showed that neonatal pneumonia caused by Streptococcus pneumoniae ( S. ) promoted adulthood ovalbumin (OVA) induced allergic asthma. Many studies have demonstrated vitamin A deficiency the development of Whether asthma was associated with concentrations remains unclear. Methods Female BALB/c neonates were infected strain D39 and subsequently treated A. Vitamin in lung, serum liver monitored on 2, 5, 7, 14, 21, 28 days post infection. Four weeks after...
Event Abstract Back to Aphasia due local infarction of the corpus callosum after thalamus hemorrhage Qing Yang1, Yue Cao1, Ying Chen1, Tingwei Wang1, Zuojun Ruiping Hu1, Junfa Wu1 and Yi Wu1* 1 Huashan Hospital, Fudan University, China is a rare manifestation lesion. Here we present case 58-year-old right-handed male patient, who first suffered hemorrhagic stroke in right thalamus, followed by ischemic about one week later. As patient’s care-giver reported, his stroke, language abilities...
To investigate the value of hand-held retinal optometer and optical coherence tomography (OCT) in predicting postoperative visual acuity patients with age-related cataract idiopathic macular epiretinal membrane.We retrospectively analyzed data undergoing phacoemulsification combined intraocular lens implantation for our hospital from January, 2019 to April, 2020.Preoperative examination detected membrane 45 (52 eyes) opacity grade C2N2P1 according LOCSⅡ classification criteria.Based on...
In this study, glial cell-derived neurotrophic factor GDNF was used as an evaluation index to explore the effect of dexmedetomidine, a commonly clinical anesthetic and sedative, on activation intestinal cells.Rat cells were selected for in vitro experiments, treated with dexmedetomidine at various concentrations 24 h.The expression fibrillary acidic protein (GFAP) determined by immunofluorescence assay.The mRNA levels measured RT-qPCR Western Blot, respectively.Immunofluorescence GFAP...