A5051681041- Probiotics and Fermented Foods
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Microbial Metabolites in Food Biotechnology
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Polar Research and Ecology
- Digestive system and related health
- Microbial Metabolic Engineering and Bioproduction
- Clostridium difficile and Clostridium perfringens research
- Biochemical and Structural Characterization
- Fermentation and Sensory Analysis
- Plant Pathogens and Fungal Diseases
- Antimicrobial Peptides and Activities
- Enterobacteriaceae and Cronobacter Research
- Mycorrhizal Fungi and Plant Interactions
- Enzyme Production and Characterization
- Cryospheric studies and observations
- Animal Nutrition and Physiology
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Lichen and fungal ecology
- Fungal Biology and Applications
- Fungal and yeast genetics research
Institute of Biochemistry and Biophysics, Polish Academy of Sciences
2015-2025
Polish Academy of Sciences
2010-2015
The inflammatory bowel disease (IBD) is associated with gut microbiota dysbiosis; however, studies on methanogens—especially those focused children—are extremely limited. aim of this study was to determine the abundance total methanogenic archaea and their three subgroups: Methanobrevibacter (Mb.) smithii, Methanosphaera (Ms.) stadtmanae, Methanomassiliicoccales, in feces children both active inactive Crohn’s (CD) ulcerative colitis (UC). results a quantitative real-time PCR were...
Mannose phosphotransferase system (Man-PTS) is the main mannose permease in bacteria but it also a known receptor for subclass IIa bacteriocins (pediocin-like group) as well IId lactococcin A (LcnA) and B (LcnB) (LcnA-like group). Subclass exhibit strong activity against Listeria spp. they are not Lactococcus In contrast, LcnA-like act only lactis strains. Garvicin Q (GarQ) bacteriocin with minor similarity to relatively broad antimicrobial spectrum including, among others, To identify GarQ...
Polaromonas is one of the most abundant genera found on glacier surfaces, yet its ecology remains poorly described. Investigations made to date point towards a uniform distribution phylotypes across globe. We compared 43 isolates obtained from surfaces Arctic and Antarctic glaciers address this issue. 16S rRNA gene sequences, intergenic transcribed spacers (ITS) metabolic fingerprinting showed great differences between hemispheres but also neighboring glaciers. Phylogenetic distance...
Methanogenic archaea are a part of the commensal gut microbiota responsible for hydrogen sink and efficient production short-chain fatty acids. Dysbiosis methanogens is suspected to play role in pathogenesis variety diseases, including inflammatory bowel disease (IBD). Unlike bacteria, diversity seems be higher IBD patients compared healthy subjects, whereas prevalence abundance declines IBD, especially ulcerative colitis. To date, studies focusing on pediatric very limited; nevertheless,...
ABSTRACT Lactococcus lactis subsp. BGMN1-5 produces a leaderless class II bacteriocin called LsbB. To identify the receptor for LsbB, cosmid library of LsbB-sensitive strain BGMN1-596 was constructed. About 150 clones were individually isolated and transferred to LsbB-resistant mutants BGMN1-596. Cosmid pAZILcos/MN2, carrying 40-kb insert, found restore LsbB sensitivity in mutants. Further subcloning revealed that 1.9-kb fragment, containing only one open reading frame, sufficient...
Enterocin K1 (EntK1), enterocin EJ97 (EntEJ97) and LsbB are three sequence related leaderless bacteriocins. Yet kills only lactococci while EntK1 EntEJ97 target wider spectra with being particularly active against Enterococcus faecium, including nosocomial multidrug resistant isolates. NMR study of showed that it had a structure very similar to - both having an amphiphilic N-terminal α-helix unstructured C-terminus. The in is, however, about 3-4 residues longer than LsbB. Enterococcal...
Immunoreactive gluten peptides that are not digested by peptidases produced humans can trigger celiac disease, allergy and non-celiac hypersensitivity. The aim of this study was to evaluate the ability selected probiotic strains hydrolyze immunoreactive gliadin identify peptidase-encoding genes in genomes most efficient strains. Residual immunoreactivity measured after one- or two-step hydrolysis using commercial enzymes bacterial peptidase preparations G12 R5 immunoenzymatic assays....
ABSTRACT The complete genome of Bifidobacterium animalis subsp. lactis BI040—a human stool isolate, was sequenced using Illumina and Oxford Nanopore technologies. BI040 is composed a circular 1,944,141-bp chromosome which carries genes potentially involved in vitamin synthesis gut health.
ABSTRACT We present the complete genome of Lacticaseibacillus rhamnosus strain LR110, a human stool isolate from NORDBIOTIC collection. The consists 2,867,184-bp chromosome with 46.8% GC content. Genomic analysis revealed genes related to thiamine salvage, lactose metabolism, and putrescine biosynthesis, providing insight into strain’s potential probiotic properties.
Surface ice and cryoconite holes of two types polythermal Svalbard Glaciers (Hans Glacier--grounded tidewater glacier Werenskiold Glacier-land-based valley glacier) were investigated in terms chemical composition, microbial abundance diversity. Gathered data served to describe supraglacial habitats compare microbe-environment interactions on those different type glaciers. Hans Glacier samples displayed elevated nutrient levels (DOC, nitrogen seston) compared Glacier. Adjacent tundra...
Abstract Campylobacter jejuni / coli infections are the leading cause of bacterial diarrheal illnesses in humans. Many epidemiological studies indicate that improperly prepared meat from chickens carry a high load their intestinal tracts is key source human infections. LAB , mainly members Lactococcus and Lactobacillus genera, increasingly have been tested as vehicles for delivery heterologous or viral antigens to animal mucosal immune systems. Thus, objective this study was isolate,...
Abstract Most mucoralean fungi are common soil saprotrophs and were probably among the first land colonisers. Although Mucoromycotina representatives grow well on simple sugar media thought to be unable assimilate more complex organic compounds, they often isolated from plant substrates. The main goal of study was explore effects isolation origin phylogenetic placement carbon assimilation capacities a large group saprotrophic (i.e. Umbelopsidales Mucorales). Fifty two strains representing...
Mannose phosphotransferase system (Man-PTS) serves as a receptor for several bacteriocins in sensitive bacterial cells, namely subclass IIa (pediocin-like; pediocins) and IId ones - lactococcin A (LcnA), B (LcnB) garvicin Q (GarQ). Here, to identify the three other narrow-spectrum garvicins A, C (GarA-C) Lactococcus garvieae mutants resistant were generated sequenced look mutations responsible resistance. Spontaneous had their whole genome while obtained by integration of pGhost9::ISS1...
In recent years, glacial surfaces have received much attention as microbial habitats of diverse photoautotrophic and heterotrophic cells. Supraglacial ecosystems are annually covered uncovered by snow. The aim this study is to investigate the community response changing environmental conditions in a transect following receding snow line on surface Ecology Glacier (King George Island, Antarctica). Parameters ice cryoconite holes included chemical composition sediment, Bacteria diversity...
Lactobacillus rhamnosus LOCK900 fulfills the criteria required for probiotic strains. In this study, we report a whole-genome sequence of isolate and compare it with other L. complete genome sequences already published.
Various Lactobacillus paracasei strains are found in diverse environments, including dairy and plant materials the intestinal tract of humans animals, also used food industry or as probiotics. In this study, we have isolated a new strain L. subsp. IBB3423 from samples raw cow milk collected citizen science project. showed some desired probiotic features such high adhesion capacity ability to metabolize inulin. Its complete genome sequence comprising chromosome 3,183,386 bp two plasmids 5986...
Multidrug-resistant Enterococcus faecium strains are currently a leading cause of difficult-to-treat nosocomial infections. The emerging resistance enterococci to last-resort antibiotics, such as daptomycin, prompts search for alternative antimicrobials. Aureocin A53- and enterocin L50-like bacteriocins potent antimicrobial agents that form daptomycin-like cationic complexes have similar cell envelope-targeting mechanism action, suggesting their potential next-generation antibiotics....
Abstract Background Ascomycetous budding yeasts are ubiquitous environmental microorganisms important in food production and medicine. Due to recent intensive genomic research, the taxonomy of yeast is becoming more organized based on identification monophyletic taxa. This includes genera humans, such as Kazachstania . Until now, humilis (previously Candida ) was regarded a sourdough-specific yeast. In addition, any antibacterial activity has not been associated with this species. Results...
We report the complete genome sequence of
We report the genome sequence of human fecal isolate
modulation of gut microbiota by probiotics has been proposed as a target for intervention to reduce bone mineral density (BMD) loss in the postmenopausal period. This study aims evaluate effect