Valéry Legrain

ORCID: 0000-0002-4744-8596
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About
Contact & Profiles
Research Areas
  • Pain Management and Placebo Effect
  • Pain Mechanisms and Treatments
  • Musculoskeletal pain and rehabilitation
  • Neural and Behavioral Psychology Studies
  • Pain Management and Treatment
  • EEG and Brain-Computer Interfaces
  • Spatial Neglect and Hemispheric Dysfunction
  • Virtual Reality Applications and Impacts
  • Visual perception and processing mechanisms
  • Olfactory and Sensory Function Studies
  • Multisensory perception and integration
  • Tactile and Sensory Interactions
  • Neural dynamics and brain function
  • Motor Control and Adaptation
  • Transcranial Magnetic Stimulation Studies
  • Myofascial pain diagnosis and treatment
  • Laser Applications in Dentistry and Medicine
  • Action Observation and Synchronization
  • Psychosomatic Disorders and Their Treatments
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Heart Rate Variability and Autonomic Control
  • Neuroscience and Neural Engineering
  • Migraine and Headache Studies
  • Muscle activation and electromyography studies
  • Stress Responses and Cortisol

UCLouvain
2016-2025

Institute of Information and Communication Technologies
2018

French Community of Belgium
2018

KU Leuven
2018

Ghent University Hospital
2010-2014

Ghent University
2010-2014

Research Foundation - Flanders
2012

Novem (Netherlands)
2010

3E (Belgium)
2009

Hôpital Pierre Wertheimer
2008

Laser evoked potentials (LEPs) are brain responses to activation of skin nociceptors by laser heat stimuli. LEPs consist three components: N1, N2, and P2. Previous reports have suggested that in contrast earlier activities (N1), after 230-250 ms (N2-P2) modulated attention painful However, the experimental paradigms used were not designed specify attentional processes involved these LEP modulations. We investigated effects selective spatial oddball tasks on LEPs. CO(2) stimuli two different...

10.1016/s0304-3959(02)00051-9 article EN Pain 2002-09-01

Pain can involuntarily capture attention and disrupt pain-unrelated cognitive activities. The brain mechanisms of these effects were explored by laser- visual-evoked potentials. Consecutive nociceptive laser stimuli visual delivered in pairs. Subjects instructed to ignore while performing a task on targets. Because involuntary is particularly sensitive novelty, some trials (17%), unexpected different hand area (location-deviant) relative the more frequent standard stimuli. Compared with...

10.1152/jn.00372.2009 article EN Journal of Neurophysiology 2009-08-19

Brief high-power laser pulses applied onto the hairy skin of distal end a limb generate double sensation related to activation Aδ- and C-fibres, referred as first second pain. However, neurophysiological behavioural responses C-fibres can be studied reliably only if concomitant Aδ-fibres is avoided. Here, using novel CO2 stimulator able deliver constant-temperature heat through feedback regulation power by an online measurement temperature at target site, combined with adaptive staircase...

10.1371/journal.pone.0035817 article EN cc-by PLoS ONE 2012-04-25

Although many studies have investigated the effectiveness of distraction as a method pain control, cognitive processes by which attentional re-direction is achieved, remain unclear. In this study role executive functioning abilities (inhibition, task switching and working memory) in investigated. We hypothesized that terms reduction would be larger participants with better abilities. Ninety-one undergraduate students first performed tasks, subsequently participated cold pressor (CPT)....

10.1016/j.ejpain.2011.01.009 article EN European Journal of Pain 2011-03-16

The periodic presentation of a sensory stimulus induces, at certain frequencies stimulation, sustained electroencephalographic response known as steady-state evoked potential (SS-EP). In the somatosensory, visual, and auditory modalities, SS-EPs are considered to constitute an electrophysiological correlate cortical networks resonating frequency stimulation. present study, we describe characterize, for first time, elicited by selective activation skin nociceptors in humans. stimulation...

10.1523/jneurosci.3977-10.2011 article EN cc-by-nc-sa Journal of Neuroscience 2011-04-20

Attention is acknowledged as an important factor in the modulation of pain. A recent model proposed that effective control pain by attention should not only involve disengagement selective away from nociceptive stimuli, but also guarantee maintained on processing pain-unrelated information without being recaptured stimuli. This predicts executive functions are involved preserving goal priorities throughout achievement cognitive activities. In present study, we tested role working memory...

10.1016/j.pain.2010.11.024 article EN Pain 2011-01-15

The recording of olfactory and trigeminal chemosensory event-related potentials (ERPs) has been proposed as an objective non-invasive technique to study the cortical processing odors in humans. Until now, responses have characterized mainly using across-trial averaging time domain. Unfortunately, ERPs, particular, exhibit a relatively low signal-to-noise ratio. Hence, although is increasingly used basic research well clinical practice evaluate people suffering from disorders, its current...

10.1371/journal.pone.0033221 article EN cc-by PLoS ONE 2012-03-09

Complex regional pain syndrome (CRPS) is a chronic condition associating sensory, motor, trophic and autonomic symptoms in one limb. Cognitive difficulties have also been reported, affecting the patients' ability to mentally represent, perceive use their affected However, nature of these deficits still matter debate. Recent studies suggest that cognitive are limited body-related information body perception, while not extending external space. Here we challenge statement, by using temporal...

10.1038/s41598-017-10077-8 article EN cc-by Scientific Reports 2017-08-22

ABSTRACT Background Complex regional pain syndrome (CRPS) is a debilitating condition characterised by significant heterogeneity. Early diagnosis critical, but limited data exists on the condition's early stages. This study aimed to characterise (very) CRPS patients and explore potential subgroups enhance understanding of its mechanisms. Methods A total 113 were recruited, with 89 undergoing physical assessments. Data included demographic information, work‐related factors, history clinical...

10.1002/ejp.4785 article EN European Journal of Pain 2025-01-18

Laser evoked potentials (LEPs) are nociceptive-related brain responses to activation of cutaneous nociceptors by laser radiant heat stimuli. We previously showed that LEP amplitude during the P2 period (approximately 400 ms) was increased rare noxious stimuli, inside and outside focus spatial attention. It postulated this effect reflected a P3a response indexing an involuntary shift In present study, LEPs were recorded in three-stimulus oddball paradigm, commonly used evoke (or novelty-P3)....

10.1016/s0304-3959(02)00451-7 article EN Pain 2003-04-23

We studied behavioural responses and 32-channel brain potentials to nociceptive stimuli during all-night sleep in 12 healthy subjects, using sequences of thermal laser pulses delivered over the dorsum hand. Laser less than 20 dB perception threshold had clear awakening properties, accordance with intrinsic threatening value signals. Even cases where stimulation did not interrupt sleep, it triggered motor 11% trials. Only four subjects reported dreams, on morning questionnaires there was no...

10.1016/j.pain.2007.10.027 article EN Pain 2007-12-06

Because pain often signals the occurrence of potential tissue damage, a nociceptive stimulus has capacity to involuntarily capture attention and take priority over other sensory inputs. Whether distraction by nociception actually occurs may depend upon cognitive characteristics ongoing activities. The present study tested role working memory in controlling attentional nociception.Participants performed visual discrimination matching tasks which targets were shortly preceded tactile...

10.1371/journal.pone.0020926 article EN cc-by PLoS ONE 2011-06-07
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