Guifang Li

ORCID: 0000-0002-4751-5402
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About
Contact & Profiles
Research Areas
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Epigenetics and DNA Methylation
  • Cancer-related molecular mechanisms research
  • Cancer Immunotherapy and Biomarkers
  • Cancer-related gene regulation
  • Plant tissue culture and regeneration
  • Fungal Biology and Applications
  • Circular RNAs in diseases
  • Gut microbiota and health
  • Plant Disease Management Techniques
  • Protein Degradation and Inhibitors
  • Electron Spin Resonance Studies
  • MXene and MAX Phase Materials
  • Cancer Research and Treatments
  • Neonatal Respiratory Health Research
  • Multiple Myeloma Research and Treatments
  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Ferroptosis and cancer prognosis
  • Infant Nutrition and Health
  • Glutathione Transferases and Polymorphisms
  • Pharmacogenetics and Drug Metabolism
  • Forest Insect Ecology and Management
  • Eicosanoids and Hypertension Pharmacology

Weifang People's Hospital
2013-2025

Zhejiang University
2025

Wuxi Fourth People's Hospital
2023-2024

Jiangnan University
2023-2024

Zhejiang Ocean University
2020

Qingdao Agricultural University
2013-2019

First Affiliated Hospital of Henan University of Science and Technology
2019

Guizhou Provincial People's Hospital
2011-2018

Northwest Normal University
2016

Anhui Provincial Hospital
2014

Valsa mali var. (Vmm), the causal agent of apple tree canker disease, produces various toxic compounds, including protocatechuic acid, p-hydroxybenzoic p-hydroxyacetophenone, 3-(p-hydroxyphenyl)propanoic acid and phloroglucinol. Here, we examined relationship between toxin production pathogenicity Vmm strains determined their bioactivities in several assays, for further elucidating pathogenesis mechanisms developing new procedures to control this disease. The toxins were quantified with high...

10.3390/toxins6031139 article EN cc-by Toxins 2014-03-21

Colorectal cancer (CRC), a major global health concern, may be influenced by dietary protein digestibility impacting gut microbiota and metabolites, which is crucial for therapy effectiveness. This study explored the effects of casein diet (CTL) versus free amino acid (FAA)-based on CRC progression, microbiota, metabolites using carcinogen-induced (AOM/DSS) spontaneous genetically induced (ApcMin/+ mice) mouse models. Comprehensive approaches including 16s rRNA gene sequencing,...

10.3390/nu16071040 article EN Nutrients 2024-04-03

To study the induced resistance in apple against Valsa mali var. (Vmm), a Vmm-apple callus interaction system was developed to evaluate of an attenuated Vmm strain LXS081501 further infection by virulent LXS080601. The index up 97.32 for calli inoculated with LXS080601 alone at 15 days after inoculation whereas it only 41.84 pretreated followed inoculation. In addition, maximum levels free proline, soluble sugar, and protein treated plus were 2.14 3.47 times higher than controls 1.42 1.75...

10.1155/2014/201382 article EN cc-by The Scientific World JOURNAL 2014-01-01

Valsa mali is a causal agent of apple and pear trees canker disease, which destructive disease that causes serious economic losses in eastern Asia, especially China. The lack an efficient transformation system for retards its investigation, poses difficulties to control the disease. In this research, pathogen was established first time using A. tumefaciens ‐mediated (ATMT), with optimal conditions as follows: 10 6 /mL conidia suspension, cocultivation temperature 22°C, 72 hours, 200 μ M...

10.1155/2013/968432 article EN cc-by The Scientific World JOURNAL 2013-01-01

To investigate the risk factors for bronchopulmonary dysplasia (BPD) in twin preterm infants with a gestational age of <34 weeks, and to provide basis early identification BPD clinical practice.

10.7499/j.issn.1008-8830.2312005 article EN PubMed 2024-06-15

To identify potential mutation of TRAPPC2 gene in a Chinese family affected with X-linked spondyloepiphyseal dysplasia tarda (X-SEDL), and explore its underlying molecular mechanism.Peripheral blood samples were collected from 32 members the 50 healthy adults to extract genomic DNA. DNA sequences exons 3 6 their exon/intron boundaries amplified PCR amplification. Direct bi-directional sequencing analysis was performed on products. The aligned reference GenBank determine site type.A...

10.3760/cma.j.issn.1003-9406.2015.04.005 article EN PubMed 2015-08-01
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