A5101869751- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
- Connexins and lens biology
- Plant Physiology and Cultivation Studies
- Flowering Plant Growth and Cultivation
- Hearing Loss and Rehabilitation
- Bariatric Surgery and Outcomes
- Palliative Care and End-of-Life Issues
- Ear Surgery and Otitis Media
- Stress Responses and Cortisol
- Plant Pathogens and Fungal Diseases
- Chinese history and philosophy
- Opioid Use Disorder Treatment
- Cancer Immunotherapy and Biomarkers
- Obesity and Health Practices
- Hormonal and reproductive studies
- Gestational Diabetes Research and Management
- Pancreatic and Hepatic Oncology Research
- Body Contouring and Surgery
- Veterinary Pharmacology and Anesthesia
- Patient Dignity and Privacy
- Dermatology and Skin Diseases
- Prenatal Substance Exposure Effects
- Sphingolipid Metabolism and Signaling
- Cancer Genomics and Diagnostics
University of Florida
2017-2024
University of Florida Health
2022-2024
Southern University of Science and Technology
2022-2024
Florida College
2023
Guangzhou Institute of Dermatology
2022
Guangzhou Medical University
2022
University of Macau
2022
Macau University of Science and Technology
2022
Tianjin People's Hospital
2021
Xinxiang Central Hospital
2021
The aim of this study was to report the effect diabetes mellitus on pharmacokinetics verapamil in a route-dependent manner. Diabetes rats induced by streptozotocin. Plasma concentrations and its metabolite, norverapamil, were measured after oral (10 mg/kg) or intravenous (1 administration. portal plasma administration also determined. Norverapamil formation used for assessing CYP3A activity hepatic intestinal microsomes diabetic rats. protein levels CYP3A1 CYP3A2 liver intestine Western...
Sheehan's syndrome is a rare and under-recognized disorder that may be encountered in variety of clinical settings. The diagnosis the condition challenging due to its rarity fact it often overlooked differential diagnoses. In addition, there are no characteristic features or routine laboratory tests immediately inform diagnosis. We report case 50-year-old woman diagnosed with an anxiety-depressive state, who had marked progressive symptoms, which resolved more rapidly following treatment...
Introduction: Genetic tests, including germline and tumor (somatic) testing, can optimize the clinical care outcomes for cancer patients their family members. However, evidence on patients’ use of genetic testing discussions about it with healthcare providers is limited. Methods: Study participants included survivors aged 18 or older, drawn from 2021 Health Information National Trends Survey (HINTS)-Surveillance, Epidemiology, End Results (SEER) linked database, which comprises three US...
Palliative care can improve the quality of life adolescents and young adults (AYA) with cancer. However, little is known about utilization palliative among AYA cancer patients. Identifying factors associated could inform efforts to access patients living cancer.Using data from National Inpatient Sample 2016-2019, a representative sample US hospitalizations, we examined encounters characteristics hospitalizations high inpatient mortality risk. Survey design-adjusted bivariate multivariable...
The purpose of this study was to investigate the prevalence and etiology hearing loss in primary middle school students Hubei province China. During a 2-year period, 504348 were examined by speech audiometry test, 813 deaf detected. Among students, 232 cases diagnosed with congenital deafness 560 had acquired deafness, among which 276 aminoglycoside-antibiotic-induced deafness. severity could be further ascertained 804 other 402 profound, 363 severe, 21 moderate 18 mild cases. age at onset...
Newborn hearing screening has been successfully implemented worldwide to improve the detection of loss. However, delayed-onset loss subsequent newborn remains a concern. This study aimed investigate prevalence in preschool children who previously passed Hubei Province mid-south China.Preschool were screened by transient evoked otoacoustic emission (TEOAE) for Children referred after TEOAE assessed audiologically.Between March 2010 and September 2011, 28 546 (4.86 ± 1.67 years old), had...
The objective of this study was to compare the effect pulsatile gonadorelin pump (PGP) and cyclical gonadotropin (human chorionic [HCG]/human menopausal [HMG]) therapy (CGT) on spermatogenesis in congenital hypogonadotropic hypogonadism (CHH) men. Twenty-eight azoospermic CHH males were included nonrandomized study. Ten received PGP 18 CGT. primary endpoint earliest time occurred during 24 months treatment. Spermatogenesis significant earlier group than CGT (median 6 14 months, respectively,...
Abstract Anti-PD-1 therapy has shown promising outcomes in the treatment of different types cancer. It is fundamental interest to analyze efficacy anti-PD-1 cancer patients infected with hepatitis B virus (HBV) since comorbidity HBV and widely documented. We designed a multicenter retrospective study evaluate on non-liver HBV. found achieved much better HBV+ than their HBV– counterparts. performed single-cell RNA sequencing (scRNA-seq) peripheral blood mononuclear cells (PBMCs) from...
Chondrocyte is considered the only cell type in cartilage. However, heterogeneity of chondrocytes human articular cartilage still not well defined, which hinders our understanding pathogenesis osteoarthritis (OA). Here, we constructed a single-cell transcriptomic atlas healthy and identified nine chondrocyte subsets including homeostatic chondrocytes, proliferate fibrochondrocytes, hypertrophic (HTC). Interestingly, two distinct HTC subpopulations, among HTC-1 specifically expressed genes...
Recent studies demonstrated that freshwater clam (Corbicula fluminea) has lipid-lowering and hepatoprotective activities, but its effect on immune responses not yet been addressed. Here we showed ethanol extracts of C. fluminea (ECF) reduced nitrite oxide, interleukin-1beta, interleukin-6, tumor necrosis factor-alpha in lipopolysaccharide-activated macrophages. Further, ECF was fractionated into n-hexane, ethyl acetate, ethanol, water soluble fractions. Of these, the acetate fraction (EACF)...
Accumulating evidence has presented that microRNA-148a/152 (miR-148a/152) acts as the tumor inhibitor in various cancers. In this article, we aimed to probe inhibition of colon cancer stem cells by miR-148a/152 cluster via regulation CCT6A. and CCT6A expression tissues was detected. The relationship between clinicopathological features patients with analyzed. Colon (CD44+/CD133+) were selected high/low plasmids synthesized intervene CD44+/CD133+ investigate function invasion, migration,...
Background: Public knowledge and awareness of palliative care (PC) is important to its effective use. However, it remains unclear whether the geographic variation in PC exits United States. This study examined national PC. Methods: The sample was obtained from 2018 National Cancer Institute’s Health Information Trends Survey. Basic PC, goal concordant treatment, misconceptions, primary information source were compared across 4 census regions. Multivariable logistic regression used examine...
Abstract: The aim of this study was to investigate the effect Chrysanthemum morifolium Ramat (CM) extract on pharmacokinetics retinol and activities cytochrome P450s (CYP450s) related retinoid metabolism. Rats were treated with CM for 15 d. Plasma concentrations measured following oral administration (45 mg/kg). Basal levels retinoic acid in serum liver also measured. 7‐Ethoxyresorufin‐ O ‐deethylase activity, phenacetin‐ 7‐pentoxyresorufin‐ used assay CYP1A1, CYP1A2, CYP2B1 hepatic...
We evaluated whether Medicaid expansion (ME) was associated with improved 2-year survival and time to treatment initiation (TTI) among patients gastrointestinal (GI) cancer.
Rural dog populations have long been recognized to be inadequately managed in terms of disease control and prevention. In this study we consider management rural Shanghai its implications for rabies the entire metropolitan area Shanghai. The prerequisite improve vaccination coverage depends on a proper enumeration total population. selected one nine administrative districts (Jiading), within which there are 7 towns 2 industrial zones (township-level division) that contain agricultural areas....