A5026509023- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Heart Failure Treatment and Management
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- Vascular anomalies and interventions
- Cardiac electrophysiology and arrhythmias
- Respiratory Support and Mechanisms
- Medical Imaging and Pathology Studies
- Cardiac Structural Anomalies and Repair
- Semiconductor materials and devices
- Cardiovascular and Diving-Related Complications
- Thyroid Disorders and Treatments
- Cardiovascular and exercise physiology
- Voice and Speech Disorders
- Heart Rate Variability and Autonomic Control
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Mechanical Circulatory Support Devices
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Potassium and Related Disorders
- Pericarditis and Cardiac Tamponade
- Restraint-Related Deaths
Imperial College Healthcare NHS Trust
2024
St George's Hospital
2021-2022
St George’s University Hospitals NHS Foundation Trust
2020-2022
Kingston Hospital NHS Trust
2020-2021
St George's, University of London
2021
Kingston Hospital
2021
Royal Brompton Hospital
2015-2017
Imperial College London
2015-2017
Royal Brompton & Harefield NHS Foundation Trust
2015
Hillingdon Hospital
2011
To investigate the abnormalities of coronary venous system in candidates for cardiac resynchronization therapy (CRT) and describe methods circumventing resulting difficulties.From four implanting institutes, data all CRT implants between October 2008 2020 were screened abnormal anatomy, defined as an anatomical variation not conforming to accepted 'normal' anatomy. Patient demographics, procedural detail, subsequent left ventricle (LV) lead pacing indices collected.From a total 3548...
Abstract Background Cardiac resynchronization therapy‐defibrillator (CRT‐D) implantation via the cephalic vein is feasible and safe. Recent evidence has suggested a higher implantable cardioverter‐defibrillator (ICD) lead failure in multi‐lead defibrillator therapy route. We evaluated relationship between CRT‐D ICD failure. Methods Data was collected from three implanting centers October 2008 September 2017. In total 633 patients were included. Patient characteristics with recorded....
To determine the prognostic implications of changes towards hyponatremia at varying time-points in treatment patients undergoing cardiac resynchronisation therapy (CRT). A retrospective series 249 was studied from 2002 to 2013. The population categorized on basis serum sodium profile baseline, 1 month and 6 follow up visits following successful CRT implantation. composite endpoint all-cause mortality heart failure hospitalisation (defined by need for intravenous diuretic therapy) total (67.8...
The authors describe two cases of massive mitral annular calcification, initially picked up on echocardiography and suspected being neoplastic. Subsequent evaluation by CT scanning confirmed the location, aetiology, structure diagnosis. Both demonstrated large masses, with calcification varying density. This is likely explained presence previously reported amorphous caseous material to be present within such mass structures. Such a feature described as degeneration. patients have been...
Central sleep apnoea (CSA) is common in patients with heart failure (HF), a prevalence of 20-45 %. It marker severity HF and independently associated increased morbidity mortality rates HF. Targeting CSA adaptive servoventilation (ASV) was postulated to improve outcomes; however, the results recent SERVE-HF (Treatment Sleep-disordered Breathing by Adaptive Servo-ventilation Heart Failure Patients) trial showed that reduced ejection fraction (HFrEF), ASV, despite successfully treating CSA,...
Abstract Background • The UK National Health Service (NHS) faces an unprecedented backlog of over 400,000 patients awaiting critical cardiac procedures, incurring thousands excess deaths (1). Longer waiting times to transcatheter aortic valve implantation (TAVI) can increase rates unplanned hospitalisation and death (2). Remote patient monitoring (RPM) improve cardiovascular clinical outcomes (3), but its effectiveness in detecting managing TAVI list deterioration is untested. Purpose 1....
A 65-year-old normotensive, non-athletic man presented to the cardiology clinic with exertional dyspnoea and chest discomfort. Echocardiography revealed mild left ventricular hypertrophy good systolic function but regional wall motion abnormalities suggesting ischaemia. Coronary angiography showed significant three-vessel disease. He underwent coronary artery bypass surgery, which was complicated by recurrent pericardial pleural effusions, requiring a window procedure. Over following year he...
Abstract Case report - Introduction The most recognised presentation of SARS-CoV-2 infection thus far has been respiratory, with hypoxia secondary to bilateral pneumonia and severe acute respiratory distress syndrome as a result the host response virus. We describe investigation management case life threatening myocarditis, no symptoms, occurring in young healthcare-worker during early pandemic. description A 37-year-old male presented dizziness, fever, diarrhoea. He had previous medical...
Background: Cardiac resynchronisation therapy-defibrillator (CRT-D) implantation via the cephalic vein is feasible and safe. Recent evidence has suggested a higher implantable cardioverter defibrillator (ICD) lead failure in multi-lead therapy route. We evaluated relationship between CRT-D ICD failure. Methods: Data was collected from three implanting centres October 2008 – September 2017. In total 631 patients were included. Patient characteristics with recorded. Comparison of ‘cephalic’...
Abstract Funding Acknowledgements Type of funding sources: None. Background Cardiac resynchronisation therapy (CRT) is the cornerstone heart failure management. Delivery a left ventricular lead can occur in small proportion patients undermining benefits this treatment. Abnormal coronary venous anatomy contributing factor to failure. Although epicardial placement available, patient cohort requiring CRT subject higher peri-operative morbidity and mortality than general population; transvenous...
Cardiac implantable electronic device (CIED)-related perforation is uncommon but potentially lethal. Management typically includes the use of computed tomography (CT) scanning and often involves cardiac surgery.Patients presenting to a single referral centre with CIED-related between 2013 2019 were identified. Demographics, diagnostic modalities, method lead revision, 30-day complications examined.A total 46 cases identified; median time from implantation diagnosis was 14 days (interquartile...
Abstract Funding Acknowledgements Type of funding sources: None. Background Cardiac perforation is an uncommon but life-threatening complication cardiac implantable electronic device (CIED) implantation. Management strategy commonly relies on diagnostic Computed Tomography (CT) imaging and surgery. Emerging evidence has indicated a diversion from this approach. Transvenous culprit lead revision been shown to be safe efficacious in limited series. We sought evaluate the outcomes transvenous...