A5025977477- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Retinal Diseases and Treatments
- Diet and metabolism studies
- Oral microbiology and periodontitis research
- Aortic Disease and Treatment Approaches
- Retinopathy of Prematurity Studies
- Infective Endocarditis Diagnosis and Management
- Inflammasome and immune disorders
- Metabolomics and Mass Spectrometry Studies
- Adipose Tissue and Metabolism
- Biomarkers in Disease Mechanisms
- Nerve injury and regeneration
Grigore T. Popa University of Medicine and Pharmacy
2022-2025
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2022-2025
Branched-chain amino acids (BCAAs), comprising leucine (Leu), isoleucine (Ile), and valine (Val), are essential nutrients vital for protein synthesis metabolic regulation via specialized signaling networks. Their association with cardiovascular diseases (CVDs) has become a focal point of scientific debate, emerging evidence suggesting both beneficial detrimental roles. This review aims to dissect the multifaceted relationship between BCAAs health, exploring molecular mechanisms clinical...
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play crucial role in extracellular matrix (ECM) remodeling and implicated the pathogenesis various cardiovascular diseases (CVDs). Their dysregulation has been linked to atherosclerosis, myocardial infarction (MI), heart failure (HF), aortic stenosis, contributing vascular inflammation, plaque destabilization, adverse cardiac remodeling. Recent research highlights MMPs’ involvement beyond ECM degradation,...