- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Venous Thromboembolism Diagnosis and Management
- Hip and Femur Fractures
- Blood transfusion and management
- Pelvic and Acetabular Injuries
- Knee injuries and reconstruction techniques
- Inflammatory Biomarkers in Disease Prognosis
- Anesthesia and Pain Management
- Shoulder Injury and Treatment
- Hematological disorders and diagnostics
- Osteoarthritis Treatment and Mechanisms
- Management of metastatic bone disease
- Bone and Joint Diseases
- Elbow and Forearm Trauma Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Vitamin D Research Studies
- Alkaline Phosphatase Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Lower Extremity Biomechanics and Pathologies
- Diabetic Foot Ulcer Assessment and Management
- Heterotopic Ossification and Related Conditions
- Spinal Fractures and Fixation Techniques
University of Missouri
2022-2024
Brigham and Women's Hospital
2018-2023
Columbia Orthopaedic Group
2023
Tufts Medical Center
2023
Harvard University
2019-2022
Beth Israel Deaconess Medical Center
2020
Massachusetts General Hospital
2020
Cliniques Universitaires Saint-Luc
2014-2019
UCLouvain
2015-2019
Hôpital Saint-Luc
2013-2014
Background: Supracondylar humerus fractures (SCHFs) are the most common elbow fracture in pediatric population. In case of displaced fractures, closed reduction and percutaneous Kirschner wire pinning (CRPP) is commonly performed. Infection rates between 0 7%; however, retrospective studies have shown no benefit preoperative antibiotics. There continues to be notable variability antibiotic usage based on surgeon preference local institutional policy. We conducted a double-blinded, randomized...
Background: Septic arthritis (SA) is a musculoskeletal emergency for which prompt diagnosis and treatment are critical. However, traditional diagnostic criteria of synovial fluid (SF) white blood-cell count (WBC) >50,000 cells/mm 3 or >90% polymorphonuclear leukocytes (%PMN) not particularly sensitive specific the SA. Furthermore, prognostic markers lacking. The purposes this study were to assess discriminative ability SF neutrophil-to-lymphocyte ratio (NLR) in SA serum NLR prognosis...
A paucity of data exists on safe platelet and international normalized ratio (INR) thresholds for hip fracture surgery. Recent work has called into question the safety preoperative INRs < 1.5 total knee arthroplasty, optimal are unknown. The purpose this study was to identify risk 30-day postoperative morbidity mortality in patients with thrombocytopenia or elevated undergoing surgery.The National Surgical Quality Improvement Program database queried surgical treatment a native from 2012...
Abstract Background and objectives Large scale data on the treatment of pathologic proximal femur fractures (PPFFs) are lacking. The purpose this study was to evaluate trends in patient demographics, complication rates, relative utilization rates various techniques associated with PPFFs. Methods American College Surgeons‐National Surgical Quality Improvement Program (NSQIP) database queried for PPFFs from 2009 2017. Patient 30‐day complications, were recorded. Trends these variables...
Background: Antiretroviral therapy has improved the life expectancy of HIV patients, leading to an increase in total joint replacement for age-related osteoarthritis. patients are inherently hypercoagulable at baseline. The goal our study was compare incidence venous thromboembolism (VTE) with HIV-negative controls after replacement. Methods: A multicenter, retrospective cohort 110 (85 hips and 25 knees) 240 (180 85 between 2000 2018. Prophylactic anticoagulation used 98%...
Hypophosphatasia is a rare inherited metabolic disease leading to inhibition of bone and teeth mineralization that can be complicated by multiple insufficiency fractures. Treatment currently limited enzyme replacement therapy using bone-targeting recombinant human alkaline phosphatase, or asfotase alfa. Romosozumab monoclonal anti-sclerostin antibody originally indicated for the treatment osteoporosis in postmenopausal women with high-risk fracture. Recently its indication had been expanded...
Blood loss can increase morbidity and the risk of transfusion after total knee arthroplasty (TKA). This study evaluated difference in blood between minimally invasive TKA performed with without intra-articular use a haemostatic matrix (Floseal®).We retrospectively compared matched pairs two groups (76 patients each group): one group received conventional haemostasis (with bovie electrocoagulation), other was treated an (HM) as adjunct to electrocoagulation. The outcomes were haemoglobin (Hb)...
Aspirin is being used for primary and secondary cardiovascular prevention. It has been proposed that aspirin should be discontinued 5 to 7 days before surgery. However, discontinuation might increase the risk of cardiac thrombo-embolic co-morbidity. also increases bleeding during after total knee arthroplasty. This study evaluated if intra-articular use a haemostatic matrix (Floseal®) decrease blood loss in arthroplasty performed under continued use.We retrospectively compared matched pairs...
The sacro-femoro-pubic (SFP) angle is a surrogate measurement for pelvic tilt obtained on anteroposterior (AP) pelvis radiographs. It unknown whether the SFP can be measured reliably by senior surgeons and trainees alike. We conducted an intrareader interreader reliability study using preoperative AP Using our hospital electronic database, we randomly selected 31 subjects undergoing primary total hip arthroplasty. An attending orthopedic surgeon two surgery residents performed separate...