- Innovation and Knowledge Management
- Energy, Environment, Economic Growth
- Intellectual Capital and Performance Analysis
- Botulinum Toxin and Related Neurological Disorders
- Facial Nerve Paralysis Treatment and Research
- University-Industry-Government Innovation Models
- Trigeminal Neuralgia and Treatments
- Aviation Industry Analysis and Trends
- Economic and Technological Innovation
- Neuroinflammation and Neurodegeneration Mechanisms
- Entrepreneurship Studies and Influences
- Vehicle emissions and performance
- Business Strategy and Innovation
- Transportation Planning and Optimization
- Hydrocarbon exploration and reservoir analysis
- Environmental Sustainability in Business
- Multiple Sclerosis Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Energy, Environment, and Transportation Policies
- Job Satisfaction and Organizational Behavior
- Epigenetics and DNA Methylation
- Geochemistry and Elemental Analysis
- Innovation and Socioeconomic Development
- Emergency and Acute Care Studies
- Glycogen Storage Diseases and Myoclonus
Sichuan University
2010-2024
Shanghai Jiao Tong University
2014-2022
Tongren Hospital
2018-2022
Research Institute of Petroleum Exploration and Development
2020
Shanghai Municipal Commission of Health and Family Planning
2018
Renji Hospital
2014-2015
Multiple sclerosis (MS) is an incurable and progressive neurodegenerative disease that affects more than 2.5 million people worldwide brings tremendous economic pressures to society. However, the pathophysiology of MS still not fully elucidated, there no effective treatment. Demyelination thought be primary pathophysiological alteration in MS, our previous study found abnormal lipid metabolism demyelinated corpus callosum. Growing evidence indicates central nervous system (CNS) demyelinating...
Multiple sclerosis (MS) is a neurodegenerative disorder characterized by periodic neuronal demyelination, which leads to range of symptoms and eventually disability. The goal this research was use UPLC-Orbitrap/MS identify validated biomarkers explore the metabolic mechanisms MS in mice. Thirty-two C57BL/6 male mice were randomized into two groups that fed either normal food or 0.2% CPZ for 11 weeks. mouse demyelination model assessed LFB expression MBP immunofluorescence...
To develop and validate an admission warning strategy that incorporates the general emergency department indicators for predicting hospital discharge outcome of patients with traumatic brain injury (TBI) in China.This was developed a primary cohort consisted 605 TBI who were admitted within 6 h injury. The least absolute shrinkage selection operator multivariable logistic regression analysis used to early selected indicators. Two sub-cohorts consisting 180 107 external validation.Indicators...
Background: PYGL has been reported as a glycogen degradation-related gene, which is up-regulated in many tumors. This study was designed to investigate the predictive value of high expression patients with gliomas through bioinformatics analysis gene transcriptome and single-cell sequencing data. Methods: The data 595 glioma from TCGA database RNA 7,930 GBM cells GEO were included study. Differential used find distribution different groups patients. OS assess influence on prognosis...
In the context of knowledge economy, role traditional leadership for enterprises is questioned. Based on contingency theory and resource-based view, this paper proposes important platform leadership, a new type in line with times, sustainable competitive advantage. We conducted an empirical study to examine confirm positive effects advantage ambidextrous learning. also verified mediation effect exploratory exploitative learning Additionally, relevant discussion research contributions are put forward.
Traumatic brain injury (TBI) is a leading cause of disability and mortality worldwide, whose symptoms ranging from mild to severe, even life-threatening. However, specific cell types key regulators involved in traumatic have not been well elucidated. In this study, utilizing single-cell RNA-seq (scRNA-seq) data mice with TBI, we successfully identified characterized 13 populations including astrocytes, oligodendrocyte, newly formed oligodendrocytes, microglia, two endothelial cells, five...
Purpose Global climate change is a serious threat to the survival and development of mankind. Reducing carbon emissions achieving neutrality are keys reducing greenhouse gas promoting sustainable human development. For many countries, taking China as an example, electric power sector main contributor country’s emissions, well key for neutrality. The low-carbon transition great significance long-term economy. Therefore, on one hand, it necessary improve energy supply structure side increase...
Background Microvascular decompression (MVD) has been widely accepted as a definitive therapy for primary trigeminal neuralgia (TN). However, some patients may not experience relief of TN symptoms following surgery. In this study, the findings redo MVD are discussed. Methods Between 2015 and 2017, 205 with underwent surgery in Shanghai Tongren Hospital. Among these patients, 187 had immediate complete symptoms, 8 improved apparently, 10 reported no symptom relief. Of without relief, 6...
Background: Nervus intermedius neuralgia (NIN), known as geniculate (GN), is an uncommon cranial nerve disease caused by offending vessel compressing the nervus (NI). Microvascular decompression (MVD) has now become a valued treatment approach for NIN because it can resolve neurovascular conflict (NVC) at root entry zone of NI. In era continuously optimizing and improving surgical technique MVD, further minimization all possible postoperative complications not only welcome but also...
Abstract This paper investigates the regional innovation symbiosis effect on firm green innovation. Chinese A‐share listed firms from 2012 to 2018 were sample and entropy method was used construct a index. We found that significantly promoted firm‐level innovation, with government environment investment playing an intermediary role. Further tests indicated more pronounced when in cities had industrial parks publicly disclosed environmental information. State‐owned be likely focus higher systems.
On the basis of previous symbiotic analysis and research, scientific technological activities between subjects are included into evaluation index system network, high-tech industry innovation ecosystem model is established. The symbiosis degree was empirically measured using entropy method with data industries in 32 provinces, autonomous regions municipalities China from 2012 to 2018. Results showed that though a significant development overall has been seen, there still differences speed...
Purpose The reasons for new venture team instability gradually have become a vital issue in the entrepreneurship literature. While chief executive officers’ (CEOs) leadership behaviors is regarded as critical element of governance within teams, few studies explored role played by CEOs’ stability. Drawing on transactional-transformational model, this study divides ventures into two categories, namely, transformational and transactional behaviors. Based social exchange theory information...
Spasmodic torticollis (ST) is an idiopathic neurologic disorder affecting the muscles of neck. Surgery a preferred treatment, when conservative treatments or Botulinum neurotoxin injections fail to relieve symptoms. Our objective here report outcome new surgical method for treating ST patients in our department.The procedure consists rhizotomy spinal accessory nerve (SAN) and C1-C2 roots, coagulation distal end SAN (Group A). The results this were compared with group who underwent only...