A5040944684- Frailty in Older Adults
- Systemic Lupus Erythematosus Research
- Nutrition and Health in Aging
- Autoimmune and Inflammatory Disorders Research
- Health Systems, Economic Evaluations, Quality of Life
- Immune Cell Function and Interaction
- Systemic Sclerosis and Related Diseases
- Drug Transport and Resistance Mechanisms
- Liver Disease Diagnosis and Treatment
- Eosinophilic Esophagitis
- Pregnancy and Medication Impact
- Global Health Care Issues
- Optimism, Hope, and Well-being
- Sleep and related disorders
- Dialysis and Renal Disease Management
- Rheumatoid Arthritis Research and Therapies
- Nutritional Studies and Diet
- Animal Nutrition and Physiology
- Scoliosis diagnosis and treatment
- Resilience and Mental Health
- Peroxisome Proliferator-Activated Receptors
- Reproductive System and Pregnancy
- Genetic Associations and Epidemiology
- COVID-19 and Mental Health
Sun Yat-sen University
2025
Sichuan Agricultural University
2025
Anhui Medical University
2022-2024
Currently, the causal association between sleep disorders and rheumatoid arthritis (RA) has been poorly understood. In this two-sample Mendelian randomization (TSMR) study, we tried to explore whether are causally associated with RA. Seven sleep-related traits were chosen from published Genome-Wide Association Study (GWAS): short duration, frequent insomnia, any getting up, morningness (early-to-bed/up habit), snoring, 27, 53, 57, 70, 274, 42 individual single-nucleotide polymorphisms (SNPs)...
Abstract Background and aims The older people bears a severe burden of disease due to frailty depressive symptoms, however, the results association between two in Chinese have been conflicting. Therefore, this study aimed investigate developmental trajectories interactions symptoms middle-aged adults. Methods used four waves data from 2011, 2013, 2015 2018 China Health Retirement Longitudinal Study (CHARLS) database, focused on ≥ 45 years age, analyzed using latent growth models cross-lagged...
A correlation between sleep and systemic lupus erythematosus (SLE) has been observed in a number of prior investigations. However, little is known regarding the potential causative relationship them. In this study, we selected genetic instruments for traits from pooled data published genome-wide association studies (GWAS). Independent variants associated with six sleep-related (chronotype, duration, short long insomnia, daytime sleepiness) were as instrumental variables. two-sample Mendelian...
Abstract Objective Adequate sleep is closely related to people's health. However, with increasing age, the quality of worsens. At same time, among elderly individuals, frailty also a disturbing factor, which makes individuals more vulnerable negative factors. To explore relationship between two, we conducted this study. Methods In paper, independent genetic variations insomnia, duration and daytime sleepiness were selected as IVs, tools used search published genome-wide association studies...
Abstract Background cumulative evidence from cohort studies suggested that there were inconsistent conclusions as to whether was a bidirectional association between depression and frailty. Therefore, this study used two-sample Mendelian randomisation (MR) investigate the causal relationship Methods we performed univariate multivariate MR analyses assess Independent genetic variants associated with frailty selected instrumental variables. Inverse variance weighted (IVW), MR-Egger, median mode...
The evidence on the relationship between social support and quality of life in female systemic lupus erythematosus (SLE) patients is complex. purpose this study was to explore impacts distress disclosure anxiety association among Chinese women with SLE. A cross-sectional conducted, 237 samples were obtained. Measures included demographic characteristics, Lupus Quality Life (LupusQoL), rate scale (SSRS), index (DDI), self-rating (SAS). Descriptive statistics, correlation analysis, moderated...
Self-disclosure may enhance positive illness perceptions, whereas patients with systemic lupus erythematosus (SLE) always facing negative perceptions due to multiple reasons, so elucidation of factors affecting self-disclosure facilitate the development quality life.A total 161 hospitalized SLE were recruited. Scales on demographic and clinical characteristics, self-disclosure, psychosocial status (e.g. Social Support Rating Scale - SSRS) life used collect related information from clients....
Abstract Background and Aims: The elderly population bears a severe burden of disease due to frailty depressive symptoms, however, the results association between two in Chinese have been conflicting. Therefore, this study aimed investigate developmental trajectories interactions symptoms middle-aged population. Methods used three waves data from 2011, 2013, 2015 China Health Retirement Longitudinal Study (CHARLS) database, focused on people ≥ 45 years age, analyzed using latent growth...