A5043780179- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Water Quality and Pollution Assessment
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Blood groups and transfusion
- Computational Drug Discovery Methods
- Plant and fungal interactions
- Congenital Anomalies and Fetal Surgery
- Polyomavirus and related diseases
- Congenital gastrointestinal and neural anomalies
- Silymarin and Mushroom Poisoning
- Sexual Differentiation and Disorders
- Ideological and Political Education
- Ultrasound in Clinical Applications
- Herbal Medicine Research Studies
- Photopolymerization techniques and applications
- Ion Transport and Channel Regulation
- Herpesvirus Infections and Treatments
- Inhalation and Respiratory Drug Delivery
- Probiotics and Fermented Foods
- Molecular Biology Techniques and Applications
- Hepatitis B Virus Studies
Anhui Medical University
2023
Yinchuan First People's Hospital
2018-2022
Chongqing Medical University
2022
Children's Hospital of Chongqing Medical University
2022
Ningxia Medical University
2010-2021
Hohai University
2020
Sun Yat-sen University
2013-2016
The First Affiliated Hospital, Sun Yat-sen University
2013-2016
Guangdong Medical College
2009-2014
82th Hospital of Pla
2013
Abstract Background cumulative evidence from cohort studies suggested that there were inconsistent conclusions as to whether was a bidirectional association between depression and frailty. Therefore, this study used two-sample Mendelian randomisation (MR) investigate the causal relationship Methods we performed univariate multivariate MR analyses assess Independent genetic variants associated with frailty selected instrumental variables. Inverse variance weighted (IVW), MR-Egger, median mode...
The majority of unexplained respiratory distress syndrome (URDS) cases in late preterm and term infants are caused by genetic abnormalities, with the most common these being ABCA3 gene mutation. At present, it is unclear to neonatologists whether URDS patients mutation have similar or more challenging clinical profiles those without any defined abnormalities. Our study aimed answer this question comparing characteristics severe homozygous compound heterozygous mutations, a single mutation,...
Objectives To investigate the risk profile of preterm birth (PTB) in 2018 China. Method A prospective multicentre case–control study was conducted 15 hospitals located seven provinces throughout three geographical areas (the Eastern, South‐Central and North‐Western regions) total 3147 (<37 +0 weeks) term (37 to 41 +6 live‐birth mothers were included. Designed questionnaires used maternal fetal information. We calculated multivariable logistic regression population attributable (PAR)....
Necrotizing enterocolitis (NEC) is a lethal gastrointestinal tract disease that occurs in premature infants. Adenosine receptor A 2B (A R) regulates the inflammation cytokine secretion and immune cell infiltration colonic pathophysiology conditions. In present study, we aim to determine roles of R development NEC. NEC rat model was established treated with agonist-BAY60-6583 or antagonist-PSB1115. Animals control group were free from any interventions. Our results showed inhibition PSB1115...
Several types of congenital lesions can cause complete or incomplete obstruction the intestine. Our purpose is to present 3 neonates with dual intestinal type I atresia, i.e., simultaneous obstructive at 2 locations in which atresia manifested as diaphragm-like tissue. All cases were female infants ranging age from 14 months. The common symptom all was intermittent persistent vomiting. In some vomitus bilious, and other symptoms included abdominal distention delayed meconium passage. Prior...
Objective To explore the diagnostic value of IGF-1 and IL-18 in premature infants with BPD. Methods Through a prospective observational study, serum samples BPD group non-BPD were collected at different targeted time points, concentrations dynamically monitored by ELISA. The Student t -test one-way analysis variance adopted to analyze data, receiver operating characteristic (ROC) curve was used test value. Result A total 90 VLBW admitted NICU between January 2020 2021 finally included....
Objective To review the clinical features of BA (biliary atresia) patients surviving over 20 years after Kasai operation without liver transplantation and summarize their prognostic factors.Methods A total 37 diagnosed surgically treated at our center from March 1989 to 1993 were studied retrospectively.There 22 males 15 females.Their operative ages ＜60 (n =6),61-80 =14),81-100 =14) ＞100 =3) days respectively.All them classified as type Ⅲ BA.Among them,7 4 females survived...
Objective To explore microbic distribution feature of acute rhinitis pafienta' nasal cavity and dependabihty research respiratory infection.Methods 436 pafienta were randomly divided tO infection group(314)and non-infection group(122)depended on whether accompanying infection.Take blenna narium carry out microbiological detection,meanwhile take blood mesasure the content serum IL-4 IFN-γ.Results The staphylococcus aureus taked most proportion(58.6%and 3 1.2%)of bacterial in group group,the...
The safety of water quantity and quality caused by large-scale blackwater in reservoirs with Eucalyptus plantation is currently a point great interest. largely planted southern China, especially Nanning, Guangxi, where more than 90% the drinking source are surrounded Eucalyptus, different degrees often occur many reservoirs. Recent research has demonstrated that reservoir sediments play an important role migration transformation Fe2+, Mn2+, S2-, dissolved organic carbon (DOC) overlying...
To investigate the diagnostic effect of lung ultrasound on neonatal respiratory distress syndrome (NRDS) and to analyze clinical application value pulmonary score.Sixty-five NRDS babies who were diagnosed in our hospital from August 2019 October 2020 selected as observation group, 65 healthy control group. Children two groups underwent examination. The characteristic signs analyzed, detection rate various score compared between groups.The main manifestations children parenchyma, abnormal...
Objective To investigate the infection situation of Norovirus and its genotype among children with acute diarrhea in autumn winter Shenzhen.Methods Fecal specimens were collected from 307 under 5 years age September 2009 to January 2010 Shenzhen.Reverse transcription polymerase chain reaction (RT-PCR) was used detect nucleic acids Norovirus.Amplicons obtained some positive stools purified sequenced.Phylogenetic analysis genotyping performed combined corresponding nucleotide sequence GenBank...
Objective To investigate the application value of 16S rDNA-based detection technique in rapid screening for and confirmation gonococcemia. Methods A 41-year-old male patient was hospitalized recurrent regular fever chills 1 month. Several days before admission, he developed urgent micturition, frequent micturition pain urination, anemia with emaciation appearance, slightly pale-looking skin mucous membranes. No petechia, eruption or superficial lymphadenectasis observed, but routine blood...
Objective To explore the effect of one to multi-stage goal teaching model in pediatric care teaching.Methods Between July 2009 and June 2011,totals 85 nursing students during undergraduate internship received teaching.After teaching,scores their operation,comprehensive operation theory,and practice attitude were assessed by teachers,as well as they evaluated teachers.Results The excellent rate test results was 98.8％ or more,and satisfaction with teachers 98.6％.Conclusions One can be used...
Objective To express the capsid proteins of WU polyomavirus(WUPyV) for research and find antigen diagnostic value. Methods Coding sequences polyomavirus by PCR were cloned in prokaryotic expression vector PGEX-20T. Recombinant plasmids transformed into E. coli BL21(DE3) induced IPTG expression. identified Western blot. Results SDS-PAGE proved that recombinant showed three bands with molecular relative mass 69×103, 63×103 56×103. The recognized anti-GST McAb. antigenicity was tested blot...