A5084733008- Effects and risks of endocrine disrupting chemicals
- Hormonal and reproductive studies
- Sperm and Testicular Function
- Animal testing and alternatives
- Prostate Cancer Treatment and Research
- Toxic Organic Pollutants Impact
- Cancer, Lipids, and Metabolism
- Muscle metabolism and nutrition
- Sexual Differentiation and Disorders
- Fatty Acid Research and Health
- Genetics, Aging, and Longevity in Model Organisms
- Reproductive Biology and Fertility
- Circadian rhythm and melatonin
Universidade Estadual Paulista (Unesp)
2017-2023
Abstract Background In vitro studies evidenced antitumor effects of omega‐3 polyunsaturated fatty acids ([ n −3] PUFAs), but their on prostate cancer (PCa) remain controversial in epidemiological studies. Here we investigated whether an ( −3) PUFA‐enriched diet affects tumor progression transgenic adenocarcinoma the mouse (TRAMP), at early (12 weeks age) and advanced stages (20 age). Methods TRAMP mice were fed with standard rodent (C12, C20) or containing 10% fish oil (T12, T20). A group 8...
The prostate is an accessory reproductive gland that sensitive to the action of exogenous compounds known as endocrine disrupters alter normal hormonal function. Finasteride a widely used chemical acts inhibit conversion testosterone in its most active form, dihydrotestosterone. It intrauterine exposure finasteride causes changes male even at low dosages; however, it not whether these dosages are capable causing female prostate, which present large number mammalian species, including humans....