- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Abdominal vascular conditions and treatments
- Central Venous Catheters and Hemodialysis
- Vascular anomalies and interventions
- Systemic Sclerosis and Related Diseases
- Diabetic Foot Ulcer Assessment and Management
- Esophageal and GI Pathology
- Dermatologic Treatments and Research
- Aortic aneurysm repair treatments
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Corporate Governance and Law
- Liver Disease and Transplantation
- Anesthesia and Pain Management
- Long-Term Effects of COVID-19
- Retinal and Optic Conditions
- Infective Endocarditis Diagnosis and Management
- Entomological Studies and Ecology
- Abdominal Surgery and Complications
- Muscle and Compartmental Disorders
- Stroke Rehabilitation and Recovery
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Institute of International Relations of Moldova
2023-2025
Nicolae Testemițanu State University of Medicine and Pharmacy
2010-2025
Institutul Medicina de Urgenta
2024
Moldova State University
2017
Abstract Background The aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome acute mesenteric ischaemia (AMI). Methods All adult patients with clinical suspicion AMI admitted or transferred 32 participating hospitals from 06.06.2022 05.04.2023 were included. Participants who subsequently shown not have had localized intestinal gangrene due strangulating bowel obstruction only baseline data...
Abstract Background Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence necrosis currently not available but would help choose the optimal method treatment. The study aims identify combinations biomarkers that can reliably AMI distinguish between potentially reversible ischaemia. Methods This prospective multicentre study. Adult patients...
Hemosuccus pancreaticus (HP) is a rare but potentially life-threatening condition, characterized by upper gastrointestinal bleeding from the ampulla of Vater, often originating ruptured pseudoaneurysm peripancreatic arteries. Despite its rarity, HP presents diagnostic and therapeutic challenge due to elusive clinical presentation complex underlying pathophysiology. In this case report, we presented compelling instance HP, diagnosed in 48-year-old man, complicated with severe anemia...
Objective We hypothesized that the severity of foot poikilothermy can be used for better differentiation grades acute limb ischemia. Thus, study aim was evaluation value non-contact thermometry, performed using a low-cost infrared medical thermometer, as an adjunct clinical diagnosis immediately threatened Methods It single-center observational prospective over 3 years. Patients with ischemia lower limbs grade I–IIB Rutherford treated urgent revascularization were included. Grade determined...
Background: There are no clinical or laboratory markers that can diagnose acute mesenteric ischemia (AMI) accurately. This study aimed to find differences in and between arterial occlusive AMI other abdominal diseases where was initially suspected. Methods: a post hoc of an international prospective multicenter data on patients with suspected were collected. Independent factors associated evaluated multivariable logistic regression analysis. Results: The number 231, consisting thrombotic (n...
Summary: Background: We performed a prospective observational study to compare the results of surgery and anticoagulation in patients with superficial vein thrombosis (SVT). Patients methods: A total 190 (195 limbs) varicose veins SVT were included treated by or surgery. followed-up during 6 months. The primary outcome for treatment efficacy was composite rate extension/recurrence; deep (DVT) symptomatic pulmonary embolism (PE). safety wound complications bleedings. Results: Surgery 85...
A case of severe chronic venous insufficiency caused by pulsatile varicose veins in a 46-year-old man with tricuspid regurgitation is presented. Active leg ulcer complicated recurrent bleeding and inefficacy conservative management serve as indications for surgical treatment. This demonstrates the possibility radical correction pathological reflux means saphenofemoral ligation, foam sclerotherapy subfascial endoscopic perforator surgery.
Management of superficial vein thrombosis (SVT) in patients with varicose veins (VV) is not currently standardized. We performed a survey aimed to demonstrate patterns the management SVT Republic Moldova.This was descriptive study whereby members National Surgical Society were asked complete an online questionnaire. In questionnaire, multiple-choice questions supplemented four clinical vignettes real SVT.The questionnaire completed by 102 participants (31.1% response rate). treatment SVT,...
The primary superficial venous aneurysms of the foot are very rare. A 34-year-old female patient developed a dorsal mass during second trimester pregnancy with no history previous trauma, puncture, or infection. One year later, she was referred to surgical department for excision “foot hygroma.” Based on clinical findings, aneurysm suspected and duplex ultrasound confirmed diagnosis medial marginal vein foot. Excision bipolar ligation performed under local anesthesia. postoperative evolution...
Although saphenofemoral junction aneurysms are not so rare, only scarce of the published cases reported thrombosis aneurysmal sac and saphenous trunk.A 65-year-old male with varicose disease, developed acute ascending superficial vein left greater vein, involving 6-cm aneurysm. The patient underwent common femoral thrombectomy, aneurysm removal, excision uneventful postoperative course.Thrombosed giant require emergent surgical intervention aimed at preventing potential progression to deep...
Warfarin anticoagulation of oncologic patients with DVT may paradoxically progress to phlegmasia cerulea dolens and limb gangrene, due cancer-associated disseminated intravascular coagulation. This case report, written in line the SCARE criteria, endorses venous thrombectomy selected attempt salvage. A young woman's warfarin associated acute ileofemoral that developed over cervical cancer radiation therapy induced DVT, was successfully resolved by clot removal. Extracting thrombus at onset,...
Acute ischemia is a critical condition that occurs when there sudden decrease in arterial blood flow to an extremity and threatens its viability. This clinical requires urgent intervention prevent the development of irreversible possible loss limb. Analysis demographic characteristics patients with acute crucial for effective prevention, diagnosis treatment this medical emergency. An individualized approach choice management strategy accordance data comorbidities can improve outcomes....
The study aimed to evaluate the outcomes of treatment acute limb ischemia (ALI) in patients with novel coronavirus infection (COVID-19). group included 62 patients; 67 extremities: upper – 19 (28.3%), lower 48 (71.6%). Distribution cases according ALI grades (Rutherford): I 7 (10.4%), IIA 10 (14.9%), IIB 34 (50.7%), III 16 (23.8%). COVID-19 was confirmed by polymerase chain reaction test; 45 (72.5%) being documented have lung injury. Fifty (80.6%) underwent surgical on 52 limbs. Amputation...
With the alarming increase in number of ablative interventions treatment varicose disease, application saphenous preserving strategies is current light growing evidence importance vein as a graft. We evaluated clinical case series, which included 194 patients (209 lower limbs) with veins, undergoing surgical preservation. The present article reflects clinical-demographic characteristics and results preoperative imaging investigations, together early outcomes respective types surgery.
The study sought to identify the diagnostic significance of thromboelastography in 44 adult patients with acute superficial thrombophlebitis lower limbs, diagnosed by duplex scanning. distribution thrombotic process was described according Verrel-Steckmeier classification, types II and III defined as «near junction thrombosis». research results testify fact that intensification hemostasis varicose vein has a predominantly structural character, due increased density formed clot. Patients...
Background: Patient reported outcomes are valuable components in the assessment of results treatment for peripheral arterial disease (PAD). The aim study was to translate six item Vascular Quality Life Questionnaire (VascuQoL-6) survey into Romanian, and validate psychometric performance questionnaire a representative cohort patients with lower extremity disease.
Abstract Introduction Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence necrosis currently not available but would help choose the optimal method treatment. The study aims identify combinations biomarkers that can reliably AMI distinguish between potentially reversible ischaemia. Methods This prospective multicentre study. Adult patients...
Background: Acute mesenteric venous thrombosis (MVT) is rarely suspected as primary diagnosis in emergency departments and still carries an in-hospital mortality rate of above 20%. Objectives: The aim this study was to find differences clinical laboratory markers between patients with acute MVT a control group but confirmed not having any type ischaemia (AMI). Design: Data retrieved from the AMESI (Acute MESenteric Ischaemia) study. This international, multicenter prospective case-control 32...
Introduction. Open balloon thrombectomy and embolectomy remain the preferred initial option in management of acute lower limb ischemia (ALI), but various endovascular techniques have become accessible are growing popularity. The aim study was to assess our early experience with percutaneous vacuum-assisted thromboaspiration using Penumbra/Indigo® system for non-traumatic ALI. Material methods. group comprised 13 patients ALI who received treatment between September 2022 June 2023; 7 (53.8%)...
Introduction. Evaluation of patient volemia arriving at a medical service today still represents challenge for specialists, especially in those who need surgical and anesthetic intervention. One the most common systemic side effect to anesthesia is hypotension. Spinal Anesthesia-Induced Hypotension (SAIH) because sympathetic blockade frequently cited as complication subarachnoid anesthesia, its severity being influenced by patient’s volemic state. The aim this literature review analyze if...