- CRISPR and Genetic Engineering
- RNA regulation and disease
- RNA and protein synthesis mechanisms
- Social and Educational Sciences
- Social and Cultural Dynamics
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Inflammatory Bowel Disease
- Advanced Biosensing Techniques and Applications
- Contemporary Sociological Theory and Practice
- Sperm and Testicular Function
- Assistive Technology in Communication and Mobility
- Celiac Disease Research and Management
- Molecular Junctions and Nanostructures
- Tactile and Sensory Interactions
- Gastrointestinal motility and disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Critical Theory and Philosophy
- Immune Cell Function and Interaction
- European and International Law Studies
- Fractional Differential Equations Solutions
- Cardiac Imaging and Diagnostics
- RNA Research and Splicing
- Vestibular and auditory disorders
- Cardiac Valve Diseases and Treatments
Karolinska Institutet
2013-2024
Uppsala University
2013-2023
Örebro University
2007-2022
Stockholm University
2015-2020
Swedish Institute
2020
Science for Life Laboratory
2013-2020
Uppsala University Hospital
2015
Växjö Kommun
2008
Abstract Several studies have indicated that colonic microbiota may exhibit important differences between patients with irritable bowel syndrome (IBS) and healthy controls. Less is known about the of small bowel. We used massive parallel sequencing to explore composition mucosa-associated in IBS analysed capsule biopsies from jejunum 35 (26 females) aged 18-(36)-57 years 16 volunteers (11 20-(32)-48 years. Sequences were based on taxonomic classification. The phyla highest total abundance...
The ill-posed analytic continuation problem for Green's functions and self-energies is investigated by revisiting the Pad\'e approximants technique. We propose to remedy well-known problems of performing an average several continuations, obtained varying number fitted input points coefficients independently. suggested approach then applied test cases, including Sm Pr atomic self-energies, Hubbard model a Bethe lattice Haldane nanoribbon, as well two special functions. sensitivity numerical...
Adenosine-to-inosine (A-to-I) RNA editing is a process that contributes to the diversification of proteins has been shown be essential for neurotransmission and other neuronal functions. However, spatiotemporal properties in brain are largely unknown. Here, we applied situ sequencing distinguish between edited unedited transcripts distinct regions mouse at four developmental stages, investigate diversity landscape.We analyzed codon-altering sites using single-cell resolution, combination...
Renewed attention has been directed to the functions of Y chromosome in central nervous system during early human male development, due recent proposed involvement neurodevelopmental diseases. PCDH11Y and NLGN4Y are special interest because they belong gene families involved cell fate determination formation dendrites axon. We used RNA sequencing, immunocytochemistry a padlock probing rolling circle amplification strategy, distinguish expression X homologs situ brain for first time. To...
Advanced ileocecal Crohn's disease (ICD) is characterized by strictures, inflammation in the enteric nervous system (myenteric plexitis), and a high frequency of NOD2 mutations. Recent findings implicate role another CD susceptibility gene, ATG16L1, host response against single-stranded RNA (ssRNA) viruses. However, viruses unknown. We hypothesized that human enterovirus species B (HEV-B), which are ssRNA with dual tropism both for intestinal epithelium system, could play ICD.We used...
Objective To estimate the prevalence of severe dual sensory loss (DSL) among older persons (aged ≥65 years) in Swedish population, to identify diagnoses that cause DSL, and rehabilitation services which participants have been involved.Design A cross-sectional design was applied. Medical records from Audiological, Low Vision, Vision clinics two counties were used.Study sample 1257 adults, aged years with hearing (HL) (≥70 dB HL) included, whereof 101 had decimal visual acuity ≤0.3.Results...
<title>Abstract</title> Introduction: Ankle fracture is the third most common with a seasonal-occurrence variation in Nordic countries. fractures commonly require surgery and anaesthesia. An important quality-indicator of perioperative-care all-cause 30-day mortality. Little known about early mortality after ankle repair Sweden whether there Aim The aim present register-based study was to assess seasonal-variation associated surgical during 10-year period; 2012–2022 adjusted for age...
The significance of inhibition: a contribution to the agency-structure debateA central problem in social theory today is how integrate agency and structure. vital question explain reality by proceeding from both notion people doing things which affect relationships they are embedded (agency) idea context moulding activity (structure). Sociologists as Pierre Bourdieu, Anthony Giddens Jürgen Habermas call attention practices ”missing link” between In accentuating practices, aim their daily...
This article draws attention to unnoticed aspects of Mead’s social pragmatism. I argue that in his pragmatism, put modern scientific terms, there is a tendency transcend the dualism between agency and structure. Modern scientists as Bourdieu, Giddens Habermas all approach this dualism. pragmatism can be interpreted an attempt by stressing reciprocity The shows view best described following way: structures are both enabling constraining relation individual. In descrip- tion taking role other,...