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A5061627164
Research Areas
- PI3K/AKT/mTOR signaling in cancer
- Chronic Lymphocytic Leukemia Research
- Metabolism, Diabetes, and Cancer
Alexandria University
2023
Targeting toll-like receptors (TLRs), via TLR agonists, has been implicated in the regulation of immunometabolism. B-chronic lymphocytic leukemia (B-CLL) represents a suitable model for B-cell derived malignancies with shifted metabolic adaptations. Several signaling pathways have found to be critical reprogramming CLL, including mechanistic target rapamycin- hypoxia inducible factor-1α (mTOR- HIF-1α) pathway, main regulator glycolysis. Here, we investigated effect TLR7/8 agonist...
10.1007/s12288-023-01649-y
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Indian Journal of Hematology and Blood Transfusion
2023-04-07
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