Rosana Manea

ORCID: 0000-0002-4882-512X
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About
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Research Areas
  • Trauma Management and Diagnosis
  • Renal and related cancers
  • Renal cell carcinoma treatment
  • Abdominal Trauma and Injuries
  • Coronary Artery Anomalies
  • Antimicrobial Peptides and Activities
  • Natural Compound Pharmacology Studies
  • Phytochemicals and Antioxidant Activities
  • Vascular anomalies and interventions
  • Phytochemistry and Biological Activities
  • Thyroid and Parathyroid Surgery
  • Cardiac Structural Anomalies and Repair
  • Polysaccharides and Plant Cell Walls
  • Ethnobotanical and Medicinal Plants Studies
  • Natural Antidiabetic Agents Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Breast Lesions and Carcinomas
  • Spinal Cord Injury Research
  • Spine and Intervertebral Disc Pathology
  • Parathyroid Disorders and Treatments
  • Diet, Metabolism, and Disease
  • Sarcoma Diagnosis and Treatment
  • Computational Drug Discovery Methods
  • Genetic and Kidney Cyst Diseases
  • Essential Oils and Antimicrobial Activity

Transylvania University of Brașov
2018-2025

Clinical Emergency Hospital Bucharest
2023-2025

County Hospital
2023

Mechanistic studies suggest that ginseng, as dietary supplement, plays a key role in disease prevention by modulating the immune function of human body. The root Panax ginseng and quinquefolius (Family: Araliaceae) are commonly known ‘ginseng’. Ginseng roots well for their high content saponins, ginsenosides, phenolic compounds, including carbohydrates carotenoids. In recent years, there is growing interest nutraceutical or functional food with increasing market value. Extracts bioactive...

10.1016/j.tifs.2018.11.008 article EN cc-by-nc-nd Trends in Food Science & Technology 2018-11-09

Natural products are gaining clinical significance in modern day health care systems to prevent diseases. Bitter melon, a promoting vegetable, is traditionally used for medical nutrition therapy cure diabetes but reap maximum claims, vigilant control of its substances diet crucial as part curative action effective management. In the present research, first phase focused on detection key bioactive components, i.e., charantin and vicine different parts fruit. second phase, normal hyperglycemic...

10.3390/plants10040730 article EN cc-by Plants 2021-04-08

Gallbladder carcinoma represents the most aggressive biliary tract cancer and sixth common gastrointestinal malignancy. The diagnosis is a challenging clinical task due to its presentation, which often non-specific, mimicking heterogeneous group of diseases, as well benign processes such complicated cholecystitis, xanthogranulomatous adenomyomatosis, porcelain gallbladder or metastasis (most frequently derived from melanoma, renal cell carcinoma). Risk factors include gallstones, carcinogen...

10.3390/diagnostics14050475 article EN cc-by Diagnostics 2024-02-22

Background and aims: His bundle pacing (HBP) is considered the most physiological form of cardiac pacing. Although feasibility studies have included older patients, specific data for HBP in this population are scarce. This study aimed to evaluate gender differences long-term performance elderly patients with atrioventricular (AV) block. Methods: retrospective 73 aged over 65 years successful at least 2 follow-up. The patients' baseline follow-up clinical procedural characteristics were...

10.3390/jcdd12030088 article EN cc-by Journal of Cardiovascular Development and Disease 2025-02-26

Hundreds of the plants have been explored and evaluated for antioxidant anti-amnesic activities, so far. This study was designed to report biomolecules Pimpinella anisum L. said activities. The aqueous extract dried P. seeds fractionated via column chromatography fractions obtained were assessed inhibition acetylcholinesterase (AChE) in vitro analysis. fraction which best inhibited AChE named as active (P.aAF). P.aAF then chemically analyzed GCMS, indicated that oxadiazole compounds present...

10.3390/molecules28052217 article EN cc-by Molecules 2023-02-27

Background:Dryopteris ramosa is used as an old treatment for several diseases. D. ramose fronds are eaten to treat gastrointestinal (GIT) issues and antibiotic. However, there a dearth of literature justifying its traditional use. Aims objectives: the current work biological molecular docking studies support usage elucidate ramosa's multitarget mechanism. Materials methods: Bioactive compounds were docked in silico. Force displacement transducers coupled with power lab data gathering system...

10.1021/acsomega.3c01907 article EN cc-by-nc-nd ACS Omega 2023-07-20

The study aim was to evaluate the ultrasound (US) signs of mammary lesions classified in Breast Imaging-Reporting and Data System (BI-RADS) score category 3, 4, 5, corresponding US BI-RADS. It also followed correlation between changes suggestive for malignancy with histopathological results evaluated proper management those lesions. There were correlations breast cancer (BC) subtypes receptors [estrogen receptor (ER), progesterone (PR), human epidermal growth factor 2 (HER2)], Ki67 index,...

10.47162/rjme.62.1.28 article EN Romanian Journal of Morphology and Embryology 2021-10-10

Clear cell renal carcinoma is the most frequent type of carcinoma, which often diagnosed incidentally in an advanced stage.We present case a 49-year-old man who presented to emergency department with no specific symptoms. After computed tomography (CT) evaluation, suspicion was raised left tumour. The aim this study underline importance rapid diagnosis and further investigation clear severity cancer.Clear has For complete monitoring, use CT necessary.Clear treated partial nephrectomy can...

10.5334/jbsr.2772 article EN cc-by Journal of the Belgian Society of Radiology 2022-01-01

Single coronary artery anomaly represents a particularly rare entity, which may present with variable clinical scenarios, but in most cases remains asymptomatic. It is considered to be one of the pathological states cause sudden death, especially young adults [1]. We hereby report case R-III type single as classified by Lipton et al., only about 15% all anomalies. Coronary CT angiography well invasive coronarography provide accurate details regarding origin, course and termination anomalies,...

10.5334/jbsr.3122 article EN cc-by Journal of the Belgian Society of Radiology 2023-01-01

Renal cysts have become more commonly recognized in asymptomatic patients due to the improvement and frequency of use advanced imaging modalities, such as CT MRI. The purpose following review is illustrate main most important aspects renal cysts, including a checklist top differential diagnoses also, their further management treatment options. Some can significant clinical implications; this why increased awareness these lesions utmost importance avoid diagnostic pitfalls or complications.

10.31926/but.ms.2023.65.16.2.6 article EN Bulletin of the Transilvania University of Brasov Series VI Medical Sciences 2024-01-19

In case of a traumatic event, preservation the injured renal and kidney function represents goal non-operative management (NOM) trauma. The substantial benefits for minor blunt injury have already been clearly described in current literature, but its value major penetrating injuries are still under debate not highlighted. We hereby fully report 64 years old male patient with history thoraco-abdominal trauma, victim aggression caused by object, which resulted grade IV right associated II...

10.31926/but.ms.2024.66.17.1.4 article EN Bulletin of the Transilvania University of Brasov Series VI Medical Sciences 2024-07-09

Coronary-artery-to-pulmonary-artery fistulae represent rare vascular anomalies defined as abnormal communications between the coronary arteries and pulmonary arterial system. Takotsubo Syndrome represents a stress-induced cardiomyopathy by transient regional systolic dysfunction of left ventricle, with minimal elevation cardiac biomarkers, without angiographic evidence obstructive artery disease. We hereby richly illustrate an unusual case female patient Cardiomyopathy...

10.3390/diagnostics13172751 article EN cc-by Diagnostics 2023-08-24

Hypertension is a major risk factor for progression of the atherosclerotic process and developing degenerative cardiovascular diseases in adulthood. The aim this study to evaluate how measurement carotid intima - media thickness prediction essential hypertension children can be used.The group included 81 control 61 children, all aged between 5 17 years 11 months old, admitted Children Hospital Brasov period 2009 � 2014. protocol included: BMI, blood pressure Doppler echography common artery...

10.37358/rc.18.6.6366 article EN Revista de Chimie 2018-07-15

10.31926/but.ms.2019.61.12.1.4 article EN Bulletin of the Transilvania University of Brasov Series VI Medical Sciences 2019-06-15

Pancreatitis is an acute or chronic inflammatory condition caused by the disruption of exocrine pancreatic cells invasion cells. There are two subtypes pancreatitis: interstitial edematous pancreatitis and necrotising pancreatitis. One most common cause alcohol use. Diagnostic criteria usually used where a patient has distinctive signs, elevated amylase lipase levels, specific imaging findings. Treatment supportive, there no particular pharmacotherapy for this disorder [1]. We present case...

10.26502/acmcr.96550309 article EN Archives of Clinical and Medical Case Reports 2020-01-01

Conus medullaris is the terminal end of spinal cord. This study proposes to assess T2-weighted MRI imaging characteristics 500 patients evaluate level conus medullaris. Magnetic resonance (MRI) has had a major impact on showing termination The was most commonly located from T12 L2 vertebral body levels. activity also provides an overview anatomy medullary cone, which includes structure, embryology, blood supply, and nerves, along with its clinical importance.

10.5455/ijsm.conus-medullaris-review article EN cc-by-nc-sa International Journal of Surgery and Medicine 2020-01-01
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