A5085134619- COVID-19 and Mental Health
- Medical Imaging and Pathology Studies
- Systemic Lupus Erythematosus Research
- Schizophrenia research and treatment
- Pharmaceutical studies and practices
- Platelet Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Plant Pathogenic Bacteria Studies
- Ion Channels and Receptors
- Virus-based gene therapy research
- Diverticular Disease and Complications
- Plant-based Medicinal Research
- Plant Toxicity and Pharmacological Properties
- Parkinson's Disease and Spinal Disorders
- Nosocomial Infections in ICU
- Fungal Plant Pathogen Control
- Treatment of Major Depression
- Pathogenesis and Treatment of Hiccups
- Nutrition, Genetics, and Disease
- Cardiac electrophysiology and arrhythmias
- Vaccine Coverage and Hesitancy
- Hibiscus Plant Research Studies
- Diagnosis and Treatment of Venous Diseases
- Energetic Materials and Combustion
- Essential Oils and Antimicrobial Activity
Transylvania University of Brașov
2016-2024
Amita Health St. Mary's Hospital
2016
Ceftaroline, the active form of prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated community-acquired pneumonia (CAP), including Streptococcus pneumoniae and common Gram-negative pathogens. FOCUS 1 randomized, double-blinded, Phase III study that was conducted to evaluate efficacy safety fosamil in treating patients CAP. The primary objective determine non-inferiority [lower limit 95% confidence interval (CI) ≥ −10%]...
Cucumis sativus L., widely cultivated as an edible vegetable. Its seeds are well reputed for cardiovascular preventive properties. However, the mechanisms underlying protection of C. still unidentified. Therefore, this study utilized a metabolomics approach to investigate putative in myocardial infarction (MI) and vitro models vasoconstriction, atrium, invasive blood pressure measurement. Results showed that Cu.EtOH extract vasorelaxant response with potent hypotensive effect normotensive...
L. is globally cultivated as an edible vegetable. Besides its nutritional benefits, it used in traditional medicines against various ailments. The current study was designed to elucidate the multi-target mechanisms of a
Schizophrenia patients are a population at particular risk of poor outcomes in COVID-19 infection. They have multiple comorbidities that been identified as factors for severe COVID-19: diabetes, hypertension, chronic obstructive respiratory disease, and end-stage renal disease.The aim this research was to evaluate the inflammatory response in-hospital mortality schizophrenia compared control group without mental illness.A total 101 consecutive individuals with tested positive admitted same...
Background Sudden cardiac death (SCD) is a sudden unexpected event, from cause, that occurs in less than 1 hour after the symptom onset person without any previous condition would seem fatal or who was seen symptoms 24 hours before being found dead. Objective The aims of study were to describe features SCD Brasov County, Romania (400,000 inhabitants) according local forensic department autopsy files. Methods We retrospectively chart reviewed number 7200 reports between 2001 and 2015 identify...
Hundreds of the plants have been explored and evaluated for antioxidant anti-amnesic activities, so far. This study was designed to report biomolecules Pimpinella anisum L. said activities. The aqueous extract dried P. seeds fractionated via column chromatography fractions obtained were assessed inhibition acetylcholinesterase (AChE) in vitro analysis. fraction which best inhibited AChE named as active (P.aAF). P.aAF then chemically analyzed GCMS, indicated that oxadiazole compounds present...
Abstract The COVID-19 pandemic has highlighted the critical role of medical doctors in vaccine recommendation adherence. This study aimed to explore factors influencing adherence recommendations among Romanian doctors, one year into vaccination campaign. We conducted a cross-sectional voluntary survey, and data from 94 physician respondents were analysed. found that specialty, fear adverse effects, inflexible thinking significant General practitioners have higher adherence, while surgical...
Achyranthes aspera seeds and leaves are believed to reverse antibiotic resistance increase the efficacy of current drugs. contain many secondary metabolites needed for redressal resistance. In present study, seven different antibiotics were used against five strains bacteria such as Methicillin-resistant Staphylococcus aureus, Enterococcus faecalis, Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa. For aureus Cefoxitin, Penicillin, Co-trimoxazole resistant out...
Introduction: Despite recent developments in therapeutic strategies that limit diabetic kidney disease (DKD) progression, with sodium-glucose cotransporter-2 inhibitors (SGLT2i) added to an optimized renin-angiotensin system (RAS) blockade, there is still a residual cardiorenal morbidity and mortality risk. Objectives: In addition reviewing the clinical evidence current guidelines for management of DKD, we aim address novel strategies, ongoing trials. Materials methods: We searched...
The study aimed to test the inflammation hypothesis in antiphospholipid syndrome (APS) by assessing biochemical markers of and platelet activation. Forty one patients with APS were compared 40 controls. High-sensitivity C-reactive protein (hs-CRP) (as inflammatory biomarker), P-selectin soluble CD40L (sCD40L) activation markers) measured ELISA at enrolment after 12 months follow-up. Serum hs-CRP, sCD40L levels significantly higher was recurrent or acute thrombosis no thrombotic events....
Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease affecting the junction and causes weakness in skeletal muscles. The acetylcholine receptor usually attacked muscles, but other components of junction, such as muscle-specific tyrosine kinase, may be affected. MG can life-threatening when respiratory muscles are involved. first symptom about 2 out 3 cases damage extrinsic eye condition treatable, so an early recognition needed. Although there have been reports associations...
The use of long-acting injectable antipsychotics (LAIs) is considered to be an important treatment option, especially in early stages schizophrenia. aim this study was evaluate the efficacy, safety and sustained remission schizophrenia patients treated with three available LAIs substances: olanzapine pamoate, risperidone microspheres aripiprazole monohydrate. A retrospective chart review evaluating efficacy compared oral antispychotics during a five years period performed. Of 102 included...
Panicum miliaceum L. is a medicinally effective plant used in indigenous system of medicine for variety ailments. However, there no comprehensive study explaining its effectiveness gastrointestinal tract, respiratory, and cardiovascular This was designed to validate the pharmacological basis folkloric use diarrhea, asthma, hypertension. extract analyzed detect presence bioactive compounds by HPLC. The isolated rabbit jejunum, trachea, aorta were vitro experiments using tissue bath assembly...
Ulcère rectal compliqué d'une hémorragie gastro-intestinale: rappel sur les effets gastro-intestinaux des anti-inflammatoires non-stéroïdiensIntroduction.Les anti-inflammatoire non-stéroïdiens (AINS) sont fréquemment utilisés dans le monde entier en tant qu'antalgiques et antipyrétique.Les secondaires multiples (gastro-intestinaux, cardio-vasculaires, rénaux) bien connus malgré fait d'avoir actuellement choix mesures préventives pour complications digestives supérieures, on connait très peu...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
We present the case of a 33-year-old male patient diagnosed with chronic phase myeloid leukemia in June 2008. According to treatment protocols enforced at that time, started oral imatinib 400 mg/day, reaching major molecular response (MMR) 18- month time. The improved over an undetectable BCR-ABL1 transcript level after 36 -48 months treatment. However, profound did not last, requiring switch second line therapy 75 imatinib. Taking nilotinib mg x2/day, achieved 12 months, and 18 treatment,...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
We present a case of type I negative pressure pulmonary edema in healthy 17-year-old boy who underwent an emergent appendectomy under general anesthesia. The particularity our revolves around the administration meperidine for perioperative shivering, along with other anesthetic risk factors, which may have served as trigger edema.We pathophysiological mechanisms, formulation clinical and paraclinical diagnosis principles intensive care therapy. This was first such experienced practice,...
Approximately 30% of patients are included in treatment-resistant schizophrenia and clozapine remains the only antipsychotic with proved superior efficacy these cases. Currently, although is considered as most effective pharmacological intervention for all national guidelines, its use suboptimal due to doctors� concerns about tolerability inappropriate adherence haematological monitoring required early detection severe neutropenia. Although treatment guidelines recommend starting a dose...
Aspergillus fumigatus has been selected to bioleach the metals ion from brown shale.Process parameters like pH (5.0, 5.5, 5.8, 6.0, and 6.5), substrate concentration (2, 4, 6, 8, 10%), pulp density (1, 5, 10, 15, 20%), temperature (30, 35, 40, 45, 50 o C) agitation (100, 150, 200, 250, 300 rpm) were optimized according L25 Taguchi orthogonal experimental array design that resulted in twenty five batch bio recovery experiments.After biorecovery experiments, optimum value of pH, substrate,...