Hiroki Nikawa

ORCID: 0000-0002-4883-5723
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Antifungal resistance and susceptibility
  • Oral microbiology and periodontitis research
  • Dental materials and restorations
  • Dental Implant Techniques and Outcomes
  • Probiotics and Fermented Foods
  • Bone Tissue Engineering Materials
  • Dental Health and Care Utilization
  • Salivary Gland Disorders and Functions
  • Endodontics and Root Canal Treatments
  • Orthopaedic implants and arthroplasty
  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Peptidase Inhibition and Analysis
  • Orthodontics and Dentofacial Orthopedics
  • Temporomandibular Joint Disorders
  • Oral and gingival health research
  • Bacterial biofilms and quorum sensing
  • Dental Erosion and Treatment
  • Mesenchymal stem cell research
  • dental development and anomalies
  • Dental Research and COVID-19
  • Dental Radiography and Imaging
  • Pluripotent Stem Cells Research
  • Infant Nutrition and Health
  • Antimicrobial Peptides and Activities

Waseda University
2025

Hiroshima University
2015-2024

Faculty (United Kingdom)
2006

Capital Medical University
1999

Tokyo Medical and Dental University
1999

Universitas Gadjah Mada
1996

Prince Philip Dental Hospital
1993-1995

University of Hong Kong
1993-1995

To understand which growth factors/cytokines can affect migration of mesenchymal stem cells (MSCs) to injured tissues, we compared the effects many (26) on activity rabbit and human MSCs using a microchemotaxis chamber. Among them, platelet-derived factor (PDGF)-BB, PDGF-AB, epidermal (EGF), HB-EGF, transforming (TGF-α), insulin (IGF-I), hepatocyte (HGF), fibroblast (FGF-2), thrombin consistently enhanced at appropriate concentrations. PDGF-BB showed greatest effect migration. Various...

10.1089/scd.2006.0032 article EN Stem Cells and Development 2007-02-01

summary Candidal colonization and subsequent biofilm formation on denture materials are important in the development of pathogenesis, such as stomatitis. Routine use cleansers is one most effective methods plaque control, although incompatibility soft liners cause damage to materials. The present study, Candida albicans surfaces lining materials, immersed for 180 days were studied. Seven commercially available artificially deteriorated by immersion into three days, fungal growth studied...

10.1046/j.1365-2842.2003.01024.x article EN Journal of Oral Rehabilitation 2003-02-14

The purpose of this study was to explore the occlusal force distribution on dental arch in intercuspal position and evaluate relationship between clenching strength distribution. These variables were recorded using Dental Prescale System 16 healthy young adults. number tooth contacts, contact area increased linearly as increased. greatest at molar region followed by premolar anterior teeth region. proportion (occlusal each region/total force) regions On contrary, decreased findings suggest...

10.1046/j.1365-2842.1999.00473.x article EN Journal of Oral Rehabilitation 1999-12-01

A new antimicrobial material, Ag-zeolite (Zeomic), was combined with a commercial tissue conditioner (GC-Soft Liner (GC); 1-5%) and, through monitoring the pH of growth medium, examined for effects on in vitro and/or acid production Candida albicans protein-free and saliva-coated specimens. The effect incorporation this agent physical property lining material also according to ISO penetration test. Comparison studies were carried out using GC, Coe Comfort (CC) or undecylenate GC (1-5%)...

10.1046/j.1365-2842.1997.d01-297.x article EN Journal of Oral Rehabilitation 1997-05-01

summary Soft denture lining materials were immersed into solutions of cleansers for 8 h at room temperature, and distilled water the remainder 24‐h period 37 °C. Surface roughness soft was measured by contact type surface instrument. For colour stability test, in as described above 180 days. Finally, changes each material quantitatively a photometrical instrument to obtain differences between newly processed specimen specimens ( P < 0·01). An autopolymerizing silicone material, Evatouch,...

10.1046/j.1365-2842.2003.01014.x article EN Journal of Oral Rehabilitation 2003-01-17

Human bone marrow-derived mesenchymal stem cells (hMSCs) are potential cellular sources of therapeutic as they have the ability to proliferate and differentiate into a wide array cell types such osteoblasts, chondroblasts adipocytes. hMSCs been used clinically treat patients with graft vs. host disease, osteogenesis imperfect, or alveolar cleft, suggesting that transplantation is comparatively safe cell-based therapy. However, conventional culture medium for contains fetal bovine serum...

10.1387/ijdb.103232sm article EN The International Journal of Developmental Biology 2011-01-01

The adherence and dissociation of Candida albicans, C. tropicalis, Streptococcus mutans S. sanguis to six substrates including hydroxylapatite (HAP) which exhibit various hydrophobicity, was examined by the use a bioluminescent adenosine triphosphate (ATP) assay. Dissolution HAP albicans or determined spectrophotometrically o-cresolphthalein complexone. In sanguis, amount adherent cells correlated with hydrophobicity substrates. contrast, extraordinary high, although fungi also substrates,...

10.1046/j.0933-7407.2003.00888.x article EN Mycoses 2003-11-28

10.1016/s0022-3913(98)70215-x article EN Journal of Prosthetic Dentistry 1998-02-01

Lactoferrin is an antimicrobial protein present in human mucosal secretions as well saliva. As there no information on the relative fungicidal activity of and bovine lactoferrin, oral isolate Candida albicans was studied for its susceptibility to these two proteins. Exposure a concentration 20 micrograms ml-1 either HLF or BLF at 37 degrees C inactivated yeast same degree irrespective incubation time 45, 90 150 min. A similar study, using min, elicited varying anticandidal against 35...

10.1046/j.1365-280x.1999.00198.x article EN Medical Mycology 1999-02-01

The present study was conducted to evaluate the relationship between maximum bite force and craniofacial morphology. Sixty-four Indonesian female dental students aged 19-27 years with normal occlusion served as subjects. Dental Prescale System used measure using a pressure sensitive sheets while morphology measurements were determined from conventional lateral radiograms. antero-posterior right-left position of occlusal load centre (the OLC) measured also. Stepwise multiple regression...

10.1046/j.1365-2842.2003.01163.x article EN Journal of Oral Rehabilitation 2003-10-20

The present study was a molecular analysis of the initial differentiation osteoclast precursor RAW264.7 cells on titanium specimens. cell line cultured specimens which surfaces were finished by wet grinding with 2000-, 1200-, 600-, or 180-grit waterproof abrasive paper. Total RNA extracted from in presence absence Receptor Activator NF-κB Ligand (RANKL), prior to cDNA synthesis for real-time quantitative reverse transcriptase-polymerase chain reaction analysis. Titanium initially enhanced...

10.4012/dmj.26.739 article EN Dental Materials Journal 2007-01-01
Coming Soon ...