A5020236394- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Osteoarthritis Treatment and Mechanisms
- biodegradable polymer synthesis and properties
- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Agricultural and Food Sciences
- Nanoparticles: synthesis and applications
- Mesenchymal stem cell research
- Plant-Derived Bioactive Compounds
- Biomedical and Engineering Education
- Knee injuries and reconstruction techniques
- Phytochemistry Medicinal Plant Applications
- Polymer Foaming and Composites
- Advanced Sensor and Energy Harvesting Materials
- Total Knee Arthroplasty Outcomes
- Nanoplatforms for cancer theranostics
- Conducting polymers and applications
- Quality and Safety in Healthcare
- Advanced Nanomaterials in Catalysis
- Plant tissue culture and regeneration
- Advanced Drug Delivery Systems
- Periodontal Regeneration and Treatments
- Additive Manufacturing and 3D Printing Technologies
Universidade Federal do ABC
2014-2023
Nanomed (Brazil)
2018-2019
Universidade Estadual de Campinas (UNICAMP)
2000-2002
Because of their antibacterial activity, silver nanoparticles (AgNPs) have been explored in biomedical applications. Similarly, nitric oxide (NO) is an important endogenous free radical with antimicrobial effect and toxicity toward cancer cells that plays pivotal roles several processes. In this work, biogenic AgNPs were prepared using green tea extract the principles chemistry, NO donor S-nitrosoglutathione (GSNO) was by nitrosation glutathione. To enhance potentialities GSNO applications,...
Nitric oxide (NO) and silver nanoparticles (AgNPs) are well-known for their antibacterial activity. In this work, S-nitroso-mercaptosuccinic acid (S-nitroso-MSA), a NO donor, green tea synthesized AgNPs were individually or simultaneously incorporated into alginate hydrogel topical applications. The obtained hydrogels characterized the release diffusion of S-nitroso-MSA from investigated. showed concentration dependent toxicity toward Vero cells. potent effect was demonstrated Escherichia...
Electrospinning is a versatile and efficient technique for obtaining polymeric microfibers nanofibers with great potential applications in tissue engineering, biosensors, filtration, wound dressings, controlled drug release enzyme immobilization. Electrospun fibers are obtained by applying an electric field polymer solution resulting non-woven fibrous mats high surface area relative to volume porosity. In this work, the electrospinning of gelatin/poly(vinyl pyrrolidone) (PVP) blends was...
Nitric oxide (NO) is involved in physiological processes, including vasodilatation, wound healing and antibacterial activities. As NO a free radical, designing drugs to generate therapeutic amounts of controlled spatial time manners still challenge. In this study, the donor S-nitrosoglutathione (GSNO) was incorporated into thermoresponsive Pluronic F-127 (PL)-chitosan (CS) hydrogel, with an easy economically feasible methodology. CS polysaccharide known antimicrobial properties. Scanning...
Abstract The combination of conducting polymers and hydrogels in a conductive interpenetrated polymer network (CIPN) is an interesting strategy to mimic muscles create bending actuators. Whereas the ensures electro pulse flux, hydrogel provides structural support similar human tissues. In this work, poly(acrylic acid) (PAA) polypyrrole (PPy) CIPNs were synthesized aqueous solution three different compositions characterized terms their morphology, composition, mechanical, electrochemical...
Tissue engineering for spinal cord injury (SCI) remains a complex and challenging task. Biomaterial scaffolds have been suggested as potential solution supporting cell survival differentiation at the site. However, different biomaterials display multiple properties that significantly impact neural tissue cellular level. Here, we evaluated behavior of lines seeded on chitosan (CHI), poly (ε-caprolactone) (PCL), (L-lactic acid) (PLLA) scaffolds. We demonstrated surface material play crucial...
Chitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as unique (PL407) or binary (PL407-PL403) systems. Nanoparticles presented diameter of ∼250 nm and zeta potential ∼35 mV with drug loading encapsulation efficiency 98.4 ± 0.3% 36.9 0.12%, respectively. NPX-CS-TPP shifted the sol-gel transition micellization temperatures. PL407-PL403 systems G′ > G″ compared to PL407. SAXS patterns revealed transitions from lamellar hexagonal phase...
Resumo A Engenharia de Tecidos envolve o desenvolvimento novos materiais ou dispositivos capazes interações específicas com os tecidos biológicos, buscando a utilização biocompatíveis que devem servir como arcabouço para crescimento células in vitro, organizando e desenvolvendo tecido posteriormente será implantado no paciente. Uma variedade arcabouços hidrogéis poliméricos, sintéticos naturais, têm sido investigados expansão condrócitos visando reparo da cartilagem lesionada. Um hidrogel...
Nitric oxide (NO) is involved in physiological processes, including vasodilatation, wound healing and antibacterial activities. As NO a free radical, designing drugs to generate therapeutic amounts of controlled spatial time manners still challenge. In this study, the donor S-nitrosoglutathione (GSNO) was incorporated into thermoresponsive Pluronic F-127 (PL) - chitosan (CS) hydrogel, with an easy economically feasible methodology. CS polysaccharide known antimicrobial properties. Scanning...