A5115603059- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Electrospun Nanofibers in Biomedical Applications
- Lubricants and Their Additives
- Hernia repair and management
- Surgical Sutures and Adhesives
- Intestinal and Peritoneal Adhesions
- Polymer Surface Interaction Studies
- Hemostasis and retained surgical items
- Protein Structure and Dynamics
- Cancer Mechanisms and Therapy
- Circular RNAs in diseases
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Graphene and Nanomaterials Applications
- Tribology and Wear Analysis
- biodegradable polymer synthesis and properties
- Orthopaedic implants and arthroplasty
- Force Microscopy Techniques and Applications
- Spectroscopy and Quantum Chemical Studies
- Adhesion, Friction, and Surface Interactions
- Corneal surgery and disorders
- Macrophage Migration Inhibitory Factor
Affiliated Hospital of Hebei University
2023-2025
Institute of Physics
2021
Chinese Academy of Sciences
2021
Abstract The anticoagulation and hemostatic properties of blood-contacting materials are opposite lines research, but their realization mechanisms inspired by each other. Contact between blood implantable biomaterials is a classic problem in tribological as both antithrombotic closely associated with this problem. Thrombus formation on the surfaces biomedical devices can detrimentally affect performance patient life, so specific surface functionalization required. Currently, intensive...
Abstract After abdominopelvic surgery, there are 90–93% of patients who develop postoperative adhesions. Post‐operative adhesions can occur after various surgical procedures, which not only cause a series complications but also increase the economic burden patients. Based on US FDA rules, anti‐adhesive products need to be deeply evaluated for their bio‐functionality in animal models before clinic entrance. However, date, few literatures systematically summarizing establish approaches and...
After cardiac surgery, tissue damage to the heart may cause adhesion between and its surrounding tissues. Post-operative lead limited normal function, decreased quality of increased risk major bleeding during reoperation. Therefore, it is necessary develop an effective anti-adhesion therapy overcome adhesion. An injectable polyzwitterionic lubricant developed prevent tissues maintain pumping function heart. This evaluated in a rat model. Poly (2-methacryloyloxyethyl phosphorylcholine) (i.e.,...
Friction is the trigger cause for excessive exogenous adhesion, leading to poor self-repair of tendon. To address this problem, we developed electrospun dual-functional nanofibers with surface robust superlubricated performance and bioactive agent delivery regulate healing balance by reducing adhesion promoting endogenous healing. Coaxial electrospinning our previous in situ nanocoating growth techniques were employed create lubricative/repairable core–shell structured nanofibrous membrane...
Background: Postoperative abdominal adhesion is a prevalent complication following surgery, with the incidence of reaching up to 90%, which may precipitate range adverse outcomes. Although fibrous membranes loaded various anti-inflammatory or other drugs have been proposed for anti-adhesion, most them suffer from drug-induced effects. Methods: In this study, lecithin-based electrospun polylactic acid (PLA) nanofibrous membrane (L/P-NM) was developed prevention postoperative adhesion,...
Objective To investigate the relationship between astrocyte elevated gene-1 (AEG-1) and microRNA-885-5p, observe influence of microRNA-885-5p on MHCC-97H migration invasion, identify target gene uncover mechanisms AEG-1 promoting cancer metastasis. Methods The experimental study was adopted. The over-expressed plasmid constructed siRNA silent synthesized were transiently transfected into cells, respectively. For trans-fection, cells tranfected with empty Vector NC divided group A as...
Abstract Thermodynamics and structural transitions on protein surfaces remain relatively understudied poorly understood. Wrapping of DNA proteins provides a paradigm for studying surfaces. We used magnetic tweezers to investigate prototypical DNA-interacting protein, i.e., the single-stranded binding (SSB). SSB binds with distinct modes mechanism which is still elusive. The measured thermodynamic parameters relevant SSB-DNA complex are salt-dependent discontinuous at bind-mode transitions....