Xiao Wang

ORCID: 0000-0002-4967-3690
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About
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Research Areas
  • Metal complexes synthesis and properties
  • Metal-Organic Frameworks: Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Radiopharmaceutical Chemistry and Applications
  • Medical Imaging Techniques and Applications
  • Crystal structures of chemical compounds
  • Magnetism in coordination complexes
  • RNA Interference and Gene Delivery
  • Peptidase Inhibition and Analysis
  • Multicomponent Synthesis of Heterocycles
  • Synthesis and Characterization of Heterocyclic Compounds
  • Synthesis and biological activity
  • Bacteriophages and microbial interactions
  • Inorganic and Organometallic Chemistry
  • Lanthanide and Transition Metal Complexes
  • DNA and Nucleic Acid Chemistry
  • Conducting polymers and applications
  • Sulfur-Based Synthesis Techniques
  • Chemical Synthesis and Reactions
  • Acoustic Wave Resonator Technologies
  • Molecular Junctions and Nanostructures
  • Synthetic Organic Chemistry Methods
  • Supramolecular Self-Assembly in Materials
  • Chemical Synthesis and Analysis
  • Optical Systems and Laser Technology

Army Medical University
2025

The First People's Hospital of Shunde
2025

Southern Medical University
2025

Shanghai Ninth People's Hospital
2023-2024

Shanghai Jiao Tong University
2023-2024

Shanghai Normal University
2023-2024

Beijing Institute of Aeronautical Materials
2024

Soochow University
2013-2024

Xiangya Hospital Central South University
2023-2024

Central South University
2023-2024

Solvothermal reactions of Zn(NO3)2 with tetrakis(4-pyridyl)cyclobutane (tpcb) and 1,4-naphthalenedicarboxylic acid (1,4-H2ndc) 2,3-naphthalenedicarboxylic (2,3-H2ndc) in different solvents led to the formation three polydimensional coordination polymers {[Zn2(H2O)(1,4-ndc)2(tpcb)]}n (1), {[Zn(1,4-ndc)(tpcb)0.5]}n (2), {[Zn2(H2O)(2,3-ndc)2(tpcb)]}n (3). Compounds 1–3 were characterized by elemental analysis, IR, powder X-ray diffraction (PXRD), single crystal diffraction. Compound 1 is a...

10.1021/cg4014416 article EN Crystal Growth & Design 2013-12-11

Wireframe DNA origami has emerged as a powerful approach to fabricating nearly arbitrary 2D and 3D geometries at the nanometer-scale. Complex scaffold staple routing needed design wireframe objects, however, render fully automated, geometry-based sequence approaches essential for their synthesis. And structural fidelity can be limited by edges that are composed only of one or two duplexes. Here we introduce automated computational programs assemblies using honeycomb six parallel These show...

10.1038/s41467-019-13457-y article EN cc-by Nature Communications 2019-11-28

Wireframe DNA origami assemblies can now be programmed automatically from the top-down using simple wireframe target geometries, or meshes, in 2D and 3D, either rigid, six-helix bundle (6HB) more compliant, two-helix (DX) edges. While these have numerous applications nanoscale materials fabrication due to their spatial addressability high degree of customization, no easy-to-use graphical user interface software yet exists deploy algorithmic approaches within a single, standalone interface....

10.1093/nar/gkab762 article EN cc-by Nucleic Acids Research 2021-09-08

Caries is one of the most prevalent human diseases, resulting from demineralization tooth hard tissue caused by acids produced bacteria, and can progress to pulpal inflammation. Filling restoration with dental resin composites (DRCs) currently common treatment for caries. However, existing DRCs suffer low fracture strength lack comprehensive anti-caries bioactivity including remineralization, pulp protection, anti-cariogenic bacteria effects. In this study, inspired plant roots' ability...

10.1016/j.bioactmat.2024.02.004 article EN cc-by-nc-nd Bioactive Materials 2024-02-19

Abstract Macrophages are important innate immune defense system cells in the fight against bacterial and fungal pathogenic infections. They exhibit significant plasticity, particularly with their ability to undergo functional differentiation. Additionally, HIF1α is critically involved differentiation of macrophages during inflammation. However, role macrophage protecting different infections remains unclear. In this study, we investigated compared roles effects vitro vivo . We found that...

10.1038/s41598-018-22039-9 article EN cc-by Scientific Reports 2018-02-20

A chiral dimer of an organic semiconductor was assembled from octaniline (octamer polyaniline) conjugated to DNA. Facile reconfiguration between the monomer and octaniline–DNA achieved. The geometry exciton coupling molecules in assembly studied both experimentally theoretically. readily switched different electronic states by protonic doping exhibited a Davydov splitting comparable those previously reported for DNA–dye systems employing dyes with strong transition dipoles. This approach...

10.1021/acsnano.1c09143 article EN cc-by-nc-nd ACS Nano 2022-01-03

Treatment of substituted benzyl alcohols with tosyl chloride resulted in the formation corresponding chlorides, not usual tosylates. A series experiments demonstrated that it was possible to predict whether chlorination or tosylation would occur for and pyridine methanols. electron withdrawing group-substituted gave chlorides moderate yields under mild conditions, which provided a simple way directly prepare from alcohols.

10.3390/molecules16075665 article EN cc-by Molecules 2011-07-01

Fibroblast activation protein (FAP), a type II integral membrane serine protease, is promising target for tumor diagnosis and therapy. OncoFAP has been recently discovered PET imaging procedures various solid malignancies. In this study, we presented the development of manual radiolabeling preparation OncoFAP-based radiopharmaceuticals cancer imaging. A novel series [68Ga/177Lu]Ga/Lu-FAPI-FUSCC-I/II were produced with high radiochemical yields. [68Ga]Ga-FAPI-FUSCC-I/II...

10.1021/acs.molpharmaceut.3c01008 article EN Molecular Pharmaceutics 2024-01-05

Abstract: Iron smelting is one of the primary sources carbon emissions. The development low-carbon ironmaking technologies essential for iron and steel industry to realize “dual carbon” ambition. Hydrogen-based flash technology eliminates traditional pretreatment steps such as sintering, pelletizing, coking while using hydrogen a reducing agent, significantly In present work, computational fluid dynamics approach employed conduct an in-depth analysis radiative properties inside reaction...

10.3390/met15030242 article EN cc-by Metals 2025-02-25

Background Dysthyroid optic neuropathy (DON), the most severe complication of thyroid eye disease (TED), has unclear mechanisms and unsatisfactory treatment outcomes. This study aimed to identify key pathways inflammation-related core genes driving DON progression, potentially informing new therapeutic strategies improving management. Methods Retro-orbital tissues from DON, non-DON TED, healthy controls (HCs) were analyzed using bulk RNA sequencing. Differentially expressed (DEGs) identified...

10.3389/fimmu.2025.1550694 article EN cc-by Frontiers in Immunology 2025-03-12

We describe herein an asymmetric synthesis of ageliferin. A Mn(III)-mediated oxidative radical cyclization reaction was used as the key step to construct core skeleton this pyrrole-imidazole dimer. This approach resembles biogenic [4 + 2] dimerization in intramolecular fashion.

10.1021/ja207386q article EN Journal of the American Chemical Society 2011-09-04

In this work, a typical cylinder-shaped tobacco mosaic virus coat protein (TMVCP) is employed as an anisotropic building block to assemble into triclinic and hexagonal close-packed (HCP) crystals by introducing cysteine residues at the 1 3 sites four histidine C-terminal, respectively. The engineered functional groups of in TMVCP self-assembly conditions determine thermodynamics kinetics process for forming different crystal structures. results show that TMVCPs are thermodynamically driven...

10.1021/acsnano.7b08316 article EN ACS Nano 2018-01-19

Three new copper(<sc>ii</sc>) complexes with single-crystal-to-single-crystal (SCSC) transformation and dissolution–recrystallization structural (DRST) have been synthesized fully characterized.

10.1039/c7ce01919j article EN CrystEngComm 2017-12-15

Two-dimensional (2D) DNA origami is widely used for applications ranging from excitonics to single-molecule biophysics. Conventional, single-layer 2D exhibits flexibility and curvature in solution; however, that may limit its suitability as a structural template. In contrast, wireframe rendered with six-helix bundle edges offers local control over duplex orientations enhanced in-plane rigidity. Here, we investigate the 3D structure of these assemblies using cryo–electron microscopy...

10.1126/sciadv.abn0039 article EN cc-by-nc Science Advances 2022-05-20

In the process of solving inverse kinematics six-degrees-of-freedom collaborative robots, numerical solution has problems such as low accuracy and singular configurations. Moreover, due to high coupling its position attitude, direct closed-form fails. To address these problems, an algorithm that combines solutions was proposed. The Jacobian matrix established based on forward equation robot. Its obtained by a value decomposition using Manocha elimination method avoid singularities matrix....

10.1177/17298806241228372 article EN cc-by International Journal of Advanced Robotic Systems 2024-01-01

In order to diagnose cancer, a sample must be removed, prepared, and examined under microscope, which is expensive, invasive, time consuming. Fiber optic fluorescence endomicroscopy, where an image guide used obtain high-resolution images of tissue in vivo, has shown promise as alternative conventional biopsies. However, the resolution standard endomicroscopy limited by fiber bundle sampling frequency out-of-focus light. A system presented incorporates plastic, achromatic objective increase...

10.1117/1.jbo.18.9.096003 article EN Journal of Biomedical Optics 2013-09-03

This work investigated the effect of sodium (Na) and potassium (K) ions permeation on optical properties vanadium dioxide (VO2) deposited three different glass substrates: silica-soda-lime (SL), silica-potash-soda (PS) fused quartz (FQ), respectively. The VO2 thin films were prepared by reactive magnetron sputtering. Microstructure compositions determined X-ray diffraction (XRD), energy dispersive spectroscopy (EDX) photoelectron (XPS). Morphology was characterized atomic force microscopy...

10.1364/ome.9.000663 article EN cc-by Optical Materials Express 2019-01-18
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