Introduction: Nile tilapia is cichlid fish. Globally second important culture fish after carp. Chemical pollution of aquatic environments increased, seriously harming fisheries and ecosystems alike. Methods: Three glass aquarium 45.72 x 60.96 cm was used. One control others were treatment groups. Different concentration detergent used 0.2 g/l for low dose 0.4 high treatment. Experiment conducted 28 days. Stock density 6 fishes per aquarium. The blood samples preserved in EDTA tubes...

Introduction: Cancer is characterized by the uncontrolled proliferation of abnormal cells, capable invading surrounding tissues. Breast cancer very common in females, about 25%. The Complete Blood Count a standard diagnostic assessment routinely ordered physicians to assess various diseases. Objectives: purpose this work was investigate clinical characteristics with significant role hematological parameters breast patients. Materials and methods: Seventy cases were enrolled, 15 subjects...

The study aimed to assess the literature explore efficacy of different nanoparticles that play a role in suppressing various heavy metals cause breast cancer. Breast cancer is prevalent reason death among females around world. Heavy metals, including arsenic, beryllium, cadmium, nickel, hexavalent chromium, and much more, expansion types cancer, mainly Nanomedicine has unbelievable potential for developing treatment diagnosis by inventive biocompatible nanocomposites treatment. Gold...

Sindh sparrows, prevalent in region of Pakistan, are non-migratory birds abundant human-inhabited areas globally, except Antarctica. Given their close association with human settlements, these serve as crucial indicators for biological monitoring regions affected by pollution. This study focused on assessing the hematological parameters and heavy metal concentrations various organs sparrows Punjab Pakistan. The collected blood samples underwent analysis indices concentrations. results...

Background: Cancer is an unequal growth of cells that have capability to invade and spread in parts organism. It starts from the breast tissues, frequently inner covering milk channels. Objective: The objective study was identify novel somatic alternations oncogenes tumor suppressor genes cancer. Methods: Whole-exome sequencing performed DNA extracted samples people Jinnah hospital Lahore, Pakistan. Results: There were nineteen age group 27 73 tissue specimens collected six patients. Age...

Background: Diabetes mellitus (DM) is a chronic non-communicable endocrine disorder characterized by hyperglycemia. Streptozotocin (STZ) naturally occurring compound which damages pancreatic β cells and has been broadly implemented to produce an animal model of DM. The cytotoxic effect STZ accompanying the synthesis ROS bases oxidative stress injury in cells. Objectives: In present study, induction on apoptotic genes as well glucose metabolism investigated. Methods: two groups albino rats...

Background: Notopterous notopterous belongs to catfishes and are 2nd main group of freshwater fishes. Objectives: To measure morphometric characters heavy metals in fish from River Ravi. Methodology: Morphometric measurements was made by measurement tape weight calculated digital balance. Heavy detection also studied. Results: It found that, 105.85±26.620 g, length with tail 21.03±1.60 cm, without 19.30±1.5 cm. The distance eyes 1.47±0.30 nostrils 0.7±0.09 Mandibles 2.59±0.30 maxilla...

Abstract: Breast cancer is one of the most widespread and lethal malignancies afflicting females globally. The global incidence breast on rise, with an anticipated 4.4 million cases by 2070. Notably, constitutes approximately 25% all diagnoses. In realm biomedical sciences, nanotechnology has ushered in a transformative era, particularly therapy diagnostics. Nanoparticles offer capability to tailor specific sizes, elevated surface-to-volume ratios proving advantageous for drug distribution...

Abstract Background: A cataract is the clouding of lens in eyes, and it a major cause blindness worldwide, especially tropical regions where significant portion population resides developing nations. Purpose: This study, conducted as population-based study at Ali Trust Eye Hospital Okara, aimed to assess relationship between cataracts other risk factors patients. Methods: total 1999 patients were included clinical information such sex, age, education level was collected. In addition, each...

Introduction: Cataract is characterized by the clouding of crystalline lens fibers in eyes. Smoking has been identified as risk factor for several common and serious eye diseases, including age-related macular degeneration, glaucoma, cataracts, all which can lead to irreversible blindness. This study aimed examine relationship between tobacco smoking non-smoking with prevalence cataracts both urban rural populations Pakistan. Methodology: epidemiological was conducted Okara, involving...

Fibromyalgia is a widespread pain disorder characterized by chronic, diffuse pain, about 1 to 5% around world. While more prevalent in women and adults, it can also manifest children adolescents. The specific pathophysiology of fibromyalgia remains unclear, but associated with neuronal over sensitization, reduced conditioned modulation, cognitive dysfunction, memory loss, impaired information processing. It has now been categorized as somatic symptom disorder. This study aimed investigate...

Abstract: Cancer is a major global health concern and hereditary disease brought on by alterations in the genetic code that controls how cells behave. In United States other countries, breast cancer very common among females. Through development of innovative biocompatible Nanocomposites for therapy, which demonstrate highly appropriate manner nanoparticles, Nanomedicine offers incredible potential to develop treatment diagnosis. More than 60% anticancer medications market today are derived...

Cataract is a condition in which lens visualization decreases. In Pulverulent cataract nuclear opaqueness varies among individuals. Blue dot non-hereditary and extends earlier stage. Ralliform an unusual type, like corals, show finger projections. severe cataract, methionine, about 60% or more have been originated membrane form of methionine sulfoxide ionine sulfone. Cortical posterior subcapsular cataracts are strongly associated with the environment, for example, UV exposures, diabetes,...

The primary aim of this study was to assess the morphological characteristics and feeding preferences Sindh sparrow. A total 20 sparrow samples were collected from marshes District Bahawalnagar, Punjab, Pakistan. Measurements including bodyweight, length, tail wingspan, single wing tarsal, metatarsal, head size, bill body circumference recorded. Significant differences found in morphometric between male female sparrows. Specific measurements taken for sparrows, weight (6.11 ± 0.11g), length...

Abstract Cancer is a type which involves irregular progression of cells with the capacity to enter and move other portions body. Breast cancer starts from breast tissues, mostly inner coating milk ducts. It categorized into various methods by, grade, stage receptors status. very common in females worldwide. Whole-exome sequencing (WES) was done DNA removed tumors six patients Jinnah hospital Lahore, Pakistan. There were 19 age 27 73 tissue sample collected 6 patients. The distribution shows...

Background: Cancer is a condition that involves the irregular progression of cells with capacity to enter and move other portions body. Peto’s paradox shows there no relation between large body size cancer risk. Objectives: To assess phylogenetic analysis oncogenes tumor suppressor genes breast cancer. Methods: Data was collected from ensemble genome browser NCBI. A BLAST search done, FASTA sequences were collected. MEGA X version 5 software used for analysis. Alignment made by Clustal W,...

Antimicrobial medications have been crucial in both animals and humans to reduce infections death rate. Antibiotic resistance is found all bacteria including E. coli, P. aeruginosa, Enterobacter spp. Klebsiella To find out the effective medication necessary cure disease resulted from bacteria. The purpose of study was characterize, test antibiotic patterns against novel strains division. This conducted accordance declarations Helsinki. Stool samples were collected. Bacteria isolated...

aims: to explore diseases in pakistani people background: Cataract is a non-communicable eye disease worldwide, with the greatest number of patients middle and low income nations. objective: The study aimed find association socioeconomic status cataract Pakistani population method: A survey based was performed collect questionnaire Performa relevant information from by consent form under declaration Helsinki. result: It observed that 46.05% males 53.95 conclusion: including illiteracy rate,...