A5087822981- Sperm and Testicular Function
- Aldose Reductase and Taurine
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Carbon dioxide utilization in catalysis
- Cholesterol and Lipid Metabolism
- Catalytic C–H Functionalization Methods
- Neonatal Respiratory Health Research
- Cancer-related molecular mechanisms research
- Congenital heart defects research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Reproductive System and Pregnancy
- Renal and related cancers
- Estrogen and related hormone effects
- Single-cell and spatial transcriptomics
- Circular RNAs in diseases
- Reproductive Biology and Fertility
- Asymmetric Hydrogenation and Catalysis
- Retinoids in leukemia and cellular processes
- Ferroptosis and cancer prognosis
- Natural product bioactivities and synthesis
Nantong University
2023-2025
Nantong Maternity and Child Health Hospital
2024
It is very desirable to develop a facile controllable method for selective semihydrogenation of alkynes alkenes with cheap and safe hydrogen donor but remains big challenge. H2O one the best choices transfer hydrogenation agent world, development methods synthesizing E- Z-alkenes using as source worthwhile. In this article, palladium-catalyzed synthesis from was reported. The use di-tert-butylphosphinous chloride (t-Bu2PCl) triethanolamine/sodium acetate (TEOA/NaOAc) essential...
Background Oligospermia is one of the most common reasons for male infertility which troubling numerous couples child-bearing age. This investigation scrutinizes implications and mechanistic underpinnings ursolic acid’s effect on busulfan-induced oligospermia in mouse models. Methods A singular intraperitoneal injection busulfan at a dosage 30 mg/kg induced oligospermia. Two weeks subsequent to this induction, mice were subjected various dosages acid (10, 30, 50 body weight, respectively)...
Objective Hydroxytyrosol (HT), a polyphenolic component identified in olive oil and leaves, represents one of the most extensively investigated natural phenol due to its diverse beneficial biological properties. Recent studies have shown that HT exhibits protective effects on reproductive function can improve sperm quality. However, precise effect underlying mechanism oligozoospermia remain unclear. This study aims investigate across varying concentrations oligozoospermia. Methods...
Ferroptosis, induced by iron overload and an imbalance in redox homeostasis, promotes the generation of reactive oxygen species (ROS), leading to iron-dependent lipid peroxides (LPO) oxidative stress. Lipid peroxidation is essential for progression spermatogenesis. However, its can lead reproductive system damage oligoasthenospermia, a critical cause oligoasthenospermia. Isatin (ISA) naturally occurring compound that widely distributed lobsters, crustaceans, shellfish various plants. It...
Ursolic acid is a natural pentacyclic triterpene found in some medicinal plants and foods, has various good biological functions including protection against reproductive damage. To find more compounds with protection, we synthesized ursonic ursolic as the lead compound. The protective effect of was evaluated mouse model oligozoospermia induced by busulfan. results indicated that increased concentration epididymal sperm, promoted recovery testicular morphology after treatment Testosterone,...