A5078275921- COVID-19 epidemiological studies
- HIV-related health complications and treatments
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- COVID-19 Clinical Research Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Poisoning and overdose treatments
- Veterinary Pharmacology and Anesthesia
- Pesticide Exposure and Toxicity
- Vaccine Coverage and Hesitancy
- Cardiac Imaging and Diagnostics
- Long-Term Effects of COVID-19
- HIV/AIDS drug development and treatment
- Bipolar Disorder and Treatment
- melanin and skin pigmentation
- Antibiotic Use and Resistance
- Nutritional Studies and Diet
- Urinary Tract Infections Management
- Gut microbiota and health
- Lipoproteins and Cardiovascular Health
- COVID-19 Impact on Reproduction
- Body Composition Measurement Techniques
- Systemic Lupus Erythematosus Research
- Diet and metabolism studies
- HIV/AIDS Research and Interventions
Ministry of Health
2020-2025
Mulungushi University
2022-2025
University Teaching Hospital
2017-2025
University of Zambia
2017-2023
Livingstone Hospital
2019-2021
The effect of HIV infection on COVID-19 outcomes is unclear.Studies in South Africa (1) and the United Kingdom (2) found an independent association between mortality; however, other studies have not poor either status among hospitalized patients (3-5) or HIV-associated factors such as CD4 count, viral load, type antiretroviral therapy (ART) (6).The remains urgent question sub-Saharan Africa, where many countries are experiencing dual epidemics, capacity to treat severe limited.Using data...
Introduction: Antimicrobial stewardship (AMS) can improve the rational use of antibiotics in hospitals. This study assessed impact a multifaceted AMS intervention on antibiotic and prescribing patterns at three tertiary hospitals Zambia. Methods: Point Prevalence Surveys (PPS) were conducted August 2022 October 2023. It was part 3-year demonstration project that aimed to optimize treating urinary tract infections (UTIs) bloodstream (BSIs) various health sector settings Up 170 medical records...
Coronavirus disease 2019 (COVID-19) vaccines are highly effective for reducing severe and mortality. However, vaccine effectiveness data limited from Sub-Saharan Africa. We report COVID-19 against progression to in-hospital mortality in Zambia.
Background With the introduction of effective antiretroviral therapy (ART), people living with HIV (PLWH) are surviving longer and at risk for developing metabolic abnormalities that contribute to cardiovascular disease (CVD). In Sub-Saharan Africa (SSA), there is a paucity epidemiological data on lipid profiles among young adults receiving ART. This study aimed estimate prevalence low high-density lipoprotein cholesterol (HDL-c), cardioprotective class, whether it differed by age ART in...
Background Hypertension is common in people living with HIV (PLWH) on antiretroviral therapy (ART). In the general population and experimental animal models, incidence of hypertension greater males than females, especially during premenopausal period. However, it not known whether there are sex differences associated ART, factors contributing to incident among PLWH have been well characterized. this study, we aimed determine time course, initiating ART. Methods results We conducted a...
Pernicious anemia (PA) is a rarely considered cause of in HIV-infected population and seldom on the list differential diagnoses. However, PA can have serious consequences if misdiagnosed or left untreated. We present case 38-year-old HIV-positive man who was diagnosed with PA, which preceded by one-year history vitiligo. Our reminder for clinicians to high index suspicion an autoimmune process as potential individuals.
Amitraz is a widely available insecticide but whose human poisoning highly under-recognized and mistaken for organophosphate poisoning. As result, it often mismanaged possibly resulting in suboptimal clinical outcomes. We present case of 55-year-old man who ingested pesticide 3 hours prior to admission following suicide attempt.His condition rapidly deteriorated necessitating the Intensive Care Unit. there no known effective antidote current medical practice, he was managed supportively with...
Amitraz is a widely available insecticide but whose human poisoning highly under-recognized and mistaken for organophosphate poisoning. As result, it often mismanaged possibly resulting in suboptimal clinical outcomes. We present case of 55-year-old man who ingested pesticide 3 hours prior to admission following suicide attempt.His condition rapidly deteriorated necessitating the Intensive Care Unit. there no known effective antidote current medical practice, he was managed supportively with...
Identifying and treating the cause of pulmonary symptoms in HIV patients with underlying systemic lupus erythematosus (SLE) can be very challenging. Delays diagnosing active SLE lead to significant morbidity even mortality. We report case an HIV-positive woman who presented severe respiratory distress. A 42-year-old a 7-month history anorexia, progressive dyspnoea, productive cough. She had been put on treatment for tuberculosis pneumocystis jiroveci pneumonia several months by referring...
Abstract Objective Dyslipidaemia and obesity have a synergistic effect on the development of cardiovascular diseases (CVDs). Anthropometric measurements often been used as surrogate markers for indices with diverse results. We evaluated best index predicting dyslipidaemia among anthropometric body fat bio-electric impedance analysis (BIA). Results Among 116 adults, 62 (53.4%) were female. The median age was 39 years (quartile (Q)1, Q3: 20.8, 65.4). Waist circumference (odds ratio (OR) 4.54;...
Abstract Background COVID-19 vaccines are highly effective for reducing severe disease and mortality. However, vaccine effectiveness data is limited from sub-Saharan Africa, where SARS-CoV-2 epidemiology has differed other regions. We report against progression to in-hospital mortality in Zambia. Methods conducted a retrospective cohort study among admitted patients at eight treatment centers across Zambia during April 2021 through March 2022. Patient demographic clinical information...
Abstract The novel coronavirus disease of 2019 (COVID-19); caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has presented a unique range clinical manifestations. Thought to be primarily disorder during its early outbreak in China December 2019, it now emerged from various scientific studies that manifestation COVID-19 is indeed protean. This paper aimed at exploring proxies can used increase index suspicion for resource-limited settings like Zambia reviewing four cases our...
The novel coronavirus disease of 2019 (COVID-19); caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has presented a unique range clinical manifestations. Thought to be primarily disorder during its early outbreak in China December 2019, it now emerged from various scientific studies that manifestation COVID-19 is indeed protean. This paper aimed at exploring proxies can used increase index suspicion for resource-limited settings like Zambia, reviewing four cases our health...
The novel coronavirus disease of 2019 (COVID-19); caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has presented a unique range clinical manifestations. Thought to be primarily disorder during its early outbreak in China December 2019, it now emerged from various scientific studies that manifestation COVID-19 is indeed protean. This paper aimed at exploring proxies can used increase index suspicion for resource-limited settings like Zambia, reviewing four cases our health...