A5074301079- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Cardiovascular Issues in Pregnancy
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Blood Coagulation and Thrombosis Mechanisms
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Disease Prevention
- Electrolyte and hormonal disorders
- Reproductive System and Pregnancy
- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Neuropeptides and Animal Physiology
- Reproductive Physiology in Livestock
- Pregnancy-related medical research
- Thermoregulation and physiological responses
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Congenital Heart Disease Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- Pregnancy and Medication Impact
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Vascular anomalies and interventions
KU Leuven
2023
Universitair Ziekenhuis Leuven
2023
Maastricht University Medical Centre
2005-2022
University Medical Center Utrecht
2012-2019
Utrecht University
2012-2019
Maastricht University
1998-2013
University Medical Center
2012-2013
St George Hospital
2012
UNSW Sydney
2012
Radboud University Nijmegen
1980-2011
Objective. To test the hypothesis that in pregnancies complicated by intrauterine growth retardation (IUGR) maternal cardiovascular adaptation is already abnormal first weeks of pregnancy. Setting. University Hospital Maastricht, The Netherlands. Subjects. Fourteen healthy pregnant women, recruited from subfertility clinic. Ten were uneventful and four resulted birth retarded infants. Methods. Maternal status was followed longitudinally combined M‐mode Doppler echocardiography. Studies...
In Brief OBJECTIVE: To determine the prevalence of metabolic syndrome postpartum in women with a history pregnancy complicated by early-onset vascular disorders compared late-onset disorders. METHODS: this retrospective cohort study 849 (preeclampsia; gestational hypertension; hemolysis, elevated liver enzymes, low platelets syndrome; eclampsia; placental abruption; fetal growth restriction; and stillbirth as result insufficiency) were divided into (delivery before 32 weeks gestation, n=376)...
Preeclampsia is associated with a 4-fold higher risk for developing remote chronic hypertension. accompanied by left ventricular hypertrophy and decreased diastolic function, which may or not resolve postpartum. We tested the hypothesis that increased measures of cardiac geometry function persisting ≥ 6 months postpartum in normotensive women history preeclampsia precede development later Formerly preeclamptic (n=652) underwent echocardiography at 9 (range, 6-19) excluded preexisting...
To test the hypothesis that volume adaptation in pregnancies complicated by fetal growth restriction (FGR) is already abnormal very early pregnancy. In six later FGR, homeostasis first 8 weeks was compared to ten normal pregnancies. Creatinine clearance, volume-dependent hormones, hemodilution-related variables, and ultrasonic cardiovascular dimensions were measured weekly between 5 10, second third trimesters, postpartum. Differences two groups analyzed nonparametric tests. Very pregnancy,...
The progressive rise in uterine blood flow during pregnancy is accompanied by outward hypertrophic remodeling of the artery (UA). This process involves changes arterial smooth muscle cells and extracellular matrix. Acute increases stimulate endothelial production nitric oxide (NO). It remains to be established whether NO synthase (eNOS) involved pregnancy-related remodeling. We tested hypothesis that absence eNOS results a reduced capacity UA leading decline neonatal outcome. nonpregnant...
To determine whether the anatomy of an obstetric brachial plexus lesion (OBPL) is causally related to preceding history.Anatomical classification OBPL during reconstructive neurosurgical treatment in consecutive infants who had surgery for between 1986 and 1994 relating these findings with characteristics birth.De Wever Hospital, Heerlen, The Netherlands.All surgical 1 April January (n = 130).An Erb's C5-C6 injury was preceded more frequently by a difficult breech birth (19/26 cases or 73%)....
This study was performed with Dahl salt-sensitive (DS) and salt-resistant (DR) rats to detect differences in cardiovascular hemodynamics renal responses that might be involved initiating salt-induced hypertension DS rats. The effects of 4 weeks 8% NaCl diet were studied conscious, male DR which vascular urinary catheters had been previously implanted. Results compared those obtained from control groups on 1% diet. salt did not develop hypertension, cardiac output blood volume unchanged;...
Aims: To study the relationship between volume and pressure load on one hand relative wall thickness (RWT) other in former preeclamptic women.Methods: In 654 PE women, blood (BP) PV (iodine 125 albumin indicator dilution technique) where measured. was indexed for body surface area (BSA). Echocardiography performed to calculate RWT. The population divided 4 subgroups consisting of women with either normal- or high-systolic BP (sysBP) (<140 versus ≥140mmHg, respectively) low-PV index (>1373...