A5041037533- Antimicrobial Resistance in Staphylococcus
- Diversity and Career in Medicine
- Bacterial Identification and Susceptibility Testing
- Global Health and Surgery
- Sepsis Diagnosis and Treatment
- Clinical Reasoning and Diagnostic Skills
- Nosocomial Infections in ICU
- Emergency and Acute Care Studies
- Bacterial biofilms and quorum sensing
- Health and Medical Research Impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma and Emergency Care Studies
- Streptococcal Infections and Treatments
- Healthcare cost, quality, practices
- Hematological disorders and diagnostics
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Healthcare and Environmental Waste Management
- Bacteriophages and microbial interactions
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Airway Management and Intubation Techniques
- Cell death mechanisms and regulation
- Respiratory Support and Mechanisms
Rutgers New Jersey Medical School
2021-2025
Johnson University
2025
Rutgers, The State University of New Jersey
2021-2025
Rutgers Sexual and Reproductive Health and Rights
2025
University of Abuja Teaching Hospital
2021
Nationwide Children's Hospital
2021
Georgetown University
2019
Johns Hopkins Medicine
2019
Johns Hopkins University
2019
Clinicians commonly obtain endotracheal aspirate cultures (EACs) in the evaluation of suspected ventilator-associated infections. However, bacterial growth EACs does not distinguish colonization from infection and may lead to overtreatment with antibiotics. We describe development impact a clinical decision support algorithm standardize use ventilated PICU patients.We monitored EAC using statistical process control chart. compared rate Poisson regression quasi-experimental interrupted time...
ABSTRACT Biological sex is known to affect the incidence and outcomes of infection, varying significantly by pathogen. The bacterial pathogen Acinetobacter baumannii recognized as a serious global healthcare threat worldwide, yet understanding how biological impacts its infection course limited. We previously documented in murine model acute pneumonia that female mice were more susceptible but there are no published studies looking at humans according sex. conducted retrospective cohort...
OBJECTIVES: Previously, we implemented a comprehensive decision support tool, “New Fever Algorithm,” to the evaluation of PICU patients with new fever or instability. This tool was associated decline in culture rates without safety concerns. We assessed impact algorithm on testing practices by identifying proportion cultures pre- vs. post-implementation that were discordant guidance and may have been avoidable. DESIGN: Retrospective 12 months post-quality improvement intervention. SETTING:...
Staphylococcus lugdunensis is a coagulase-negative staphylococcal bacterium (CoNS) that colonizes the skin. While infectious endocarditis (IE) caused by S. rare, it noteworthy because has been associated with an aggressive clinical course. In this report, we present case of culture-negative IE complicated brain abscesses, vision deficits, and progressive heart failure ultimately required mitral valve replacement. The causative agent was eventually identified as through molecular testing...
Bacterial virulence genes are often regulated at the transcriptional level by multiple factors that respond to different environmental signals. Some act directly on genes; others control pathogenesis adjusting expression of downstream regulators or accumulation signals affect regulator activity. While regulation has been studied extensively during in vitro growth, relatively little is known about how gene adjusted infection. Such information important when a particular product candidate for...
Abstract Background Clinicians obtain endotracheal aspirate (ETA) cultures from mechanically ventilated patients in the pediatric intensive care unit (PICU) for evaluation of ventilator-associated infection (i.e., tracheitis or pneumonia). Positive prompt clinicians to treat with antibiotics even though ETA cannot distinguish bacterial colonization infection. We undertook a quality improvement initiative standardize use infections among hospitalized children. Methods A multidisciplinary team...
Bacterial virulence genes are often regulated at the transcriptional level by multiple factors that respond to different environmental signals. Some act directly on genes; others control pathogenesis adjusting expression of downstream regulators or accumulation signals affect regulator activity. While regulation has been studied extensively during in vitro growth, relatively little is known about how gene adjusted infection. Such information important when a particular product candidate for...