A5027446290- Tryptophan and brain disorders
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Circadian rhythm and melatonin
- Metabolism, Diabetes, and Cancer
- Cancer, Stress, Anesthesia, and Immune Response
- Viral Infections and Vectors
- Extracellular vesicles in disease
- Neuropeptides and Animal Physiology
- Pain Management and Opioid Use
- Mosquito-borne diseases and control
- Diet, Metabolism, and Disease
- Pain Mechanisms and Treatments
- Diet and metabolism studies
UNSW Sydney
2023-2024
Neuroscience Research Australia
2022-2024
The University of Sydney
2018
Garvan Institute of Medical Research
2018
Disruption of circadian rhythms occurs in rotating shift-work, jetlag, and individuals with irregular sleep schedules. Circadian disruption is known to alter inflammatory responses impair immune function. However, there limited understanding how modulates cancer-induced inflammation. Inflammation a hallmark cancer linked worse prognosis impaired brain function patients. Here, we investigated the effect on inflammation an orthotopic breast model. Using validated chronic jetlag protocol that...
Stress and inflammation are risk factors for schizophrenia. Chronic psychosocial stress is associated with subcortical hyperdopaminergia, a core feature of Hyperdopaminergia arises from midbrain neurons, leading us to hypothesise that changes in response pathways may occur this region. To identify whether transcriptional glucocorticoid mineralocorticoid receptors (NR3C1/GR, NR3C2/MR) or other signalling molecules (FKBP4, FKBP5) exist schizophrenia midbrain, we measured gene expression the...
Dopamine dysregulation contributes to psychosis and cognitive deficits in schizophrenia that can be modelled rodents by inducing maternal immune activation (MIA). The selective estrogen receptor (ER) modulator, raloxifene, improve cognition men women with schizophrenia. However, few studies have examined how raloxifene may exert its therapeutic effects mammalian brain both sexes during young adulthood (age relevant most prevalent age at diagnosis). Here, we tested the extent which alters...