Chi-Chang Ho

ORCID: 0000-0002-5069-2194
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About
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Research Areas
  • Air Quality and Health Impacts
  • Air Quality Monitoring and Forecasting
  • Climate Change and Health Impacts
  • Vehicle emissions and performance
  • Liver Disease Diagnosis and Treatment
  • Odor and Emission Control Technologies
  • Advanced Chemical Sensor Technologies
  • Noise Effects and Management
  • Atmospheric chemistry and aerosols
  • Urban Transport and Accessibility
  • Hepatitis B Virus Studies
  • Water Quality and Pollution Assessment
  • Water Quality Monitoring and Analysis
  • Heavy metals in environment
  • Genetic factors in colorectal cancer
  • Public Health Policies and Education
  • Cancer Immunotherapy and Biomarkers
  • Geophysical Methods and Applications
  • Toxic Organic Pollutants Impact
  • Food Security and Health in Diverse Populations
  • Dental Radiography and Imaging
  • Health disparities and outcomes
  • Hepatitis C virus research
  • COVID-19 impact on air quality
  • Ferroptosis and cancer prognosis

National Taiwan University
2010-2024

Taichung Veterans General Hospital
2024

Institute of Statistical Science, Academia Sinica
2020-2023

China Medical University
2021

National University of Singapore
2011

Abstract Background Although a number of studies have reported on the health effects fine particulate matter (PM2.5) exposure, particularly in North American and European countries as well China, evidence about intermediate to high levels PM2.5 exposures is still limited. We aimed investigate associations between long-term exposure risk cardiopulmonary disease incidence Taiwan with exposure. Methods A cohort Taiwanese adults, who participated 2001, 2005, 2009 2013 National Health Interview...

10.1093/ije/dyac082 article EN International Journal of Epidemiology 2022-04-14

Air pollution is a risk factor for hepatocellular carcinoma (HCC). However, the effect of air on HCC in patients with hepatitis remains unclear.

10.1097/jcma.0000000000001053 article EN cc-by-nc-nd Journal of the Chinese Medical Association 2024-01-11

Abstract Microsatellite-instable (MSI), a predictive biomarker for immune checkpoint blockade (ICB) response, is caused by mismatch repair deficiency (MMRd) that occurs through genetic or epigenetic silencing of MMR genes. Here, we report mechanism MMRd and demonstrate protein phosphatase 2A (PP2A) deletion inactivation converts cold microsatellite-stable (MSS) into MSI tumours two orthogonal pathways: (i) increasing retinoblastoma phosphorylation leads to E2F DNMT3A/3B expression with...

10.1038/s41467-021-27620-x article EN cc-by Nature Communications 2021-12-15

SUMMARY The recent outbreak of H1N1 has provided the scientific community with a sad but timely opportunity to understand influence socioeconomic determinants on pandemic mortality. To this end, we have used data collected from 341 US counties model deaths/1000 using 12 predictors discover why certain reported fewer deaths compared other counties. These were then build decision tree. tree developed was predict mortality for whole USA. Our estimate 7667 are in accord lower bound CDC 8870...

10.1017/s0950268811001464 article EN Epidemiology and Infection 2011-08-11

Biochemical response is an important prognostic indicator in chronic hepatitis B (CHB) patients receiving nucleotide/nucleoside analogues (NAs). However, the effects of air pollution alanine aminotransferase (ALT) normalization remain elusive. This longitudinal study recruited 80 e antigen–negative CHB who received NAs. ALT levels were measured during first year anti-hepatitis virus therapy. Normal defined as <19 U/L for females and <30 males, risk factors associated with abnormalities...

10.1097/md.0000000000034276 article EN cc-by-nc Medicine 2023-10-27

Our study aimed to compare bone scintigraphy and dual-layer detector spectral CT (DLCT) with multiphase contrast enhancement for the diagnosis of osteoblastic lesions in patients prostate cancer. The cancer detected on DLCT were divided into positive group (pBS) negative (nBS) based scintigraphy. A total 106 (57 nBS 49 pBS) was included. parameters each lesion measured from including Hounsfield unit (HU), 40-140 keV monochromatic HU, effective nuclear numbers (Zeff), Iodine no water (InW)...

10.1038/s41598-024-55427-5 article EN cc-by Scientific Reports 2024-03-04

Abstract. Most odor nuisance investigations rely on either human olfactory examination or on-site sampling and analytical techniques, but these methods are often subject to spatial temporal limitations thus impractical for locating emission sources. This study developed an alternative approach with a dual-optical sensing system, meteorological station, the combination of factor cluster analyses identify characterize sources multiple air contaminants. Factor were employed establish profile...

10.5194/amt-12-5347-2019 article EN cc-by Atmospheric measurement techniques 2019-10-08

O-31A6-6 Background/Aims: The emission of PCDD/F (Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans) is a serious issue in many countries. Previous references indicated that human activities are major sources PCDD/F, including from waste incineration, power generation, energy industries, other high-temperature sources. Several studies England the United States reported incinerator was one important contributors to ambient concentration. In Taiwan, municipal incinerators...

10.1097/01.ede.0000391932.94350.15 article EN Epidemiology 2010-12-14

Abstract. Most odor nuisance investigations rely on either human olfactory examination or on-site sampling and analytical techniques, but these methods are often subject to spatial temporal limitations thus impractical for locating emission sources. This study developed an alternative approach with a dual-optical sensing system, meteorological station, the combination of factor cluster analyses identify characterize sources multiple air contaminants. Factor were employed establish profile...

10.5194/amt-2018-344 preprint EN cc-by 2019-02-14

Abstract This technical report aimed to determine the sources of water pollution in a major river northern Taiwan by using characteristics actual industrial wastewater and effective variance chemical mass balance (EV-CMB) model. River samples from 9 sampling sites 14 profiles potential were collected total 52 metal elements analyzed. To monitor levels pollutants samples, index (MI) is used. The model results identified may suggest existence unknown sources. study demonstrates feasibility...

10.21203/rs.3.rs-1383438/v1 preprint EN cc-by Research Square (Research Square) 2022-03-07
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