- Spinal Fractures and Fixation Techniques
- Bone fractures and treatments
- Spine and Intervertebral Disc Pathology
- Sarcoma Diagnosis and Treatment
- Scoliosis diagnosis and treatment
- Orthopaedic implants and arthroplasty
- Gastrointestinal disorders and treatments
- Mesenchymal stem cell research
- Bone Tissue Engineering Materials
- Management of metastatic bone disease
- Gastrointestinal Tumor Research and Treatment
- Renal cell carcinoma treatment
- Tissue Engineering and Regenerative Medicine
- Diverticular Disease and Complications
- Cancer Diagnosis and Treatment
- Anatomy and Medical Technology
- Elbow and Forearm Trauma Treatment
- Vascular anomalies and interventions
- Bariatric Surgery and Outcomes
- Foreign Body Medical Cases
- Cutaneous Melanoma Detection and Management
- Intraperitoneal and Appendiceal Malignancies
- Orthopedic Surgery and Rehabilitation
- Medical Imaging and Pathology Studies
- Neuroendocrine Tumor Research Advances
University of Southern California
2023-2025
Case Western Reserve University
2024
University School
2024
Broward Health
2024
Keck Hospital of USC
2022-2024
Aventura Hospital and Medical Center
2022-2023
HCA Healthcare
2023
<h3>Background</h3> As the elderly population grows, increasing prevalence of osteoporosis presents a unique challenge for surgeons. Decreased bone strength and quality are associated with hardware failure impaired healing, which may increase rate revision surgery development complications. The purpose this review is to determine impact on postoperative outcomes patients cervical degenerative disease or deformity. <h3>Methods</h3> A systematic using Preferred Reporting Items Systematic...
Ex vivo regional gene therapy is a promising tissue-engineering strategy for bone regeneration: osteogenic mesenchymal stem cells (MSCs) can be genetically modified to express an osteoinductive stimulus (e.g., morphogenetic protein-2), seeded onto osteoconductive scaffold, and then implanted into defect exert therapeutic effect. Compared recombinant human BMP-2 (rhBMP-2), which approved clinical use, may have unique benefits related the addition of MSCs sustained release BMP-2. However,...
OBJECTIVES: To describe subperiosteal elevation of the ulnar nerve and compare to anterior transposition in situ decompression techniques. METHODS: Design: Retrospective comparative study. Setting: Urban Level 1 trauma center. Patient Selection Criteria: Distal humerus fractures (Orthopaedic Trauma Association/AO 13) treated with open reduction internal fixation between 2014 2022. Outcome Measures Comparisons: Rate preoperative postoperative neuritis grouped by management nerve. During...
When delivering cells on a scaffold to treat bone defect, the cell seeding technique determines number and distribution of within scaffold, however optimal has not been established. This study investigated if human adipose-derived stem (ASCs) transduced with lentiviral vector overexpress morphogenetic protein 2 (BMP-2) loaded using dynamic orbital shaker could reduce total dose required heal critical sized defect when compared static seeding. Human ASCs were onto collagen/biphasic ceramic...
Background: There is considerable heterogeneity in findings and a lack of consensus regarding the interplay between osteoporosis outcomes patients with lumbar degenerative spine disease. Therefore, purpose this systematic review meta-analysis was to gather analyze existing data on effect radiographic, surgical, clinical following surgery for spinal disease.Methods: A performed determine incidence adverse after surgical intervention diseases. The approach focused radiographic outcomes,...
Study Design: Systematic review and meta-analysis. Objective: To compare radiographic outcomes across lumbar interbody fusion (LIF) techniques, assessing segmental global lordosis restoration. Summary of Background Data: LIF is a commonly utilized procedure to treat various spinal conditions, including degenerative pathology adult deformity. Common approaches include posterior (PLIF), transforaminal (TLIF), anterior (ALIF), oblique (OLIF), lateral (LLIF). Methods: A systematic meta-analysis...
This study describes the complication profile of modern cryoablation utilizing probes as an adjuvant during open surgical treatment orthopedic tumors.A retrospective, single-surgeon was performed for patients receiving cryoprobe cryoablation. Demographic information, malignancy-related and operative details, clinical courses were collected. Outcomes assessed included rates complications, recurrence, correlations between number or cycles performed.In this 148-patient study, 67.6% had...
Tracheo and broncho esophageal fistulas their potential complications in adults are seldom encountered clinical practice but carries a significant morbidity mortality.We present case of 39-year-old otherwise healthy man who presented to our hospital after ingestion drain cleaner substance during suicidal attempt. He unexpectedly suffered from cardiac arrest his stay the intensive care unit. The patient had developed extensive segmental trachea-broncho-esophageal fistulous tracks that led...
Novel treatment strategies for segmental bone loss in orthopaedic surgery remain under investigation. Regional gene therapy that involves transduction of mesenchymal stem cells with a lentiviral vector expresses BMP-2 has gained particular interest as this strategy provides osteogenic and osteoinductive factors growth. In particular, transduced adipose-derived stems (ASCs) marrow-derived (BMSCs) have emerged the leading candidates defects preclinical models. The aim present study was to...
Introduction: Small bowel neuroendocrine tumors (SBNETs) arise from the enterochromaffin cells that line gastrointestinal tract and secrete serotonin. Although considered rare, SBNETs have been increasing in incidence prevalence, likely due to increase imaging studies. We present a case of an elderly man who presented with small obstruction was found multicentric SBNET mid-ileum. Case Description/Methods: An 85-year-old emergency department complaints diffuse abdominal pain, nausea, vomiting...
Introduction: GI melanomas are extremely rare and require thorough investigation. Most metastatic from an oculocutaneous lesion, however, if not found, termed melanoma of unknown primary (MUP.) MUP represents only 2% all yet it is a major cause mortality. Common areas metastasis involve the lymph nodes, small intestines, subcutaneous sites. We present case that developed large abdominal masses within 7 months. Case Description/Methods: A 68 year old male presented with 1 week LLQ pain...
Introduction: Diverticular disease is one of the most common issues encountered by gastroenterologists. It estimated that around half those above age 60 will have colonic diverticula and up to 25% these individuals experience a complication such as diverticulitis. In small intestine, majority are found in duodenum (79%). Diverticula jejunum ileum rather rare, affecting only 0.5%-2.3% patients. with jejunoileal diverticula, their clinical course largely asymptomatic but 10% time patients can...
Introduction: Prostate cancer is the leading cause of malignancy and 2nd overall cancer-related deaths for men in US today. Diagnosis involves transrectal ultrasound-guided prostate biopsy (TRUS-guided biopsy), which has remained gold standard. It provides a rapid diagnosis with relatively low complication profile. Post biopsy, patients may commonly experience mild rectal bleeding, prostatitis, hematospermia or hematuria. However, one rarest complications TRUS-guided massive bleeding...