A5102710017- Plant Pathogenic Bacteria Studies
- Genomics and Phylogenetic Studies
- Enzyme Structure and Function
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cytokine Signaling Pathways and Interactions
- Polyamine Metabolism and Applications
- Plant-Microbe Interactions and Immunity
- Enzyme Production and Characterization
- Film in Education and Therapy
- Bee Products Chemical Analysis
- Congenital heart defects research
- Proteins in Food Systems
- Biopolymer Synthesis and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Macrophage Migration Inhibitory Factor
- Education, Safety, and Science Studies
- Attention Deficit Hyperactivity Disorder
- Adolescent and Pediatric Healthcare
- Meat and Animal Product Quality
- Meningioma and schwannoma management
- Adrenal Hormones and Disorders
- Genetics, Aging, and Longevity in Model Organisms
- Microbial metabolism and enzyme function
- RNA modifications and cancer
Inje University Sanggye Paik Hospital
2019
University of Ulsan
2013-2015
Ulsan College
2013-2015
Sangmyung University
2008-2009
// Hyesoon Kim 1 , Seung-Hwan Lee Mi-Ni 2 Goo Taeg Oh Kyung-Chul Choi 1,3 and Eun Young Department of Biomedical Sciences, University Ulsan College Medicine, Seoul, Republic Korea, Division Life Ewha Womans University, 3 Pharmacology, Korea Correspondence: Choi, email: Keywords : p53, inflammation, endothelial cell, Del-1 Received August 23, 2013 Accepted October 1, Published 3, Abstract Developmental locus-1 (Del-1) is an endothelium-derived anti-inflammatory molecule that downregulated by...
DcHSP17.7, a small heat shock protein from carrot ( Daucus carota L.), was expressed in Escherichia coli to examine its functional mechanism under stress. When transformed cells expressing DcHSP17.7 were exposed 50 °C for 1 h, the number of viable ≈4-fold higher than that control. amount soluble proteins compared, it more twofold control, suggesting may function as molecular chaperone preventing heat-inducible degradation. Native-PAGE followed by immunoblot analysis showed E. , present an...
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that regulates leukocyte recruitment, thereby playing pivotal role in the regulation of innate and adaptive immunity tumor progression. Elevated levels MIF are associated with numerous inflammatory disorders cancers. To determine whether developmental endothelial locus-1 (Del-1) regulated MIF, RAW264.7 macrophages were treated Del-1 assessed using ELISA. The results showed was downregulated by Del-1, an endogenous...
Xanthomonas oryzae pv. (Xoo) causes bacterial blight (BB), which is one of the most devastating diseases rice in rice-growing countries. D-Alanine-D-alanine ligase A (DdlA), coded by Xoo0352 gene, was expressed, purified and crystallized. DdlA an enzyme that involved D-alanine metabolism biosynthesis essential peptidoglycan precursor, it catalyzes formation D-alanyl-D-alanine from two D-alanines, thus attractive antibacterial drug target against Xoo. The crystals diffracted to 2.3 resolution...
Xanthomonas oryzae pv. (Xoo) causes bacterial blight of rice (Oryza sativa L.), one the most devastating diseases in rice-growing countries. XometC, a cystathionine γ-lyase (CGL) like protein that is an antibacterial drug-target against Xoo, was cloned, expressed, purified and crystallized. CGL catalyzes second step reverse-transsulfuration pathway, which essential for metabolic interconversion sulfur-containing amino acids cysteine methionine. Crystals two different shapes, plate-shaped...
Xanthomonas oryzae pv. (Xoo) causes bacterial blight in rice, which is one of the most devastating diseases rice-cultivating countries. The Xoo0880 (fabD) gene coding for a malonyl-CoA–acyl carrier protein transacylase (MCAT) from Xoo was cloned and expressed Escherichia coli. MCAT an essential enzyme that catalyzes key reaction fatty-acid synthesis bacteria plants: conversion malonyl-CoA to malonyl-acyl protein. FabD purified crystallized order elucidate its three-dimensional structure...
The disease bacterial blight results in serious production losses of rice Asian countries. aroB gene encoding dehydroquinate synthase (DHQS), which is a potential antibiotic target, was identified from the plant-pathogenic bacterium Xanthomonas oryzae pv. (Xoo). DHQS plays an essential role synthesis aromatic compounds shikimate pathway. (Xoo1243) cloned Xoo and corresponding protein subsequently overexpressed Escherichia coli. purified crystallized using hanging-drop vapour-diffusion method...
Peptide deformylase (PDF) catalyzes the removal of N-formyl group from N-terminus newly synthesized polypeptides; this process is crucial for cell survival. As it an antibacterial drug target against Xanthomonas oryzae pv. (Xoo), PDF Xoo was cloned, expressed, purified and crystallized. Native crystals diffracted to 2.7 Å resolution belonged hexagonal space P6122, with unit-cell parameters a = b 59.0, c 266.3 Å. One monomer present in asymmetric unit, corresponding crystal volume per protein...
The gltX gene from Xanthomonas oryzae pv. (Xoo1504) encodes glutamyl-tRNA synthetase (GluRS), one of the most important enzymes involved in bacterial blight (BB), which causes huge production losses rice worldwide. GluRS is a class I-type aminoacyl-tRNA (aaRS) that primarily responsible for glutamylation tRNAGlu. It plays an essential role protein synthesis, as well regulation cells, all organisms. As it represents target development new antibacterial drugs against BB, determination...
This study investigated quality of life in Korean juvenile inmates with attention-deficit/hyperactivity disorder (ADHD) and the impact behavioral emotional problems on life.
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Abstract Del-1 is an endogenous endothelial-derived inhibitor of LFA-1-mediated leukocyte adhesion (Choi et al. Science 2008). As has high expression in brain, we assessed here its role neuroinflammation experimental autoimmune encephalomyelitis (EAE), the rodent model multiple sclerosis. We found decreased inflamed spinal cord mice subjected to EAE protocol. Moreover, Del-1-deficiency resulted increased severity, associated with inflammatory cell recruitment cord. Immunohistochemistry...
Xanthomonas oryzae pv. (Xoo) causes bacterial blight, which is one of the most devastating diseases rice (Oryza sativa L.) in many rice-growing countries. The coding sequence Xoo2316 (a predicted 6-phosphogluconolactonase; 6PGL) from Xoo was cloned and expressed Escherichia coli. 6PGL an enzyme that involved second step pentose phosphate pathway, essential for synthesis nucleotide sugars NADPH, main source reducing power. protein purified crystallized order to elucidate molecular basis its...
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This study was to examine the mediation effect of organizational culture institution in relationship between principal's professionalism and teacher’s play efficacy teacher-child interaction. The subjects were 200 teachers working at kindergartens daycare centers located South Korea. Questionnaire carried out. For data analysis, using SPSS, reliability frequency descriptive statistical correlation multiple regression analysis. Finally, order significance mediating organization bootstrap...