Jianxin Liu

ORCID: 0000-0002-5077-4990
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Research Areas
  • Immune cells in cancer
  • IL-33, ST2, and ILC Pathways
  • Drug Transport and Resistance Mechanisms
  • Nanoparticle-Based Drug Delivery
  • Renal Diseases and Glomerulopathies
  • Natural Compound Pharmacology Studies
  • Bioactive Compounds and Antitumor Agents
  • Berberine and alkaloids research
  • Immune responses and vaccinations

Hunan University of Traditional Chinese Medicine
2022-2024

Hunan University
2024

Purpose: Sinomenine hydrochloride (SH) is used to treat chronic inflammatory diseases such as rheumatoid arthritis and may also be efficacious against Immunoglobulin A nephropathy (IgAN).However, no trial has investigated the molecular mechanism of SH on IgAN.Therefore, this study aims investigate effect IgAN.Methods: The pathological changes IgA C3 depositions in kidney an IgAN rat model were detected by periodic acid-Schiff (PAS) direct immunofluorescence staining.After extracting T B...

10.2147/dddt.s449119 article EN cc-by-nc Drug Design Development and Therapy 2024-04-01

<title>Abstract</title> Background Nifuroxazide (NFX) is a broad-spectrum antibacterial agent widely used to treat infectious diarrhea since 1966. In recent years, the discovery of inhibitory effect NFX on signal transducer and activator transcription 3 has prompted extensive research it as potential anticancer drug. However, there are very few studies its anti-inflammatory effects. Purpose We want investigate mechanism related anti-inflammation both <italic>in vitro</italic> vivo</italic>....

10.21203/rs.3.rs-5272522/v1 preprint EN cc-by Research Square (Research Square) 2024-11-20

Gambogic acid (GA), a kind of polyprenylated xanthone derived from Garcinia hanburyi tree, has showed spectrum anticancer effects both in vitro and vivo with low toxicity. However, up to now, there is little information about the GA on esophageal cancer. In this study, we aim test cancer EC9706 cells. We established nanoscale imaging method based AFM evaluate reactive oxygen species- (ROS-) mediated regarding morphological ultrastructural changes The obtained results demonstrated that could...

10.1155/2022/1422185 article EN Scanning 2022-07-22
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