Jijun Yu

ORCID: 0000-0002-5103-6711
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About
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Research Areas
  • Metabolomics and Mass Spectrometry Studies
  • Single-cell and spatial transcriptomics
  • CRISPR and Genetic Engineering
  • Advanced biosensing and bioanalysis techniques
  • Bioinformatics and Genomic Networks
  • Gene expression and cancer classification

High-throughput genetic screening based on CRISPR/Cas9 or RNA-interference (RNAi) enables the exploration of genes associated with phenotype interest a large scale. The rapid accumulation public available data provides wealth knowledge about genotype-to-phenotype relationships and valuable resource for systematic analysis gene functions. Here we present CRISP-view, comprehensive database RNAi datasets that span multiple phenotypes, including in vitro vivo cell proliferation viability,...

10.1093/nar/gkaa809 article EN cc-by Nucleic Acids Research 2020-09-30

Extensive amounts of multi-omics data and multiple cancer subtyping methods have been developed rapidly, generate discrepant clustering results, which poses challenges for molecular subtype research. Thus, the development identification consensus subtypes is essential. The lack intuitive easy-to-use analytical tools has posed a barrier. Here, we report on COnsensus Molecular SUbtype Cancer (COMSUC) web server. With COMSUC, users can explore more than 30 cancers based eight methods, five...

10.1371/journal.pcbi.1008769 article EN cc-by PLoS Computational Biology 2021-03-18
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