A5042871049- Plant and animal studies
- Lepidoptera: Biology and Taxonomy
- Mosquito-borne diseases and control
- Genetic diversity and population structure
- Viral Infections and Vectors
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Genomics and Phylogenetic Studies
- Zoonotic diseases and public health
- Insect symbiosis and bacterial influences
- Ecology and Vegetation Dynamics Studies
- Genetic and phenotypic traits in livestock
- COVID-19 epidemiological studies
- Morphological variations and asymmetry
- Animal Diversity and Health Studies
- Animal Disease Management and Epidemiology
- Neurobiology and Insect Physiology Research
- Genetics, Bioinformatics, and Biomedical Research
- Parasitic Diseases Research and Treatment
- Influenza Virus Research Studies
- Evolution and Genetic Dynamics
- Plant Virus Research Studies
- Malaria Research and Control
- Vector-borne infectious diseases
- Plant and Fungal Species Descriptions
California Academy of Sciences
2013-2024
Pacific Biosciences (United States)
2006-2021
University of Hawaiʻi at Mānoa
2006-2021
University of Hawaii System
2006-2021
Golden Gate University
2013-2014
University of Puerto Rico System
2002-2006
University of Puerto Rico at Río Piedras
2001-2006
The University of Texas at Austin
2006
The University of Melbourne
2004
Universidad de Los Andes
2004
The evolutionary importance of hybridization and introgression has long been debated. Hybrids are usually rare unfit, but even infrequent can aid adaptation by transferring beneficial traits between species. Here we use genomic tools to investigate in Heliconius, a rapidly radiating genus neotropical butterflies widely used studies ecology, behaviour, mimicry speciation. We sequenced the genome Heliconius melpomene compared it with other taxa chromosomal evolution Lepidoptera gene flow among...
Sexual isolation is a critical form of reproductive in the early stages animal speciation, yet little known about genetic basis divergent mate preferences and preference cues young species. Heliconius butterflies, well for their diversity wing color patterns, assortatively as result divergence male patterns. Here we show that specific cue used by cydno pachinus males to recognize conspecific females patches on wings. In addition, segregates with forewing hybrids, indicating association...
In metropolitan areas people travel frequently and extensively but often in highly structured commuting patterns. We investigate the role of this type human movement epidemiology vector-borne pathogens such as dengue. Analysis is based on a metapopulation model where mobile humans connect static mosquito subpopulations. find that, due to frequency dependent biting, infection incidence populations almost independent duration contact. If population not uniformly distributed between patches...
Butterfly Apartheid Heliconius butterflies show differences in mimetic color patterns across geographic races associated with of assortative mating, suggesting that ecological speciation may be ongoing. Chamberlain et al. (p. 847 ) demonstrate mating on the basis pattern mimicry generates reproductive isolation between cydno species and subspecies within polymorphic populations Ecuador. Furthermore, it appears these traits are controlled by a single gene affects pigment wing formation...
The rate at which genomes diverge during speciation is unknown, as are the physical dynamics of process. Here, we compare full genome sequences 32 butterflies, representing five species from a hybridizing Heliconius butterfly community, to examine genome-wide patterns introgression and infer how divergence evolves Our analyses reveal that initial restricted small fraction genome, largely clustered around known wing-patterning genes. Over time, rapidly, due primarily origin new divergent...
Abstract Vector‐borne diseases are a major health burden, yet factors affecting their spread only partially understood. For example, microbial symbionts can impact mosquito reproduction, survival, and vectorial capacity, hence affect disease transmission. Nonetheless, current knowledge of mosquito‐associated communities is limited. To characterize the bacterial eukaryotic multiple vector species collected from different habitat types in endemic areas, we employed next‐generation 454...
Recent years have seen the greatest ecological disturbances of our times, with global human expansion, species and habitat loss, climate change, emergence new previously-known infectious diseases. Biodiversity loss affects disease risk by disrupting normal relationships between hosts pathogens. Mosquito-borne pathogens respond to changing dynamics on multiple transmission levels appear increase in disturbed systems, yet current knowledge mosquito diversity relative abundance vectors as a...
Dengue is an emerging tropical disease infecting tens of millions people annually. A febrile illness with potentially severe hemorrhagic manifestations, dengue caused by mosquito-borne viruses (DENV-1 to -4) that are maintained in endemic transmission large urban centers the tropics periodic epidemic cycles at 3- 5-year intervals. Puerto Rico (PR), a major population center Caribbean, has experienced increasingly epidemics since multiple serotypes were introduced beginning late 1970s. We...
Strain IK-1(T) was isolated from decaying tissues of the shrub Wikstroemia oahuensis collected on O'ahu, Hawai'i. Cells were rods that stained Gram-negative. Gliding motility not observed. The strain oxidase-negative and catalase-positive. Zeaxanthin major carotenoid. Flexirubin-type pigments detected. most abundant fatty acids in whole cells grown R2A iso-C(15:0) one or both C(16:1)ω7c C(16:1)ω6c. Based comparisons nucleotide sequence 16S rRNA gene, closest neighbouring type strains...
We compare the historical demographies of two Müllerian comimetic butterfly species: Heliconius erato and melpomene . These species show an extensive parallel geographic divergence in their aposematic wing phenotypes. Recent studies suggest that this coincident mosaic results from simultaneous demographic processes shaped by extrinsic forces over Pleistocene climate fluctuations. However, DNA sequence variation at rapidly evolving unlinked nuclear loci, Mannose phosphate isomerase ( Mpi )...
Abstract High-throughput nucleic acid sequencing has greatly accelerated the discovery of viruses in environment. Mosquitoes, because their public health importance, are among those organisms whose viromes being intensively characterized. Despite deluge sequence information, our understanding major drivers influencing ecology mosquito remains limited. Using methods to increase relative proportion microbial RNA coupled with RNA-seq we characterize and other symbionts three species collected...
Arthropod-borne viruses significantly impact human health. They span multiple families, all of which include not known to cause disease. Characterizing these representatives could provide insights into the origins their disease-causing counterparts. Field-caught Aedes aegypti mosquitoes from Nakhon Nayok, Thailand, underwent metagenomic shotgun sequencing reveal a Bunyavirus closely related Phasi Charoen (PhaV) virus, isolated in 2009 Ae. near Bangkok. Phylogenetic analysis this virus...
Recent studies indicate that relatively few genomic regions are repeatedly involved in the evolution of Heliconius butterfly wing patterns. Although this work demonstrates a number cases where homologous loci underlie both convergent and divergent pattern change among different species, it is still unclear exactly how many variation across genus. To address question for erato, we created fifteen independent crosses utilizing four most distinct color races analyzed segregation total 1271 F2...
We report a dense genetic linkage map of Heliconius erato, neotropical butterfly that has undergone remarkable adaptive radiation in warningly colored mimetic wing patterns. Our study exploited natural variation segregating cross between H. erato etylus and himera to localize color pattern loci on containing amplified fragment length polymorphisms (AFLP), microsatellites, single-copy nuclear loci. unambiguously identified all 20 autosomal groups the sex chromosome (Z). The spanned total 1430...
With over 20 parapatric races differing in their warningly colored wing patterns, the butterfly Heliconius erato provides a fascinating example of an adaptive radiation. Together with matching its co-mimic melpomene, H. also represents textbook case Müllerian mimicry, phenomenon where common warning signals are shared amongst noxious organisms. It is great interest to identify specific genes that control mimetic patterns and melpomene. To this end we have undertaken comparative mapping...
Summary Vector‐borne diseases persist in transmission systems that usually comprise heterogeneously distributed vectors and hosts leading to a highly heterogeneous case distribution. In this study, we build on principles of classical mathematical epidemiology investigate spatial heterogeneity disease risk for vector‐borne diseases. Land cover delineates habitat suitability vectors, land use determines the distribution humans. We focus exposure dengue Hawaiian island Oahu, where vector Aedes...
Abstract It is unknown whether homologous loci underlie the independent and parallel wing pattern radiations of Heliconius butterflies. By comparing locations color patterning genes on linkage maps we show that three act similarly in two are similar positions chromosomes.
Research over the last 10 years highlights increasing importance of hybridization between species as a major force structuring evolution genomes and potentially providing raw material for adaptation by natural and/or sexual selection. Fueled research in few model systems where phenotypic hybrids are easily identified, into introgression (the flow genes species) has exploded with advent whole-genome sequencing emerging methods to detect signature at or chromosome level. Amongst these general...
As a geographically isolated island chain with no native mosquitoes, Hawaii is model for examining the mechanisms behind insect vector invasions and their subsequent interactions each other human populations. The yellow fever mosquito, Aedes aegypti, Asian tiger Ae. albopictus, have been responsible epidemics of dengue in Hawaii. one world's earliest locations to be invaded by both species, Hawaii's history particularly relevant because species are currently invading new areas worldwide...