We studied the prevalence of different types dementia in an elderly population Stockholm, Sweden, relation to age, sex, and education. The study confirmed Alzheimer9s disease (AD) as most frequent type positive association dementias with even advanced ages. In contrast previously reported data, we found same proportion AD vascular age strata, no sex differences regarding types. Finally, less educated people had a higher all dementias, due essentially alcoholic unspecified dementia. was...

Few studies have examined the associated factors of antepartum depressive and anxiety symptoms (ADS AAS) in low-income countries, yet World Health Organization identifies disorders as second leading cause global disease burden by 2020. There is a paucity research on mental their predictors among pregnant women Bangladesh. This study aims to estimate prevalence explore cross-section rural Bangladeshi women.The used cross-sectional data originating from community-based prospective cohort 720...

Abstract Monoamine oxidase A (MAOA) harbours a polymorphic upstream variable-number tandem repeat (u-VNTR). The MAOA-L allele of the u-VNTR leads to decreased gene expression levels in vitro and has been found increase risk conduct disorder males with childhood adversities. Early-life adversities have associated hypermethylation glucocorticoid receptor (NR3C1). In this study, we first performed genetic association analysis MAOA using individuals depression (n = 392) controls 1276). Next, DNA...

Most of the available evidence on effects depression is based in- and out-patient samples focusing individuals suffering from major depression. The aims this study were to examine cognitive functioning in population-based determine whether performance varies as a function subgroup.Population-based (aged 20-64 years) with (N = 68), dysthymia 28), mixed anxiety-depressive disorder 25) minor 66) examined variety tasks (i.e. episodic memory, verbal fluency, perceptual-motor speed mental...

<b><i>Objective:</i></b> To examine preclinical depressive symptoms 3 years before the diagnosis of AD. <b><i>Methods:</i></b> The authors compared incident AD patients and nondemented individuals in terms baseline mood- motivation-related depression, assessed whether are related to self-perceived memory problems. Participants came from a population-based longitudinal study on aging dementia Stockholm, Sweden. sample consisted 222 persons older than 74 who were followed for 3-year interval....

There is a high prevalence of antepartum depression and low birth weight (LBW) in Bangladesh. In high- low-income countries, prior evidence linking maternal depressive anxiety symptoms with infant LBW conflicting. no research on the association between mental disorders This study aims to investigate independent effect among women rural district A population-based sample 720 pregnant from two subdistricts was assessed for depression, using Edinburgh Postpartum Depression Scale (EPDS),...

Translating scientific evidence into daily practice is complex. Clinical guidelines can improve health care delivery, but there are a number of challenges in guideline adoption and implementation. Factors influencing the effective implementation remain poorly understood. Understanding barriers facilitators important for development strategies. The aim this study was to determine perceived clinical compliance depression psychiatric care. This qualitative conducted at two clinics Stockholm,...

Background Depression is common and tends to be recurrent. Alternative treatments are needed that non-stigmatising, accessible can prescribed by general medical practitioners. Aims To compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive–behavioural therapy (ICBT) treatment as usual (TAU). A secondary aim was assess changes in self-rated work capacity. Method total 946 patients diagnosed with mild moderate depression were recruited...

Abnormalities in the circadian clockwork often characterize patients with major depressive and bipolar disorders. Circadian clock genes are targets of interest these patients. CRY2 is a gene that participates regulation evening oscillator. This mood disorders where lack switch from to morning oscillators has been postulated.We observed marked diurnal variation human mRNA levels peripheral blood mononuclear cells significant up-regulation (P = 0.020) following one-night total sleep...

Background The Alcohol Use Disorders Identification Test ( AUDIT ) and ‐Consumption ‐C) are commonly used in population surveys but there few validations studies the general population. Validity should be estimated samples close to targeted setting. This study aims validate ‐C a sample PART Stockholm, Sweden. Methods We subsample age 20 64 that answered postal questionnaire including who later participated psychiatric interview n = 1,093). Interviews using Schedules for Clinical Assessment...

Background Exercise can relieve both depressive and anxiety disorders it is therefore of importance to establish movement patterns mildly moderately affected sufferers estimate the treatment potential. The aim describe physical activity people by mild moderate and/or symptoms using objective measures activity. Methods design study was cross-sectional data from 165 aged 18–65 years, with disorder (scoring ≥10 on PHQ-9). Diagnoses were made Mini International Neuropsychiatric Interview (MINI)...

Abstract Early life exposure to infection, anti-infectives and altered immune activity have been associated with elevated risk of some psychiatric disorders. However, the from in fetal has proposed be confounded by familial factors. The hypothesis this study is that antibiotic drug during period first two postnatal years for later development disorders children. All births Finland between 1996 2012, 1 million births, were studied exposure: mothers pregnancy children years. followed up a wide...

Objective : To study the relationship between subjective memory complaints, cognitive functioning, and clinical diagnosis of dementia. Design Cross‐sectional, total‐population survey. Measurements A two‐phase was done. All 2368 were screened by Mini‐Mental State Examination (MMSE). Then 314 who positive a sample 354 negative examined clinically (by examining subject interviewing an informant) for DMS‐III‐R criteria dementia, Clinical Dementia Rating (CDR) scale severity dementia presence...

Community-based samples of old adults with current major depression (n = 17; mean age 83.29 years) and healthy 51; were examined on a variety episodic recall recognition tasks. Results indicate depression-related deficits in that reduced, but not eliminated, recognition. Control Ss able to utilize cognitive support the form more study time item organizability free recall, whereas depressed not. However, both groups showed equal gains from provision category cues beneficial effects prior...

The circadian clock is driven by transcription-translation feedback loops and regulates rhythms that approximate the 24-hr day-night cycle or light-dark transitions. Disruptions of are common in depressed patients, expressed for example as sleep disturbances. Genetic variations core genes may part explain these abnormalities. To investigate whether genetic variation associates with vulnerability to depression, we genotyped 18 a Swedish population based sample. indicative association winter...

Whether or not cannabis use may increase the risk for depression and/or anxiety is clear. For one thing, it has been possible to draw a definitive conclusion regarding direction of causality, i.e. whether increases depression/anxiety vice versa. This study aimed at examining associations between use, and anxiety, using all three measures as both exposure outcome.Data were obtained from longitudinal cohort comprising 8598 Swedish men women, aged 20-64, with three-year-follow-up.Adjusted sex...