- Digital Mental Health Interventions
- Mental Health Research Topics
- Sleep and related disorders
- Impact of Technology on Adolescents
- Mental Health Treatment and Access
- Behavioral Health and Interventions
- Dermatology and Skin Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Substance Abuse Treatment and Outcomes
- Sleep and Wakefulness Research
- Asthma and respiratory diseases
- Circadian rhythm and melatonin
- Eating Disorders and Behaviors
- Child and Adolescent Psychosocial and Emotional Development
- COVID-19 and Mental Health
- Schizophrenia research and treatment
- Allergic Rhinitis and Sensitization
- Diabetes Management and Research
- Youth Substance Use and School Attendance
- Parkinson's Disease Mechanisms and Treatments
- Resilience and Mental Health
- Aging and Gerontology Research
- Personality Disorders and Psychopathology
- Telemedicine and Telehealth Implementation
- Problem Solving Skills Development
Karolinska Institutet
2015-2024
Stockholm Health Care Services
2017-2024
Stockholm County Council
2017-2024
Institute of Mental Health
2024
Linköping University
2019
St Vincent's Hospital Sydney
2018
Karolinska University Hospital
2015
To compare treatment effects when patients with insomnia and depression receive for either or depression. A 9-w randomized controlled trial 6- 12-mo follow-up. Internet Psychiatry Clinic, Stockholm, Sweden. Forty-three adults in whom comorbid were diagnosed, recruited via media assessed by psychiatrists. Guided Internet-delivered cognitive behavior therapy (ICBT) Primary outcome measures symptom self-rating scales (Insomnia Severity Index [ISI] the Montgomery Åsberg Depression Rating Scale...
Background Depression is common and tends to be recurrent. Alternative treatments are needed that non-stigmatising, accessible can prescribed by general medical practitioners. Aims To compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive–behavioural therapy (ICBT) treatment as usual (TAU). A secondary aim was assess changes in self-rated work capacity. Method total 946 patients diagnosed with mild moderate depression were recruited...
To evaluate if internet-delivered Cognitive Behavioral Therapy for insomnia (ICBT-i) with brief therapist support outperforms an active control treatment.Adults diagnosed were recruited via media (n = 148) and randomized to either eight weeks of ICBT-i or internet-based treatment. Primary outcome was the severity index (ISI) assessed before after treatment, follow-ups 6 12 months. Secondary outcomes use sleep medication, parameters (sleep diary), perceived stress, a screening negative...
Internet-based cognitive-behavioral therapy (ICBT) has received increased attention as an innovative approach to improve access evidence-based psychological treatments. Although the efficacy of ICBT for social anxiety disorder been established in several studies, there is limited knowledge its effectiveness and application clinical psychiatric care. The purpose this study was evaluate treatment determine significance patient adherence clinic's years experience delivering ICBT.A longitudinal...
This study aimed to demonstrate proof of concept for an adaptive treatment strategy in Internet-delivered cognitive-behavioral therapy (ICBT), where risk failure is assessed early and at-risk patients adapted prevent failure.A semiautomated algorithm 251 undergoing ICBT insomnia with therapist guidance. At-risk were randomly assigned continue standard or receive ICBT. The primary outcome was self-rated symptoms using the Insomnia Severity Index a linear mixed-effects model. main secondary...
Background: Internet-administered self-report measures of social anxiety, depressive symptoms, and sleep difficulties are widely used in clinical trials routine care, but data loss is a common problem that could render skewed estimates symptom levels treatment effects. One way reducing the negative impact missing be to use telephone administration as means complete from online collection. Objective: The aim study was compare convergence Internet difficulties. Methods: Liebowitz Social...
To develop a very brief scale with selected items from the Insomnia Severity Index (ISI), and to investigate psychometric properties of proposed in psychiatric sample. Patient data seven Cognitive Behavioral Therapy (CBT) for insomnia trials regular care were used analyses (N = 280-15 653). The samples included patients screening 6936) or receiving treatment 1725) other conditions. Six criteria relating component structure, sensitivity change clinical representativeness select items....
Insomnia is a common and chronic disorder, cognitive behavioral therapy (CBT) the recommended treatment. Very long-term follow-ups of CBT are very rare, this study aimed to investigate if improvements were stable one ten years after for insomnia (CBT-i). Based on three-armed randomized controlled trial bibliotherapeutic CBT-i, participants received an insomnia-specific self-help book therapist guidance, no or waitlist receiving unguided treatment delay. Six weeks was given 133 diagnosed with...
Resources are spent worldwide on the development of digital platforms and their user interfaces (UIs) for mental health services (DMHS). However, studies investigating potential benefits different UIs DMHS currently lacking. To fill this knowledge gap, aim study was to investigate differences in treatment engagement between two DMHS.A total 397 participants from Swedish general public were randomized (1:1) use a self-guided problem-solving intervention during one week, either with an...
To test the efficacy of a therapist-guided high-intensity internet intervention compared with an unguided low-intensity among individuals alcohol use disorder.A three-group randomized controlled trial follow-up assessments post-treatment (12 weeks) and 6 months post-randomization (primary end-point).General population sample in Sweden.A total 166 on-line self-referred adults (49% males) score 14 (females)/16 (males) or more on Alcohol Use Disorders Identification Test, preceding week...
Background: Parkinson's disease (PD) is often associated with psychological distress and lowered daily functioning.The availability of interventions tailored for people Parkinson very limited.Objective: To study if guided individually-tailored internet-based cognitive behavioral therapy (ICBT) provide additional value to standard medical treatment PD.Methods: Seventy-seven individuals PD self-reported problems general function measured the Work Social Adjustment Scale (WSAS > 15) were...
Depression can negatively impact work capacity, but treatment effects on sick leave and employment are unclear. This study evaluates if internet-based cognitive behavioural therapy (ICBT) or physical exercise (PE), with already reported positive clinical outcome short-term ability, has better employment, long-term ability compared as usual (TAU) for depressed primary care patients (German trials: DRKS00008745).
Parkinson's disease (PD) is often associated with depression and anxiety. The availability of evidence-based psychological interventions low. This pilot study investigates the feasibility preliminary effect internet-based cognitive behavioral therapy (ICBT) for anxiety in PD. 9 patients PD comorbid symptoms on relevant subscale Hospital Anxiety Depression Scale (HADS), either (HADS-D > 7) or (HADS-A received 12 weeks ICBT, specially adapted Primary outcome was change symptoms, measured HADS...
Abstract Telomere attrition is a hallmark of cellular aging and shorter telomeres have been reported in mood anxiety disorders. shortening counteracted by the enzyme telomerase protection also provided antioxidant glutathione peroxidase (GPx). Here, telomerase, GPx, were investigated 46 social disorder (SAD) patients within-subject design with repeated measures before after cognitive behavioral therapy. Treatment outcome was assessed Liebowitz Social Anxiety Scale (self-report), administered...
Background Both internet-based cognitive–behavioural therapy (ICBT) and physical exercise are alternatives to treatment as usual (TAU) in managing mild moderate depression primary care. Aims To determine the cost-effectiveness of ICBT compared with TAU Method Economic evaluation a randomised controlled trial ( N = 945) Sweden. Costs were estimated by service use questionnaire used together effects on quality-adjusted life-years (QALYs). The 3-month healthcare provider perspective care was...
A large proportion of individuals with alcohol problems do not seek psychological treatment, but access to such treatment could potentially be increased by delivering it over the Internet. Cognitive behavior therapy (CBT) is widely recognized as one treatments for which evidence most robust. This study evaluated a new, therapist-guided internet-based CBT program (entitled ePlus) use disorders.Participants in (n = 13) were recruited through an self-help web site ( www.alkoholhjalpen.se ) and,...
Research shows that internet-based cognitive behavioural therapy (iCBT) is an effective treatment for depression. However, little known about how the length of text material in iCBT affects outcomes.The aim this study was to test whether a condensed version depression would be non-inferior existing full-text reducing depressive symptoms at post-treatment. We also wanted non-inferiority secondary outcomes and explore reading speed ADHD as potential moderators.A single-blind randomized...
To minimize the burden in detecting and monitoring Panic Disorder Agoraphobia by developing a very brief scale with selected items from Severity Scale-Self Report (PDSS-SR), to investigate proposed scale's psychometric properties comorbid sample.A sample of 5103 patients Internet Psychiatry Clinic Sweden, diagnosed treated Internet-based cognitive behavioral therapy for panic disorder (n = 1390), social anxiety 1313) or depression 2400), responded PDSS-SR. Six criteria related factor...
Background There is often a waiting period for people who seek psychiatric treatment depression or anxiety. As this delay risks worsening symptoms, an alternative could be to provide intervention that requires minimal resources during the period. Aims The aim was investigate if digital problem-solving delivered in self-guided format with automated features feasible patients on list routine care. Method A total of 12 symptoms anxiety care were given access and monitored over 4 weeks. Primary...
Abstract Background Emerging adulthood is often associated with mental health problems. About one in three university students report symptoms of depression and anxiety that can negatively affect their developmental trajectory concerning work, intimate relationships, health. This interfere academic performance, as mood disorders are key predictors dropout from higher education. A treatment gap exists, where a considerable proportion do not seek help for symptoms. Offering internet...
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by dry skin, eczematous lesions, and an often severe pruritus. The may have negative effect on quality of life also associated with symptoms anxiety depression. Few individuals AD receive any form behavioral intervention. Behavioral interventions for are potentially efficacious but need to be constructed so that they safe, credible, user-friendly. We previously reported feasibility study demonstrated self-management...