- Dermatologic Treatments and Research
- Wound Healing and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Cardiovascular Disease and Adiposity
- Facial Rejuvenation and Surgery Techniques
- Electrospun Nanofibers in Biomedical Applications
- Surgical Simulation and Training
- Neuroendocrine Tumor Research Advances
- Mesenchymal stem cell research
- Dietary Effects on Health
- Facial Trauma and Fracture Management
- Lung Cancer Research Studies
- Polymer Surface Interaction Studies
- Botulinum Toxin and Related Neurological Disorders
- Augmented Reality Applications
- Gastrointestinal Tumor Research and Treatment
- Reproductive Biology and Fertility
- Hair Growth and Disorders
- Enhanced Recovery After Surgery
- Fibroblast Growth Factor Research
- Adipose Tissue and Metabolism
- Neonatal Respiratory Health Research
- Body Contouring and Surgery
- Cellular transport and secretion
- Skin and Cellular Biology Research
Shanghai Ninth People's Hospital
2022-2025
Hubei University of Arts and Science
2025
Shanghai Jiao Tong University
2020-2025
Xiangyang Central Hospital
2025
Shanghai Normal University
2021
Inventions of materials to achieve biocompatibility, bioadhesion, and easy manufacturing are the urgent demand for promoting wound healing in clinical treatment. Hyaluronic acid (HA) is probably ideal candidate current dressing due its well-known biocompatibility. However, unavoidable problem HA dressings their inherent low adhesiveness wounds, which severely impairs treatment efficacy, especially during body movement. Here, we report a one-pot facile fabrication hybrid double-network...
Background Vascular localization is crucial for perforator flap transfer. Augmented reality offers a novel method to seamlessly combine real information with virtual objects created by computed tomographic angiography help the surgeon “see through” skin and precisely localize perforator. The head-mounted display augmented system HoloLens (Microsoft) could facilitate reality–based more convenient safe procedure. Objective aim of this study was evaluate precision HoloLens-based vascular...
Background: The stromal vascular fraction (SVF) of adipose tissue has now been widely used in plastic surgeries, clinical trials and therapies. However, the cell composition SVF undergoes dynamic changes during aging obesity, which may influence efficacy SVF. This study analyzed effects age, harvest site body mass index on Methods: A was performed 162 patients. age ranged from 13 to 88 years old, with (BMI) <25kg/m 2 or ≥ 25kg/m . Fat harvested abdominal region, hips, thighs arms,...
BACKGROUND Gastric neuroendocrine carcinomas (NECs) exhibit aggressive features, such as rapid growth, higher rate of metastasis, and a generally unfavorable prognosis compared to gastric adenocarcinoma. As result, therapeutic options for NECs remain limited, contributing the poor patients. Immunotherapy has emerged promising treatment strategy demonstrated potential partially improve survival patients with NECs. Nevertheless, unique clinical response termed pseudoprogression (PsP) garnered...
UVR-related skin damage is common in daily life. Excessive sunlight exposure, particularly response to ultraviolet B (UVB) radiation, can have adverse effects on the and even induce photosensitive diseases malignancies. UVB exposure leads production of reactive oxygen species (ROS) skin, resulting cell inflammation. Furthermore, it directly inhibits synthesis collagen fibroblasts, contributing degradation subsequently causing aging, wrinkles, erythema. To address this issue, our study...
Restylane Defyne (HARD , with lidocaine) has been shown to be effective and safe for facial augmentation including nasolabial folds (NLFs) in Caucasians. Incorporating lidocaine injectable fillers become a common practice that improves the patient's experience.To evaluate efficacy safety of HARD compared (HAR gold standard HA filler) correction NLFs Chinese population.In this 12-month, randomized, split-face, evaluator-blinded study treatment or HAR adults (n = 173) moderate severe wrinkle...
Extracellular vesicle (EV) mediated intercellular communication determines various physiological and pathological processes that show great potential as therapeutic reagents. While EV trafficking through extracellular matrix (ECM) is influenced by both deformation medium re-organization or viscoelasticity, how mechanics regulates transportation remains unclear. In this work, we introduced a photo-tunable hydrogel platform ECM mimicry allows well-defined viscoelasticity changes of the to...
Heterogeneous dermal fibroblasts are the main components that constitute dermis. Distinct fibroblast subgroups show specific characteristics and functional plasticity determine structure during skin development wound healing. Although researchers have described roles of subsets, this is not completely understood. We review recent evidence supporting understanding about heterogeneity fibroblasts. summarize origins identified profiles subpopulations. The subpopulations in both healthy diseased...
Skin expansion is a useful method for harvesting extra tissue. However, the outcome hardly predictable. A total of 158 patients with 277 expanded skin cases were reviewed and evaluated via photographs. The review evaluation conducted to determine skin’s regenerative condition. overall texture skin, which was deemed good, fair, or poor, evaluated. occurrence five indications limitation regeneration (thinning, color change, stretch marks, varicose vessels, lesions) during recorded. correlation...
Soft-tissue fillers, specifically hyaluronic acid can reduce many signs of aging by treating the associated loss subcutaneous fat and midfacial contour deficiencies. The objective this study was to investigate whether effectiveness safety Belotero Volume Lidocaine (BVL) compared with Restylane (RES, control) is noninferior in treatment severe nasolabial folds (NLFs) Chinese patients.This a prospective, randomized, controlled, split-face clinical study. Overall, 220 patients both sexes...
<sec> <title>BACKGROUND</title> Vascular localization is crucial for perforator flap transfer. Augmented reality offers a novel method to seamlessly combine real information with virtual objects created by computed tomographic angiography help the surgeon “see through” skin and precisely localize perforator. The head-mounted display augmented system HoloLens (Microsoft) could facilitate reality–based more convenient safe procedure. </sec> <title>OBJECTIVE</title> aim of this study was...
Abstract Background : Long-term preservation of adipose tissue is crucial for clinical applications. Researchers should consider both efficiency and biosafety when choosing a cryoprotective agent (CPA) preservation. Glycerol has been applied as nontoxic CPA multiple tissues but not tissue. We aimed to evaluate the efficacy glycerol cryopreservation. Methods Fresh human were obtained from ten patients who underwent liposuction divided into 1 ml samples. Each sample was randomly mixed with...