- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear Physics and Applications
- Advanced X-ray Imaging Techniques
- Electron and X-Ray Spectroscopy Techniques
- Advanced X-ray and CT Imaging
- Cultural Heritage Materials Analysis
- X-ray Diffraction in Crystallography
- Radioactivity and Radon Measurements
- Analytical chemistry methods development
- Ion-surface interactions and analysis
- Trace Elements in Health
- Radiation Shielding Materials Analysis
- Particle Detector Development and Performance
- Bone health and osteoporosis research
- Radiation Detection and Scintillator Technologies
- Mass Spectrometry Techniques and Applications
- Orthopaedic implants and arthroplasty
- Heavy metals in environment
- Advancements in Photolithography Techniques
- Drug Transport and Resistance Mechanisms
- Air Quality and Health Impacts
- Medical Imaging Techniques and Applications
- Atmospheric chemistry and aerosols
- Geochemistry and Geologic Mapping
- Bone health and treatments
TU Wien
2015-2024
Austrian Biolmaging - Verein zur innovativen, korrelativen, multimodalen Bildgebung in Österreich
2020-2021
Austrian Economics Center
2018-2020
University of Vienna
2001-2018
Universities Austria
1995-2016
FH Campus Wien
2015
University of Girona
2010
Geociencias Barcelona
2010
Steklov Mathematical Institute
2010
General Electric (Austria)
2008-2009
Helium atoms ionized by intense few-cycle light pulses in the barrier suppression regime emit spatially coherent extreme ultraviolet continuum extending to photon energies greater than ${E}_{\mathrm{ph}}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}0.5\mathrm{keV}$ ( $\ensuremath{\lambda}<2.5\mathrm{nm}$). The high-energy end of range ${E}_{\mathrm{ph}}\ensuremath{\ge}0.2\mathrm{keV}$ $\ensuremath{\lambda}\ensuremath{\le}6\mathrm{nm}$) was characterized spectrally over a considerable...
Trace elements are chemical in minute quantities, which known to accumulate the bone. Cortical and trabecular bones consist of bone structural units (BSUs) such as osteons packets different mineral content separated by cement lines. Previous studies investigating trace lacked resolution therefore very little is about local concentration zinc (Zn), strontium (Sr) lead (Pb) BSUs human We used synchrotron radiation induced micro X-ray fluorescence analysis (SR μ-XRF) combination with...
Strontium ranelate (SrR) is a relatively new treatment for osteoporosis. In this study we investigated its potential impact on human bone material quality in transiliac biopsies from postmenopausal osteoporotic women treated 3 years with calcium and vitamin D plus either 2 g SrR per day or placebo. Bone mineralization density distribution (BMDD), strontium (Sr) concentration, collagen cross-link ratio, indentation modulus were analyzed by quantitative backscattered electron imaging,...
Selenium content of soils is an important issue due to the narrow range between nutritious requirement and toxic effects upon Se exposure. However, its determination challenging low concentrations within complex matrices that hamper analysis in most spectroscopic techniques. In this study, we explored possibilities several analytical approaches combined with total reflection X-ray (TXRF) spectrometry for soil determinations. The direct a solid suspension using 20 mg fine ground material (<50...
In the present contribution, a critical evaluation of use EDXRF (Energy dispersive X-ray fluorescence spectrometry) for elemental composition determination (K, Ca, Mn, Fe, Cu, Zn, Sr and Rb) coffee samples is presented. Firstly, several sample treatment procedures (pressed pellets loose powder) quantification strategies (fundamental parameters empirical calibration) were evaluated. addition to quality nutritional purposes, information content in can be also useful traceability provenance...
Abstract In humans the toxic trace element lead (Pb) mainly accumulates in skeletal tissue where it resides for a long period. Although Pb is known to play role bone and cartilage diseases, distribution of these tissues mostly unknown. Therefore synchrotron‐radiation‐induced micro x‐ray fluorescence analysis (SR µ‐XRF) various geometries was used determine distributions Pb, Ca, Zn Sr at cartilage‐bone interface human femoral heads patellae. SR µ‐XRF results were matched with backscattered...
This comprehensive review covers the latest published activities using XRF techniques. X-ray analytical equipment continues to be integrated with emission/diffraction/absorption techniques growing use of synchrotron radiation (SR) sources reflected in literature. integration trend was also prevalent development small-scale laboratory equipment. detectors have advanced pixellated systems, micro-calorimeter types and now established silicon drift being readily used by many authors. Matrix...
An existing micro-x-ray fluorescence (micro-XRF) spectrometer designed for light element analysis (6 ≤ Z 14) has been extended to confocal geometry: a second polycapillary x-ray optic introduced in front of the energy dispersive detector. New piezo positioners optimum alignment both optics have installed inside vacuum chamber. The offers now possibility true 3D elemental micrometer regime. Depth resolution varies between 100 μm at 1 keV (Na-Kα) and 30 17.5 (Mo). To further extend analytical...
This review comments on the ever expanding range of work using XRF group techniques published approximately between April 2012 and March 2013. It presents innovative as opposed to wealth contributions that combine spectrometry in conjunction with other analytical those descriptions valuable routine applications during period. New specialised laboratory instruments, X-ray sources data processing procedures have been introduced well further detector development. Portable hand-held systems...
This review offers the reader a wealth of information published between April 2010 and March 2011 concerning analytical endeavours using range conventional hyphenated XRF techniques that encourage user to ensure potential for high spectral sensitivity and, where appropriate, spatial resolution is achieved. The development advanced micro-beam set ups new X-ray optics driven by third generation synchrotron based provide nano-imaging detection nano-particles on single cells whilst TXRF coupled...
Abstract Gadolinium-based contrast agents (GBCAs) are frequently used in patients undergoing magnetic resonance imaging. In GBCAs gadolinium (Gd) is present a bound chelated form. Gadolinium rare-earth element, which normally not human body. Though the blood elimination half-life of about 90 minutes, recent studies demonstrated that some tissues retain gadolinium, might further pose health threat due to toxic effects free gadolinium. It known bone tissue can serve as depot, but so far only...
The use of synchrotron radiation (SR) as an excitation source for total reflection X-ray fluorescence analysis (TXRF) offers several advantages over tube excitation. Detection limits in the fg range can be achieved with efficient low Z well high elements due to features and particular brilliance a wide spectral linear polarization orbital plane. SR-TXRF is especially interesting samples where only small sample masses are available. Lowest detection typically using multilayer monochromators...
This review demonstrates advances in XRF instrumentation, techniques and data processing algorithms published during the last year. Pixellated detectors EDXRF imaging/mapping using a variety of materials readout technologies have set trend that will undoubtedly continue due to improved sensor array fabrication devices are now more widely available. Instrumental development took place at synchrotron beamlines with reports described measurement methodologies for use combinations μ-analytical...
The continuous downscaling of the process size for semiconductor devices pushes junction depths and consequentially implantation to top few nanometers Si substrate. This motivates need sensitive methods capable analyzing dopant distribution, total dose possible impurities. X-ray techniques utilizing external reflection X-rays are very surface sensitive, hence providing a non-destructive tool analysis control. reflectometry (XRR) is an established technique characterization single-...
Grazing incidence XRF (GIXRF) is a very surface sensitive, nondestructive analytical tool making use of the phenomenon total external reflection X-rays on smooth polished surfaces. In recent years method experienced revival, being powerful for process analysis and control in fabrication semiconductor based devices. Due to downscaling size devices, junction depths as well layer thicknesses are reduced few nanometers, i.e. length scale where GIXRF highly sensitive. measures X-ray fluorescence...
Matrix-assisted laser desorption/ionisation mass spectrometric imaging (MALDI MSI) is a technique that provides localized information on intact molecules in sample. Micro X-ray fluorescence (μXRF) allows the examination of spatial distribution elements sample without any morphological changes. These methods have already been applied separately to different tissues, organs, plants and bacterial films, but, best our knowledge, they yet be coupled multimodal analysis. In this proof-of-principle...