Cotyledon orbiculata, commonly known as pig’s ear, is an important medicinal plant of South Africa. It used in traditional medicine to treat many ailments, including skin eruptions, abscesses, inflammation, boils and acne. Many plants have been synthesize metallic nanoparticles, particularly silver nanoparticles (AgNPs). However, the synthesis AgNPs from C. orbiculata has never reported before. The aim this study was using evaluate their antimicrobial immunomodulatory properties. were...

Silver nanoparticles (AgNPs) are the most commercialized nanomaterials and presumed to be biocompatible based on biological effects of bulk material. However, their physico-chemical properties differ significantly materials associated with unique properties. The study investigated antimicrobial cytotoxicity AgNPs synthesized using gum arabic (GA), sodium borohydride (NaBH

Cyclopia intermedia is indigenous to South Africa and used prepare honeybush herbal tea. This aromatic tea has been associated with numerous health benefits, mostly based on anecdotal evidence very few studies reporting the antimicrobial activities. The inhibitory effect growth of important nosocomial microorganisms possible association antioxidant capacity/content various solvent extracts green/unfermented fermented plant material were determined in current study. agar disk diffusion assay...

Nanoparticles (NPs) synthesized using various chemical and physical methods are often cytotoxic which restricts their use in biomedical applications. In contrast, metallic biogenic NPs biological systems such as plant extracts said to be safer production more cost effective. from plants with known medicinal properties can potentially have similar bioactivities these plants. It has been shown that Salvia africana-lutea (SAL) Sutherlandia frutescens (SF) antibacterial activities. This study...

Disposal of agricultural waste has a negative impact on the environment and human health may contribute to greenhouse effect. The field nanotechnology could provide alternative solutions upcycle wastes in safer manner into high-end value products. Organic from plants contain biomaterials that serve as reducing capping agents synthesis nanomaterials with enhanced activities for use biomedical environmental applications. Persea americana (avocado) is fruit high nutritional value; however,...

Background. Hypoxis hemerocallidea is a native plant that grows in the Southern African regions and well known for its beneficial medicinal effects treatment of diabetes, cancer, high blood pressure. Aim. This study evaluated on oxidative stress biomarkers, hepatic injury, other selected biomarkers liver kidneys healthy nondiabetic streptozotocin- (STZ-) induced diabetic male Wistar rats. Materials Methods. Rats were injected intraperitoneally with 50 mg/kg STZ to induce diabetes. The...

The synthesis of silver nanoparticles using biogenic methods, particularly plants, has led to the discovery several effective nanoparticles. In many instances, plant-derived have been shown more activity than plant extract which was used synthesize Silver successfully synthesized medicinal plant, Cotyledon orbiculata. This is a shrub found in Western Cape province South Africa. It long history use traditional medicine treatment wounds and skin infections. C. orbiculata (Cotyledon-AgNPs) were...

Synthesis of gold nanoparticles (AuNPs) using phytochemicals has become tremendously prominent in biomedical applications because its enhanced bioactivity and biocompatibility. In this study, water extracts from the leaves Cyclopia genistoides (C. genistoides), commonly known as honeybush (HB), were used to synthesize (HB-AuNPs). The HB (HBE) served both reducing capping agents synthesis HB-AuNPs. HB-AuNPs characterized by UV–Vis spectrophotometry, dynamic light scattering (DLS),...

Along with the increasing requirement for efficient organic conversions using green chemistry, there is a need to develop highly and eco-friendly catalytic reaction systems. Gold nanoparticles (AuNPs)-based nanocatalysts are promising candidates reduction of environmental pollutants, such as nitroaromatics dyes. This study reports on synthesis AuNPs Carpobrotus edulis (C. edulis) fruit aqueous extract (CeFE) their activities. The CeFE induced rapid gold (III) salt form monodispersed...

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty disease, is a associated with metabolic syndrome (MetS), especially obesity, hypertension, diabetes, hyperlipidemia, and hypertriglyceridemia. MASLD in 43–44% of patients can progress to steatohepatitis (MASH), 7–30% these cases will scarring (cirrhosis). To date, the mechanism its progression not completely understood there were no therapeutic strategies specifically tailored for...

Nanotechnology has recently received much interest in various fields, including medicine. South Africa (SA) was the first country to adopt technology with aim of enhancing national bio-economy and global competitiveness by using innovative nanotechnology-based solutions. Since its inception 2005 SA, researchers have seized opportunities increase develop niche areas for application health, energy, food, agriculture, water sectors. We ventured into this field performed pioneering work on...

Diabetes mellitus (DM) is becoming one of the leading causes death worldwide because its adverse complications that include cardiovascular related diseases and chronic kidney disease. DM considered a menace to public health due unavailability adequate drugs manage this condition, especially in poor developing countries such as those African continent. Proper management treatment lacking, which possibly explains escalating percentages morbidity mortality associated with it. In Africa, result...

Gold nanoparticles (AuNPs) were synthesized using three red wine extracts (RW-Es); by varying temperature, pH, concentrations of RW-Es and gold salt. The RW-AuNPs characterized UV–vis, transmission electron microscopy (TEM), dynamic light scattering (DLS), the Fourier Transform Infra-red Spectroscopy (FT–IR). Their stability was evaluated in water, foetal bovine serum (FBS), phosphate-buffered saline (PBS), Dulbecco's Modified Eagle Medium (DMEM) UV–Vis. effect on KMST-6 cell viability MTT...

<sec> <title>BACKGROUND</title> Although 61% of married women in Bangladesh use contraceptive methods, the prevalence is lower rural areas than urban areas. This has implications for rates Sexually Transmissible Infections (STIs). Cases STIs are under-reported and consequently, awareness level, knowledge of, services to minimize prevent STI transmission among low. Mobile health (mHealth) present an emerging platform increasing at risk. </sec> <title>OBJECTIVE</title> To explore medical...